IRIS
Biasini, Emiliano
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
NA - Nord America 3.820
EU - Europa 645
AS - Asia 529
Continente sconosciuto - Info sul continente non disponibili 6
SA - Sud America 4
OC - Oceania 2
AF - Africa 1
Totale 5.007
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 3.810
SG - Singapore 270
IT - Italia 231
CN - Cina 148
FI - Finlandia 100
SE - Svezia 89
GB - Regno Unito 75
DE - Germania 51
JO - Giordania 42
RU - Federazione Russa 39
VN - Vietnam 24
BG - Bulgaria 20
ID - Indonesia 14
TR - Turchia 14
CA - Canada 8
NL - Olanda 8
UA - Ucraina 8
IN - India 5
EU - Europa 4
IE - Irlanda 4
JP - Giappone 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AU - Australia 2
AZ - Azerbaigian 2
BE - Belgio 2
BR - Brasile 2
BY - Bielorussia 2
CZ - Repubblica Ceca 2
FR - Francia 2
GR - Grecia 2
LU - Lussemburgo 2
MX - Messico 2
AE - Emirati Arabi Uniti 1
AT - Austria 1
BO - Bolivia 1
DK - Danimarca 1
ES - Italia 1
HK - Hong Kong 1
HU - Ungheria 1
IQ - Iraq 1
KR - Corea 1
LA - Repubblica Popolare Democratica del Laos 1
LT - Lituania 1
LV - Lettonia 1
MA - Marocco 1
PK - Pakistan 1
PL - Polonia 1
RO - Romania 1
SA - Arabia Saudita 1
VE - Venezuela 1
Totale 5.007
Salva come PNG Salva come JPEG
Città #
Fairfield 562
Chandler 505
Ashburn 276
Woodbridge 237
Seattle 230
San Mateo 222
Houston 205
Singapore 203
Cambridge 188
Wilmington 174
Ann Arbor 163
Santa Clara 144
Columbus 123
Princeton 113
Jacksonville 69
Helsinki 64
Beijing 46
Trento 39
San Diego 38
Dearborn 34
New York 33
Moscow 30
Como 26
San Paolo di Civitate 22
Boardman 20
London 20
Fremont 19
Sofia 19
Dong Ket 14
Jakarta 14
Izmir 13
Norwalk 12
Munich 11
Tolentino 10
Nanjing 9
Bassano del Grappa 7
Des Moines 7
Perugia 7
Shanghai 7
Washington 7
Milan 6
Toronto 6
Bonndorf 5
Costa Mesa 5
Altamura 4
Bremen 4
Dallas 4
Dublin 4
Los Angeles 4
Naples 4
Rome 4
Verona 4
Augusta 3
Berlin 3
Bologna 3
Casalecchio di Reno 3
Frankfurt am Main 3
Guangzhou 3
Kilburn 3
Padova 3
Amsterdam 2
Andover 2
Athens 2
Augsburg 2
Baku 2
Brussels 2
Catania 2
Cernusco sul Naviglio 2
Chengdu 2
Chiswick 2
Foligno 2
Groningen 2
Hangzhou 2
Hefei 2
Hounslow 2
Isesaki 2
Jinan 2
Kunming 2
Leipzig 2
Messina 2
Minsk 2
Nanchang 2
Ottawa 2
Parma 2
Phoenix 2
Prague 2
Riva Del Garda 2
Rovereto 2
Schio 2
Tesero 2
Velletri 2
Volgograd 2
Wandsworth 2
Adelaide 1
Allen 1
Baotou 1
Bari 1
Bastia umbra 1
Caivano 1
Camerino 1
Totale 4.093
Salva come PNG Salva come JPEG
Nome #
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 177
Regulation of HuR structure and function by dihydrotanshinone-I 170
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 161
Full atomistic model of prion structure and conversion 155
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 128
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 126
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo 122
Pharmacological inactivation of the prion protein by targeting a folding intermediate 119
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo 116
Acute Neurotoxicity Models of Prion Disease 112
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells 110
Mutant prion protein expression is associated with an alteration of the rab GDP dissociation inhibitor α (GDI)/rab11 pathway 109
Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: A novel pharmacological strategy against brain injury 107
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein 96
Pharmacological Agents Targeting the Cellular Prion Protein 96
The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers 95
All-Atom Simulation of HET-s Prion Replication 92
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention 91
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide 91
Common therapeutic strategies for prion and Alzheimer's diseases 90
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 90
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity 89
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein 89
Ok google, how could i design therapeutics against prion diseases? 89
The N-terminal, polybasic region of PrP C dictates the efficiency of prion propagation by binding to PrP Sc 88
null 86
The N-terminal, polybasic region is critical for prion protein neuroprotective activity 86
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 84
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity 83
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity 83
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis 83
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells 81
Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities 80
Understanding prion structure and conversion 80
Proteasome inhibition and aggregation in Parkinson's disease: A comparative study in untransfected and transfected cells 79
Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases 78
Immunopurification of pathological prion protein aggregates 74
The cellular prion protein beyond prion diseases 74
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice 73
A designer chaperone against prion diseases 72
Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans 71
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation 71
Generation, optimization and characterization of novel anti-prion compounds 67
Non-infectious aggregates of the prion protein react with several PrP Sc-directed antibodies 66
Modeling PrPSc Generation Through Deformed Templating 66
null 62
Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion 60
Targeting the cellular prion protein to treat neurodegeneration 59
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases 58
Role of lipid rafts and GM1 in the segregation and processing of prion protein 55
Prion protein ligands as therapeutic agents for neurodegenerative disorders 50
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia 50
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention 49
Ion channels induced by the prion protein: Mediators of neurotoxicity 41
A Method for Identifying Intermediates 35
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 34
Functional, pathogenic, and pharmacological roles of protein folding intermediates 33
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse 33
Redox regulation of cyclophilin A by glutathionylation 33
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains 31
Infectious and pathogenic forms of PrP 31
Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity 29
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies 22
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan 20
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of sars-cov-2 infectivity 20
Gene expression profiling in trigeminal ganglia from Cntnap2-/- and Shank3b-/- mouse models of autism spectrum disorder 19
null 11
Prion protein at the crossroads of physiology and disease 9
Small moleules inducing the degradation of the cellular prion protein 6
Small molecules inducing the degradation of the cellular prion protein 4
Totale 5.199
Salva come PNG Salva come JPEG
Categoria #
all - tutte 28.617
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 580
selected - selezionate 0
volume - volumi 869
Totale 30.066
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/2020580 0 0 0 0 0 77 111 100 144 79 41 28
2020/2021743 33 52 28 53 29 108 51 83 50 112 98 46
2021/2022852 52 217 7 33 8 21 35 190 35 63 99 92
2022/2023997 102 129 6 139 110 151 7 69 163 21 51 49
2023/2024421 21 52 23 20 36 86 48 38 4 14 12 67
2024/2025733 11 15 131 285 122 169 0 0 0 0 0 0
Totale 5.199