IRIS
Biasini, Emiliano
 Distribuzione geografica
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Continente #
NA - Nord America 6.301
AS - Asia 2.304
EU - Europa 1.619
SA - Sud America 327
Continente sconosciuto - Info sul continente non disponibili 229
AF - Africa 41
OC - Oceania 3
Totale 10.824
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Nazione #
US - Stati Uniti d'America 6.185
SG - Singapore 1.001
VN - Vietnam 447
IT - Italia 445
CN - Cina 378
RU - Federazione Russa 302
BR - Brasile 245
FI - Finlandia 149
SE - Svezia 133
DE - Germania 129
GB - Regno Unito 126
KR - Corea 86
FR - Francia 85
LV - Lettonia 70
BD - Bangladesh 67
CA - Canada 58
HK - Hong Kong 58
IN - India 52
JO - Giordania 48
NL - Olanda 48
ID - Indonesia 33
AR - Argentina 31
TR - Turchia 25
JP - Giappone 23
PL - Polonia 23
MX - Messico 22
BG - Bulgaria 21
ES - Italia 17
IQ - Iraq 16
UA - Ucraina 13
PH - Filippine 12
ZA - Sudafrica 12
CO - Colombia 11
VE - Venezuela 10
AZ - Azerbaigian 9
EC - Ecuador 9
LT - Lituania 9
MA - Marocco 9
SA - Arabia Saudita 9
PY - Paraguay 8
AT - Austria 7
PK - Pakistan 7
BE - Belgio 6
CR - Costa Rica 6
CZ - Repubblica Ceca 6
HN - Honduras 6
PE - Perù 6
UZ - Uzbekistan 6
IE - Irlanda 5
TT - Trinidad e Tobago 5
AE - Emirati Arabi Uniti 4
BY - Bielorussia 4
EG - Egitto 4
ET - Etiopia 4
EU - Europa 4
JM - Giamaica 4
AU - Australia 3
CH - Svizzera 3
CL - Cile 3
GR - Grecia 3
GT - Guatemala 3
HR - Croazia 3
KE - Kenya 3
MY - Malesia 3
SV - El Salvador 3
TH - Thailandia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BO - Bolivia 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
KG - Kirghizistan 2
LB - Libano 2
LU - Lussemburgo 2
NP - Nepal 2
OM - Oman 2
PS - Palestinian Territory 2
PT - Portogallo 2
RO - Romania 2
TN - Tunisia 2
UY - Uruguay 2
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
BH - Bahrain 1
CG - Congo 1
CI - Costa d'Avorio 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
HU - Ungheria 1
IL - Israele 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
NG - Nigeria 1
NI - Nicaragua 1
PA - Panama 1
Totale 10.597
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Città #
Ashburn 703
Singapore 597
Fairfield 562
Chandler 501
San Jose 428
Woodbridge 239
Seattle 232
San Mateo 222
Houston 215
Cambridge 188
Ann Arbor 178
Santa Clara 177
Wilmington 177
Columbus 176
Moscow 152
Dallas 148
Council Bluffs 125
Princeton 113
Ho Chi Minh City 112
Hanoi 107
Los Angeles 104
Beijing 90
Helsinki 89
The Dalles 87
New York 84
Seoul 81
Riga 70
Jacksonville 69
Trento 63
Lauterbourg 58
Munich 51
Hong Kong 49
Orem 46
San Diego 41
Buffalo 34
Dearborn 34
Boardman 29
Chicago 29
Phoenix 29
Da Nang 28
São Paulo 28
St Louis 27
Como 26
London 26
North Bergen 24
San Paolo di Civitate 22
Sofia 20
Denver 19
Fremont 19
Haiphong 19
Hefei 19
Milan 19
Toronto 19
Warsaw 19
Rome 18
Montreal 17
Jakarta 16
Tokyo 16
Brooklyn 15
Dong Ket 14
Atlanta 13
Izmir 13
Perugia 13
Salt Lake City 13
Turku 13
Bologna 12
Chennai 12
Norwalk 12
Shanghai 12
Cavalese 11
Elk Grove Village 11
Falkenstein 11
Frankfurt am Main 11
Stockholm 11
Amsterdam 10
Lappeenranta 10
Ninh Bình 10
Tolentino 10
Washington 10
Biên Hòa 9
Boston 9
Hillsboro 9
Mexico City 9
Nanjing 9
Naples 9
Poplar 9
San Francisco 9
Baku 8
Can Tho 8
Des Moines 8
Hải Dương 8
Nuremberg 8
Rio de Janeiro 8
Bassano del Grappa 7
Bến Tre 7
Curitiba 7
Guangzhou 7
Johannesburg 7
Kensington 7
Secaucus 7
Totale 7.306
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Nome #
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 315
Pharmacological inactivation of the prion protein by targeting a folding intermediate 264
Regulation of HuR structure and function by dihydrotanshinone-I 263
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 261
Full atomistic model of prion structure and conversion 253
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 233
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 224
Acute Neurotoxicity Models of Prion Disease 214
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo 209
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo 199
Understanding prion structure and conversion 193
All-Atom Simulation of HET-s Prion Replication 189
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells 188
Mutant prion protein expression is associated with an alteration of the rab GDP dissociation inhibitor α (GDI)/rab11 pathway 185
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity 181
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide 181
Pharmacological Agents Targeting the Cellular Prion Protein 180
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 178
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis 175
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein 172
Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: A novel pharmacological strategy against brain injury 172
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 171
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention 170
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity 161
Ok google, how could i design therapeutics against prion diseases? 161
Prion protein ligands as therapeutic agents for neurodegenerative disorders 160
Common therapeutic strategies for prion and Alzheimer's diseases 158
Modeling PrPSc Generation Through Deformed Templating 157
Enantiomers of the prion protein degrader SM875: Production and configurational assignment, in silico analysis and in vitro evaluation 154
The cellular prion protein beyond prion diseases 154
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention 153
The N-terminal, polybasic region of PrP C dictates the efficiency of prion propagation by binding to PrP Sc 150
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia 148
The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers 147
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity 147
A designer chaperone against prion diseases 147
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains 146
The N-terminal, polybasic region is critical for prion protein neuroprotective activity 145
Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases 145
Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities 137
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells 134
Generation, optimization and characterization of novel anti-prion compounds 134
Non-infectious aggregates of the prion protein react with several PrP Sc-directed antibodies 133
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse 131
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 129
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases 126
Proteasome inhibition and aggregation in Parkinson's disease: A comparative study in untransfected and transfected cells 123
Role of lipid rafts and GM1 in the segregation and processing of prion protein 120
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein 118
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan 115
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation 114
Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity 110
Immunopurification of pathological prion protein aggregates 109
Gene expression profiling in trigeminal ganglia from Cntnap2-/- and Shank3b-/- mouse models of autism spectrum disorder 108
Functional, pathogenic, and pharmacological roles of protein folding intermediates 105
A Method for Identifying Intermediates 105
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice 104
Prion protein promotes copper toxicity in Wilson disease 101
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies 99
Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans 97
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint 95
Targeting the cellular prion protein to treat neurodegeneration 95
Redox regulation of cyclophilin A by glutathionylation 94
Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion 91
Small moleules inducing the degradation of the cellular prion protein 90
null 86
Ion channels induced by the prion protein: Mediators of neurotoxicity 83
Therapeutic Trajectories in Human Prion Diseases 76
Mapping cryptic phosphorylation sites in the human proteome 73
Infectious and pathogenic forms of PrP 73
Small molecules inducing the degradation of the cellular prion protein 70
The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens 65
null 62
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of sars-cov-2 infectivity 56
Beneficial effects of synthetic torpor in a fast-progressing mouse model of amyotrophic lateral sclerosis 51
Prion protein at the crossroads of physiology and disease 9
Totale 10.824
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Categoria #
all - tutte 46.673
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 1.506
selected - selezionate 0
volume - volumi 1.579
Totale 49.758
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022576 0 0 0 33 8 21 35 190 35 63 99 92
2022/2023990 102 129 6 138 108 150 7 69 163 21 49 48
2023/2024417 20 52 23 20 36 86 48 37 4 14 12 65
2024/20251.707 11 15 130 280 121 169 38 80 233 340 145 145
2025/20263.879 269 118 377 606 415 305 715 111 337 299 196 131
2026/2027783 116 174 284 209 0 0 0 0 0 0 0 0
Totale 10.824