IRIS
Biasini, Emiliano
 Distribuzione geografica
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Continente #
NA - Nord America 3.463
EU - Europa 534
AS - Asia 199
Continente sconosciuto - Info sul continente non disponibili 6
SA - Sud America 3
OC - Oceania 2
Totale 4.207
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Nazione #
US - Stati Uniti d'America 3.457
IT - Italia 193
FI - Finlandia 94
SE - Svezia 89
CN - Cina 77
GB - Regno Unito 71
JO - Giordania 42
SG - Singapore 35
DE - Germania 34
VN - Vietnam 24
BG - Bulgaria 20
TR - Turchia 14
UA - Ucraina 8
NL - Olanda 6
CA - Canada 5
EU - Europa 4
IE - Irlanda 4
RU - Federazione Russa 4
IN - India 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AU - Australia 2
BR - Brasile 2
BY - Bielorussia 2
FR - Francia 2
LU - Lussemburgo 2
AT - Austria 1
DK - Danimarca 1
GR - Grecia 1
IQ - Iraq 1
JP - Giappone 1
KR - Corea 1
MX - Messico 1
PK - Pakistan 1
PL - Polonia 1
RO - Romania 1
VE - Venezuela 1
Totale 4.207
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Città #
Fairfield 562
Chandler 505
Ashburn 271
Woodbridge 237
Seattle 230
San Mateo 222
Houston 205
Cambridge 188
Wilmington 174
Ann Arbor 163
Princeton 113
Jacksonville 69
Helsinki 59
Beijing 46
San Diego 38
Trento 35
Dearborn 34
New York 31
Como 26
San Paolo di Civitate 22
Fremont 19
Sofia 19
London 18
Dong Ket 14
Izmir 13
Norwalk 12
Tolentino 10
Des Moines 7
Nanjing 7
Perugia 7
Washington 7
Bonndorf 5
Costa Mesa 5
Toronto 5
Altamura 4
Bremen 4
Dublin 4
Milan 4
Shanghai 4
Augusta 3
Bassano del Grappa 3
Berlin 3
Casalecchio di Reno 3
Kilburn 3
Los Angeles 3
Amsterdam 2
Andover 2
Augsburg 2
Catania 2
Cernusco sul Naviglio 2
Chiswick 2
Foligno 2
Groningen 2
Guangzhou 2
Hangzhou 2
Hefei 2
Hounslow 2
Jinan 2
Kunming 2
Messina 2
Minsk 2
Nanchang 2
Naples 2
Padova 2
Parma 2
Phoenix 2
Riva Del Garda 2
Rovereto 2
Schio 2
Singapore 2
Verona 2
Wandsworth 2
Adelaide 1
Allen 1
Athens 1
Baotou 1
Bastia umbra 1
Boardman 1
Caivano 1
Camerino 1
Capriate San Gervasio 1
Carol Stream 1
Catanzaro 1
Changchun 1
Chengdu 1
Chicago 1
Conegliano 1
Distrito Federal 1
Easton 1
Falkenstein 1
Falls Church 1
Farra Di Soligo 1
Florence 1
Fontanelle 1
Frankfurt am Main 1
Hebei 1
Islamabad 1
La Canada Flintridge 1
Lappeenranta 1
Las Vegas 1
Totale 3.498
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Nome #
Regulation of HuR structure and function by dihydrotanshinone-I 155
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 152
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 142
Full atomistic model of prion structure and conversion 134
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 112
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo 110
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo 107
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 107
Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: A novel pharmacological strategy against brain injury 98
Mutant prion protein expression is associated with an alteration of the rab GDP dissociation inhibitor α (GDI)/rab11 pathway 98
Acute Neurotoxicity Models of Prion Disease 98
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells 97
The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers 87
null 86
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein 85
Pharmacological Agents Targeting the Cellular Prion Protein 85
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 83
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention 82
Common therapeutic strategies for prion and Alzheimer's diseases 81
The N-terminal, polybasic region is critical for prion protein neuroprotective activity 81
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein 79
Pharmacological inactivation of the prion protein by targeting a folding intermediate 79
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity 77
The N-terminal, polybasic region of PrP C dictates the efficiency of prion propagation by binding to PrP Sc 77
Ok google, how could i design therapeutics against prion diseases? 77
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide 77
Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases 74
All-Atom Simulation of HET-s Prion Replication 74
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells 72
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity 72
Proteasome inhibition and aggregation in Parkinson's disease: A comparative study in untransfected and transfected cells 71
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity 71
Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities 70
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice 68
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 68
Immunopurification of pathological prion protein aggregates 67
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis 66
Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans 63
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation 63
The cellular prion protein beyond prion diseases 63
null 62
Non-infectious aggregates of the prion protein react with several PrP Sc-directed antibodies 60
A designer chaperone against prion diseases 59
Understanding prion structure and conversion 59
Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion 54
Modeling PrPSc Generation Through Deformed Templating 53
Generation, optimization and characterization of novel anti-prion compounds 53
Targeting the cellular prion protein to treat neurodegeneration 52
Role of lipid rafts and GM1 in the segregation and processing of prion protein 48
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases 46
Prion protein ligands as therapeutic agents for neurodegenerative disorders 38
Ion channels induced by the prion protein: Mediators of neurotoxicity 36
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia 32
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention 30
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse 24
A Method for Identifying Intermediates 24
Infectious and pathogenic forms of PrP 22
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 21
Redox regulation of cyclophilin A by glutathionylation 20
Functional, pathogenic, and pharmacological roles of protein folding intermediates 17
Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity 16
null 11
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies 9
Prion protein at the crossroads of physiology and disease 9
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of sars-cov-2 infectivity 9
Gene expression profiling in trigeminal ganglia from Cntnap2-/- and Shank3b-/- mouse models of autism spectrum disorder 8
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains 6
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan 1
Totale 4.387
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Categoria #
all - tutte 23.021
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 370
selected - selezionate 0
volume - volumi 645
Totale 24.036
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019242 0 0 0 0 0 0 0 0 0 0 132 110
2019/2020920 49 32 58 110 91 77 111 100 144 79 41 28
2020/2021743 33 52 28 53 29 108 51 83 50 112 98 46
2021/2022852 52 217 7 33 8 21 35 190 35 63 99 92
2022/2023997 102 129 6 139 110 151 7 69 163 21 51 49
2023/2024342 21 52 23 20 36 86 48 38 4 14 0 0
Totale 4.387