IRIS
Inga, Alberto
 Distribuzione geografica
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Continente #
NA - Nord America 8.263
EU - Europa 1.120
AS - Asia 861
SA - Sud America 17
OC - Oceania 8
Continente sconosciuto - Info sul continente non disponibili 6
AF - Africa 5
Totale 10.280
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Nazione #
US - Stati Uniti d'America 8.256
SG - Singapore 403
IT - Italia 247
CN - Cina 236
SE - Svezia 219
UA - Ucraina 180
FI - Finlandia 145
GB - Regno Unito 139
VN - Vietnam 92
DE - Germania 74
BG - Bulgaria 42
ID - Indonesia 41
JO - Giordania 33
RU - Federazione Russa 18
TR - Turchia 16
CZ - Repubblica Ceca 14
BR - Brasile 8
IN - India 8
HK - Hong Kong 7
AT - Austria 6
CA - Canada 6
FR - Francia 6
JP - Giappone 6
CL - Cile 5
IE - Irlanda 5
NL - Olanda 5
A2 - ???statistics.table.value.countryCode.A2??? 4
AU - Australia 4
ES - Italia 4
LK - Sri Lanka 4
NZ - Nuova Zelanda 4
BE - Belgio 3
DZ - Algeria 3
KR - Corea 3
AR - Argentina 2
CH - Svizzera 2
DK - Danimarca 2
EU - Europa 2
GR - Grecia 2
KZ - Kazakistan 2
LU - Lussemburgo 2
NO - Norvegia 2
PH - Filippine 2
ZA - Sudafrica 2
EC - Ecuador 1
IL - Israele 1
IR - Iran 1
KG - Kirghizistan 1
LV - Lettonia 1
MX - Messico 1
MY - Malesia 1
PE - Perù 1
PK - Pakistan 1
PL - Polonia 1
RO - Romania 1
TH - Thailandia 1
TM - Turkmenistan 1
UZ - Uzbekistan 1
Totale 10.280
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Città #
Fairfield 1.386
Chandler 916
Ashburn 749
Woodbridge 607
Seattle 597
Houston 500
Wilmington 455
Cambridge 453
Jacksonville 453
Singapore 318
Ann Arbor 276
Columbus 212
Princeton 171
San Mateo 159
New York 99
Beijing 93
Trento 81
San Diego 77
Helsinki 68
Dong Ket 55
Dearborn 50
Boardman 49
San Paolo di Civitate 45
Sofia 42
Jakarta 40
Lawrence 39
London 39
Fremont 38
Falls Church 35
Como 26
Los Angeles 25
Washington 25
Phoenix 21
Santa Clara 18
Bremen 17
Des Moines 17
Munich 15
Izmir 14
Norwalk 14
Mountain View 13
Riva Del Garda 13
Brno 12
Dallas 12
Genoa 10
Moscow 9
Kilburn 8
Hefei 7
Andover 6
Chicago 6
Chiswick 6
Deiva Marina 6
Fuzhou 6
Hong Kong 6
Pune 6
Tolentino 6
Altamura 5
Milan 5
Nanjing 5
Vienna 5
Colombo 4
Costa Mesa 4
Dublin 4
Hounslow 4
Prescot 4
Shanghai 4
Tappahannock 4
Annaba 3
Auckland 3
Bonndorf 3
Gunzenhausen 3
Islington 3
Kunming 3
Lappeenranta 3
Ottawa 3
Shenzhen 3
São Paulo 3
Tokai 3
Vigevano 3
Zhengzhou 3
Acton 2
Bend 2
Bolzano 2
Buccinasco 2
Buyeo-gun 2
Castello Molina di Fiemme 2
Chengdu 2
Chongqing 2
Clearwater 2
Düsseldorf 2
Edinburgh 2
Falkenstein 2
Florence 2
Hebei 2
Jinan 2
Manila 2
Melbourne 2
Monza 2
Nanchang 2
New Bedfont 2
Newark 2
Totale 8.555
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Nome #
Human transcription factors in yeast: the fruitful examples of P53 and NF-кB 258
Inherited determinants of early recurrent somatic mutations in prostate cancer 247
Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway 237
The ribonucleic complex HuR-MALAT1 represses CD133 expression and suppresses epithelial-mesenchymal transition in breast cancer 199
Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development 178
A highly specific SpCas9 variant is identified by in vivo screening in yeast 177
SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma 175
Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas 171
RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes 166
Whole-genome cartography of p53 response elements ranked on transactivation potential 164
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity 157
DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties 150
Functional analysis of CDKN2A/p16INK4a 5 ' UTR variants predisposing to melanoma 144
c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. 143
Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay 139
Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells 137
The 5'-untranslated region of p16INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding 132
Yeast as a chassis for developing functional assays to study human P53 132
Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay 127
Synthesis of 2,6-diamino-substituted purine derivatives and evaluation of cell cycle arrest in breast and colorectal cancer cells 127
A Cross-Platform Comparison of Affymetrix and Agilent Microarrays Reveals Discordant miRNA Expression in Lung Tumors of c-Raf Transgenic Mice 125
Regulatory Crosstalk of Doxorubicin, Estradiol and TNFα Combined Treatment in Breast Cancer-derived Cell Lines 120
LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β 118
Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code. 117
Discovery of a new small-molecule inhibitor of p53-MDM2 interaction using a yeast-based approach. 114
Contribution of yeast and plant research for improving human health. 113
A functional genetic study identifies HAND1 mutations in septation defects of the human heart. 113
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule 113
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. 111
P53 Family Members Modulate the Expression of PRODH, but Not PRODH2, via Intronic p53 Response Elements. 109
In-silico identification and functional validation of allele-dependent AR enhancers 108
p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system 107
MicroRNA-based, p53 dependent post-transcriptional circuits: mechanisms, targets and inter-individual variation 106
p53-directed translational control can shape and expand the universe of p53 target genes. 104
Α-mangostin and gambogic acid as potential inhibitors of the p53-MDM2 interaction revealed by a yeast approach. 103
EEC- and ADULT-associated TP63 mutations exhibit functional heterogeneity toward P63 responsive sequences. 103
JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. 103
Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. 102
Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson. 102
Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair. 101
Functional analysis of CDKN2A/p16INK4a 5'-UTR variants predisposing to melanoma 101
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts. 100
MicroRNA-based, p53 dependent post-transcriptional circuits: mechanisms, targets and inter-individual variation 99
Structural studies on mechanisms to activate mutant p53. 99
Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine. 99
TP53 Mutants in the Tower of Babel of Cancer Progression. 97
Identification of new p53 target microRNAs by bioinformatics and functional analysis 97
Translation control can shape TP53-dependent cell fate 96
The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound. 95
Transcriptional properties of feline p53 and its tumour-associated mutants: a yeast-based approach. 95
Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction. 95
The expanding universe of p53 targets 94
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes. 92
P63 modulates the expression of the WDFY2 gene which is implicated in cancer regulation and limb development 92
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics. 91
3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro. 91
Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation. 91
Apigenin rich-Limonium duriusculum (de Girard) Kuntze promotes apoptosis in HCT116 cancer cells 91
Functional analysis of CDKN2A 5'UTR variants associated with family history of melanoma 90
Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30 89
Identification of a novel TP53 germline mutation in a large Italian Li-Fraumeni syndrome Family. 88
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. 88
XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine. 88
A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network 87
The CDKN2A/p16(INK) (4a) 5'UTR sequence and translational regulation: impact of novel variants predisposing to melanoma 87
Transcriptional defect of an inherited NKX2-5 haplotype comprising a SNP, a nonsynonymous and a synonymous mutation, associated with human congenital heart disease. 86
High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells. 86
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation 86
Functional diversity in the gene network controlled by the master regulator p53 in humans. 84
The kinetics of p53-binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage. 83
More targets, more pathways and more clues for mutant p53. 82
Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system. 81
Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction 81
PRIMA-1 synergizes with adriamycin to induce cell death in non-small cell lung cancer cells. 80
PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells. 79
Regulation of human PTCH1b expression by different 5' untranslated region cis-regulatory elements 79
MDM2 SNP309 genotype influences survival of metastatic but not of localized neuroblastoma. 78
The structure formed by inverted repeats in p53 response elements determines the transactivation activity of p53 protein 78
SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy 78
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. 77
Increased risk of colorectal adenomas in Italian subjects carrying the p53 PIN3 A2-Pro72 haplotype. 77
Transcriptional functionality of germ line p53 mutants influences cancer phenotype 75
Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences 74
Functional evolution of the p53 regulatory network through its target response elements 74
The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes. 72
Cooperative interactions between p53 and NFκB enhance cell plasticity. 71
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. 68
Characterization of the p53 mutants ability to inhibit p73β transactivation using a yeast-based functional assay 67
Impact of MDM2 SNP309 genotype on progression and survival of stage 4 neuroblastoma. 66
The influence of quadruplex structure in proximity to P53 target sequences on the transactivation potential of p53 alpha isoforms 66
Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer 55
Potentiating the p53 network. 53
TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance 53
A selective p53 activator and anticancer agent to improve colorectal cancer therapy 53
Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent 52
DHX30 coordinates cytoplasmic translation and mitochondrial function contributing to cancer cell survival 50
The growing relevance of cap-independent translation initiation in cancer-related genes 41
LncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis 40
Rev1 and Polzeta influence toxicity and mutagenicity of Me-lex, a sequence selective N3-adenine methylating agent. 38
Tumour p53 mutations exhibit promoter selective dominance over wild type p53 38
Totale 10.285
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Categoria #
all - tutte 49.955
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 770
Totale 50.725
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/20201.762 0 0 0 0 245 164 327 280 349 183 100 114
2020/20212.213 68 390 244 231 193 180 111 119 98 177 174 228
2021/20221.340 67 190 18 53 53 40 60 230 108 100 140 281
2022/20231.873 311 247 45 281 165 271 9 116 223 18 109 78
2023/2024672 39 65 44 29 67 210 53 47 7 23 14 74
2024/2025863 25 18 159 529 132 0 0 0 0 0 0 0
Totale 10.631