IRIS
Inga, Alberto
 Distribuzione geografica
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Continente #
NA - Nord America 11.687
AS - Asia 3.290
EU - Europa 2.409
SA - Sud America 593
Continente sconosciuto - Info sul continente non disponibili 385
AF - Africa 74
OC - Oceania 14
Totale 18.452
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Nazione #
US - Stati Uniti d'America 11.548
SG - Singapore 1.402
VN - Vietnam 706
CN - Cina 573
BR - Brasile 482
RU - Federazione Russa 441
IT - Italia 405
SE - Svezia 250
FI - Finlandia 217
GB - Regno Unito 207
UA - Ucraina 193
DE - Germania 188
FR - Francia 150
LV - Lettonia 116
IN - India 91
KR - Corea 90
HK - Hong Kong 85
CA - Canada 82
ID - Indonesia 54
BD - Bangladesh 53
BG - Bulgaria 47
AR - Argentina 41
JP - Giappone 40
JO - Giordania 39
TR - Turchia 37
IQ - Iraq 33
MX - Messico 32
NL - Olanda 32
PL - Polonia 30
AT - Austria 26
ES - Italia 25
ZA - Sudafrica 23
CZ - Repubblica Ceca 19
CO - Colombia 18
EC - Ecuador 16
MA - Marocco 15
CL - Cile 13
GR - Grecia 12
PH - Filippine 12
PK - Pakistan 12
UZ - Uzbekistan 11
AU - Australia 10
IE - Irlanda 9
LT - Lituania 9
DZ - Algeria 8
JM - Giamaica 8
VE - Venezuela 8
AL - Albania 6
BE - Belgio 6
KE - Kenya 6
NP - Nepal 6
AO - Angola 5
CH - Svizzera 5
IL - Israele 5
PE - Perù 5
SA - Arabia Saudita 5
TT - Trinidad e Tobago 5
A2 - ???statistics.table.value.countryCode.A2??? 4
EG - Egitto 4
ET - Etiopia 4
KZ - Kazakistan 4
LK - Sri Lanka 4
MY - Malesia 4
NZ - Nuova Zelanda 4
PY - Paraguay 4
AE - Emirati Arabi Uniti 3
AZ - Azerbaigian 3
CR - Costa Rica 3
OM - Oman 3
TH - Thailandia 3
BH - Bahrain 2
BO - Bolivia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
EU - Europa 2
GA - Gabon 2
HN - Honduras 2
KG - Kirghizistan 2
LI - Liechtenstein 2
LU - Lussemburgo 2
NG - Nigeria 2
NO - Norvegia 2
QA - Qatar 2
SR - Suriname 2
UY - Uruguay 2
XK - ???statistics.table.value.countryCode.XK??? 2
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BJ - Benin 1
BQ - ???statistics.table.value.countryCode.BQ??? 1
BS - Bahamas 1
BY - Bielorussia 1
CG - Congo 1
CI - Costa d'Avorio 1
CY - Cipro 1
GD - Grenada 1
GG - Guernsey 1
HR - Croazia 1
HU - Ungheria 1
IR - Iran 1
Totale 18.065
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Città #
Fairfield 1.386
Ashburn 1.281
Chandler 916
Singapore 885
Woodbridge 607
Seattle 600
San Jose 524
Houston 518
Wilmington 457
Cambridge 453
Jacksonville 453
Dallas 413
Columbus 301
Santa Clara 281
Ann Arbor 276
Council Bluffs 228
Ho Chi Minh City 179
Moscow 179
Hanoi 173
Princeton 171
New York 166
San Mateo 159
Los Angeles 138
The Dalles 128
Beijing 125
Helsinki 120
Riga 116
Lauterbourg 98
Trento 91
Seoul 85
San Diego 77
Boardman 73
Hong Kong 72
Munich 68
São Paulo 63
London 60
Phoenix 57
Dong Ket 55
Chicago 53
Dearborn 50
Orem 47
Buffalo 45
San Paolo di Civitate 45
Da Nang 44
Sofia 44
Jakarta 41
Lawrence 39
Fremont 38
Milan 36
Montreal 36
Falls Church 35
Tokyo 32
Nuremberg 29
Washington 29
Haiphong 27
Warsaw 27
Como 26
Denver 23
North Bergen 23
Atlanta 22
Hefei 22
Rome 21
Toronto 20
Des Moines 18
Redondo Beach 18
Bremen 17
Chennai 17
Izmir 17
Belo Horizonte 16
Brno 16
Brooklyn 16
Frankfurt am Main 16
Norwalk 15
Shanghai 15
Stockholm 15
Turku 15
Falkenstein 14
Johannesburg 14
Rio de Janeiro 14
Mountain View 13
Mumbai 13
Poplar 13
Riva Del Garda 13
Genoa 12
Guangzhou 12
Vienna 12
Baghdad 11
Hải Dương 11
Salt Lake City 11
Amsterdam 10
Corinth 10
Elk Grove Village 10
Paris 10
Biên Hòa 9
Brasília 9
Manchester 9
Tashkent 9
Ankara 8
Dublin 8
Fuzhou 8
Totale 13.360
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Nome #
A highly specific SpCas9 variant is identified by in vivo screening in yeast 339
Inherited determinants of early recurrent somatic mutations in prostate cancer 337
Conserved Pseudoknots in lncRNA MEG3 Are Essential for Stimulation of the p53 Pathway 332
Human transcription factors in yeast: the fruitful examples of P53 and NF-кB 323
The ribonucleic complex HuR-MALAT1 represses CD133 expression and suppresses epithelial-mesenchymal transition in breast cancer 283
SLMP53-2 Restores Wild-Type-Like Function to Mutant p53 through Hsp70: Promising Activity in Hepatocellular Carcinoma 276
Decoding c-Myc networks of cell cycle and apoptosis regulated genes in a transgenic mouse model of papillary lung adenocarcinomas 273
RiboAbacus: a model trained on polyribosome images predicts ribosome density and translational efficiency from mammalian transcriptomes 245
Whole-genome cartography of p53 response elements ranked on transactivation potential 234
Functional analysis of a CDKN2A 5'UTR germline variant associated with pancreatic cancer development 233
Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity 222
A Cross-Platform Comparison of Affymetrix and Agilent Microarrays Reveals Discordant miRNA Expression in Lung Tumors of c-Raf Transgenic Mice 218
c-Myc targeted regulators of cell metabolism in a transgenic mouse model of papillary lung adenocarcinoma. 217
Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells 216
Quantitative Analysis of NF-κB Transactivation Specificity Using a Yeast-Based Functional Assay 213
MicroRNA-based, p53 dependent post-transcriptional circuits: mechanisms, targets and inter-individual variation 211
DIMP53-1: a novel small-molecule dual inhibitor of p53-MDM2/X interactions with multifunctional p53-dependent anticancer properties 211
Evolution of p53 transactivation specificity through the lens of a yeast-based functional assay 210
Functional analysis of CDKN2A/p16INK4a 5 ' UTR variants predisposing to melanoma 209
A functional genetic study identifies HAND1 mutations in septation defects of the human heart. 207
Synthesis of 2,6-diamino-substituted purine derivatives and evaluation of cell cycle arrest in breast and colorectal cancer cells 205
LncRNA EPR controls epithelial proliferation by coordinating Cdkn1a transcription and mRNA decay response to TGF-β 204
A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts. 203
Transactivation specificity is conserved among p53 family proteins and depends on a response element sequence code. 202
Allele-specific genomic data elucidate the role of somatic gain and copy-number neutral loss of heterozygosity in cancer 200
P53 Family Members Modulate the Expression of PRODH, but Not PRODH2, via Intronic p53 Response Elements. 195
Yeast as a chassis for developing functional assays to study human P53 192
The 5'-untranslated region of p16INK4a melanoma tumor suppressor acts as a cellular IRES, controlling mRNA translation under hypoxia through YBX1 binding 191
Discovery of a new small-molecule inhibitor of p53-MDM2 interaction using a yeast-based approach. 189
Apigenin rich-Limonium duriusculum (de Girard) Kuntze promotes apoptosis in HCT116 cancer cells 185
Translation control can shape TP53-dependent cell fate 185
The TP53 website: an integrative resource centre for the TP53 mutation database and TP53 mutant analysis. 184
Characterization of the p53 mutants ability to inhibit p73β transactivation using a yeast-based functional assay 180
Changing the p53 master regulatory network: ELEMENTary, my dear Mr Watson. 179
A single-nucleotide polymorphism in a half-binding site creates p53 and estrogen receptor control of vascular endothelial growth factor receptor 1. 178
Contribution of yeast and plant research for improving human health. 177
p53 transactivation and the impact of mutations, cofactors and small molecules using a simplified yeast-based screening system 176
3-Methyl-3-deazaadenine, a stable isostere of N3-methyl-adenine, is efficiently bypassed by replication in vivo and by transcription in vitro. 176
Regulatory Crosstalk of Doxorubicin, Estradiol and TNFα Combined Treatment in Breast Cancer-derived Cell Lines 174
The CDKN2A/p16(INK) (4a) 5'UTR sequence and translational regulation: impact of novel variants predisposing to melanoma 173
In-silico identification and functional validation of allele-dependent AR enhancers 172
Cooperative interactions between p53 and NFκB enhance cell plasticity. 170
Nutlin-Induced Apoptosis Is Specified by a Translation Program Regulated by PCBP2 and DHX30 169
A selective p53 activator and anticancer agent to improve colorectal cancer therapy 169
The coordinated p53 and estrogen receptor cis-regulation at an FLT1 promoter SNP is specific to genotoxic stress and estrogenic compound. 168
Dominant-negative features of mutant TP53 in germline carriers have limited impact on cancer outcomes. 168
A SNP in the flt-1 promoter integrates the VEGF system into the p53 transcriptional network 168
JNK-NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress. 168
SMN-primed ribosomes modulate the translation of transcripts related to spinal muscular atrophy 168
EEC- and ADULT-associated TP63 mutations exhibit functional heterogeneity toward P63 responsive sequences. 167
Functional analysis of CDKN2A/p16INK4a 5'-UTR variants predisposing to melanoma 167
Interaction between p53 and estradiol pathways in transcriptional responses to chemotherapeutics. 166
p53-directed translational control can shape and expand the universe of p53 target genes. 165
Functional analysis of CDKN2A 5'UTR variants associated with family history of melanoma 163
Structure of p73 DNA-binding domain tetramer modulates p73 transactivation. 162
MicroRNA-based, p53 dependent post-transcriptional circuits: mechanisms, targets and inter-individual variation 161
Mutagenicity of N3-methyladenine: a multi-translesion polymerase affair. 161
Altered-function p53 missense mutations identified in breast cancers can have subtle effects on transactivation. 160
Reactivation of wild-type and mutant p53 by tryptophanolderived oxazoloisoindolinone SLMP53-1, a novel anticancer small-molecule 159
Identification of new p53 target microRNAs by bioinformatics and functional analysis 157
Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine. 157
Α-mangostin and gambogic acid as potential inhibitors of the p53-MDM2 interaction revealed by a yeast approach. 156
High frequency of genomic deletions induced by Me-lex, a sequence selective N3-adenine methylating agent, at the Hprt locus in Chinese hamster ovary cells. 155
TP53 Mutants in the Tower of Babel of Cancer Progression. 154
LncRNA EPR regulates intestinal mucus production and protects against inflammation and tumorigenesis 149
P63 modulates the expression of the WDFY2 gene which is implicated in cancer regulation and limb development 149
Transcriptional properties of feline p53 and its tumour-associated mutants: a yeast-based approach. 145
Influences of base excision repair defects on the lethality and mutagenicity induced by Me-lex, a sequence-selective N3-adenine methylating agent 144
The expanding universe of p53 targets 143
Studying RNP Composition with RIP 140
More targets, more pathways and more clues for mutant p53. 138
Oxazoloisoindolinones with in vitro antitumor activity selectively activate a p53-pathway through potential inhibition of the p53-MDM2 interaction. 138
Structural studies on mechanisms to activate mutant p53. 137
DHX30 coordinates cytoplasmic translation and mitochondrial function contributing to cancer cell survival 137
The structure formed by inverted repeats in p53 response elements determines the transactivation activity of p53 protein 135
Transactivation by partial function P53 family mutants is increased by the presence of G-quadruplexes at a promoter site 133
Functionally distinct polymorphic sequences in the human genome that are targets for p53 transactivation 132
TranSNPs: A class of functional SNPs affecting mRNA translation potential revealed by fraction-based allelic imbalance 131
Transcriptional defect of an inherited NKX2-5 haplotype comprising a SNP, a nonsynonymous and a synonymous mutation, associated with human congenital heart disease. 127
Identification of a novel TP53 germline mutation in a large Italian Li-Fraumeni syndrome Family. 127
PRIMA-1 cytotoxicity correlates with nucleolar localization and degradation of mutant p53 in breast cancer cells. 127
Estrogen receptor acting in cis enhances WT and mutant p53 transactivation at canonical and noncanonical p53 target sequences 125
Noncanonical DNA motifs as transactivation targets by wild type and mutant p53. 124
The kinetics of p53-binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage. 123
∆N-P63α and TA-P63α exhibit intrinsic differences in transactivation specificities that depend on distinct features of DNA target sites. 123
Compartment-specific and ELAVL1-coordinated regulation of intronic polyadenylation isoforms by doxorubicin 122
Functional diversity in the gene network controlled by the master regulator p53 in humans. 122
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 120
Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system. 120
XRCC1 deficiency influences the cytotoxicity and the genomic instability induced by Me-lex, a specific inducer of N3-methyladenine. 120
MDM2 SNP309 genotype influences survival of metastatic but not of localized neuroblastoma. 117
Increased risk of colorectal adenomas in Italian subjects carrying the p53 PIN3 A2-Pro72 haplotype. 116
Functional evolution of the p53 regulatory network through its target response elements 115
Tumour p53 mutations exhibit promoter selective dominance over wild type p53 114
Enhanced cytotoxicity of prenylated chalcone against tumour cells via disruption of the p53-MDM2 interaction 112
The biological impact of the human master regulator p53 can be altered by mutations that change the spectrum and expression of its target genes. 109
PRIMA-1 synergizes with adriamycin to induce cell death in non-small cell lung cancer cells. 109
The influence of quadruplex structure in proximity to P53 target sequences on the transactivation potential of p53 alpha isoforms 109
Regulation of human PTCH1b expression by different 5' untranslated region cis-regulatory elements 107
Transcriptional functionality of germ line p53 mutants influences cancer phenotype 106
Totale 17.232
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Categoria #
all - tutte 76.182
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 1.235
Totale 77.417
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/20221.083 0 0 18 53 53 40 60 230 108 100 140 281
2022/20231.873 311 247 45 281 165 271 9 116 223 18 109 78
2023/2024672 39 65 44 29 67 210 53 47 7 23 14 74
2024/20252.704 25 18 159 529 173 330 163 209 280 461 176 181
2025/20265.564 393 157 733 693 628 368 1.145 180 455 469 201 142
2026/2027416 104 283 29 0 0 0 0 0 0 0 0 0
Totale 18.452