IRIS
Biasini, Emiliano
 Distribuzione geografica
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Continente #
NA - Nord America 5.523
AS - Asia 2.243
EU - Europa 1.515
SA - Sud America 305
AF - Africa 40
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
Totale 9.635
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Nazione #
US - Stati Uniti d'America 5.452
SG - Singapore 995
VN - Vietnam 447
IT - Italia 393
CN - Cina 374
RU - Federazione Russa 302
BR - Brasile 233
FI - Finlandia 149
DE - Germania 128
GB - Regno Unito 118
SE - Svezia 102
KR - Corea 85
FR - Francia 84
LV - Lettonia 70
HK - Hong Kong 57
IN - India 51
JO - Giordania 48
NL - Olanda 43
CA - Canada 39
BD - Bangladesh 31
AR - Argentina 27
ID - Indonesia 27
TR - Turchia 24
JP - Giappone 23
PL - Polonia 23
BG - Bulgaria 21
MX - Messico 19
IQ - Iraq 16
ES - Italia 15
ZA - Sudafrica 12
PH - Filippine 11
UA - Ucraina 11
CO - Colombia 10
AZ - Azerbaigian 9
LT - Lituania 9
MA - Marocco 9
SA - Arabia Saudita 9
EC - Ecuador 8
PY - Paraguay 8
AT - Austria 7
PK - Pakistan 7
VE - Venezuela 7
BE - Belgio 6
CZ - Repubblica Ceca 6
PE - Perù 6
UZ - Uzbekistan 6
IE - Irlanda 5
AE - Emirati Arabi Uniti 4
EG - Egitto 4
ET - Etiopia 4
EU - Europa 4
AU - Australia 3
BY - Bielorussia 3
GR - Grecia 3
HN - Honduras 3
HR - Croazia 3
KE - Kenya 3
TH - Thailandia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BO - Bolivia 2
CH - Svizzera 2
CL - Cile 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
LB - Libano 2
LU - Lussemburgo 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
PT - Portogallo 2
RO - Romania 2
TN - Tunisia 2
UY - Uruguay 2
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CI - Costa d'Avorio 1
CR - Costa Rica 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
GT - Guatemala 1
HU - Ungheria 1
IL - Israele 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
NG - Nigeria 1
PA - Panama 1
PS - Palestinian Territory 1
QA - Qatar 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
ZW - Zimbabwe 1
Totale 9.635
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Città #
Ashburn 597
Singapore 593
Fairfield 562
Chandler 501
San Jose 331
Woodbridge 238
Seattle 232
San Mateo 222
Houston 213
Cambridge 188
Ann Arbor 178
Wilmington 177
Santa Clara 159
Moscow 152
Dallas 140
Columbus 123
Princeton 113
Ho Chi Minh City 112
Hanoi 107
Los Angeles 94
Beijing 90
Helsinki 89
The Dalles 87
Seoul 80
New York 78
Riga 70
Jacksonville 69
Trento 62
Lauterbourg 58
Council Bluffs 52
Munich 51
Hong Kong 48
Orem 45
San Diego 40
Dearborn 34
Buffalo 32
Da Nang 28
St Louis 27
Chicago 26
Como 26
London 26
São Paulo 26
North Bergen 24
Boardman 22
San Paolo di Civitate 22
Sofia 20
Denver 19
Fremont 19
Haiphong 19
Hefei 19
Warsaw 19
Jakarta 16
Tokyo 16
Montreal 15
Rome 15
Toronto 15
Dong Ket 14
Izmir 13
Perugia 13
Salt Lake City 13
Turku 13
Bologna 12
Chennai 12
Norwalk 12
Brooklyn 11
Cavalese 11
Falkenstein 11
Frankfurt am Main 11
Stockholm 11
Amsterdam 10
Lappeenranta 10
Ninh Bình 10
Shanghai 10
Tolentino 10
Atlanta 9
Biên Hòa 9
Elk Grove Village 9
Hillsboro 9
Milan 9
Nanjing 9
Poplar 9
Washington 9
Baku 8
Can Tho 8
Des Moines 8
Hải Dương 8
Nuremberg 8
San Francisco 8
Bassano del Grappa 7
Bến Tre 7
Curitiba 7
Guangzhou 7
Johannesburg 7
Kensington 7
Mexico City 7
Naples 7
Rio de Janeiro 7
Amman 6
Baghdad 6
Boston 6
Totale 6.844
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Nome #
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 295
Regulation of HuR structure and function by dihydrotanshinone-I 252
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 241
Full atomistic model of prion structure and conversion 240
Pharmacological inactivation of the prion protein by targeting a folding intermediate 238
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 210
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 208
Acute Neurotoxicity Models of Prion Disease 193
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo 190
Understanding prion structure and conversion 186
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo 185
All-Atom Simulation of HET-s Prion Replication 178
Mutant prion protein expression is associated with an alteration of the rab GDP dissociation inhibitor α (GDI)/rab11 pathway 177
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells 177
Pharmacological Agents Targeting the Cellular Prion Protein 170
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 167
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis 166
Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: A novel pharmacological strategy against brain injury 163
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention 163
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide 162
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein 155
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity 155
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 153
Ok google, how could i design therapeutics against prion diseases? 153
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity 152
Common therapeutic strategies for prion and Alzheimer's diseases 150
The cellular prion protein beyond prion diseases 146
The N-terminal, polybasic region of PrP C dictates the efficiency of prion propagation by binding to PrP Sc 142
Enantiomers of the prion protein degrader SM875: Production and configurational assignment, in silico analysis and in vitro evaluation 140
Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases 139
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity 138
Modeling PrPSc Generation Through Deformed Templating 137
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention 135
The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers 134
Prion protein ligands as therapeutic agents for neurodegenerative disorders 133
The N-terminal, polybasic region is critical for prion protein neuroprotective activity 132
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia 132
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains 131
Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities 130
A designer chaperone against prion diseases 128
Non-infectious aggregates of the prion protein react with several PrP Sc-directed antibodies 127
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells 124
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse 124
Generation, optimization and characterization of novel anti-prion compounds 120
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 117
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases 117
Proteasome inhibition and aggregation in Parkinson's disease: A comparative study in untransfected and transfected cells 113
Role of lipid rafts and GM1 in the segregation and processing of prion protein 112
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein 111
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation 109
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan 100
Immunopurification of pathological prion protein aggregates 100
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice 98
A Method for Identifying Intermediates 96
Functional, pathogenic, and pharmacological roles of protein folding intermediates 95
Gene expression profiling in trigeminal ganglia from Cntnap2-/- and Shank3b-/- mouse models of autism spectrum disorder 93
Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans 93
Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity 93
Targeting the cellular prion protein to treat neurodegeneration 87
null 86
Redox regulation of cyclophilin A by glutathionylation 85
Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion 83
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies 82
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint 80
Ion channels induced by the prion protein: Mediators of neurotoxicity 72
Small moleules inducing the degradation of the cellular prion protein 69
Prion protein promotes copper toxicity in Wilson disease 68
null 62
Infectious and pathogenic forms of PrP 61
Small molecules inducing the degradation of the cellular prion protein 60
Mapping cryptic phosphorylation sites in the human proteome 60
The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens 52
Therapeutic Trajectories in Human Prion Diseases 47
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of sars-cov-2 infectivity 44
Beneficial effects of synthetic torpor in a fast-progressing mouse model of amyotrophic lateral sclerosis 33
Prion protein at the crossroads of physiology and disease 9
Totale 9.858
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Categoria #
all - tutte 41.626
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 1.239
selected - selezionate 0
volume - volumi 1.356
Totale 44.221
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021144 0 0 0 0 0 0 0 0 0 0 98 46
2021/2022852 52 217 7 33 8 21 35 190 35 63 99 92
2022/2023990 102 129 6 138 108 150 7 69 163 21 49 48
2023/2024417 20 52 23 20 36 86 48 37 4 14 12 65
2024/20251.707 11 15 130 280 121 169 38 80 233 340 145 145
2025/20263.696 269 118 377 606 415 305 715 111 337 299 144 0
Totale 9.858