IRIS
Biasini, Emiliano
 Distribuzione geografica
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Continente #
NA - Nord America 5.683
AS - Asia 2.281
EU - Europa 1.585
SA - Sud America 314
AF - Africa 40
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 3
Totale 9.912
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Nazione #
US - Stati Uniti d'America 5.595
SG - Singapore 997
VN - Vietnam 447
IT - Italia 429
CN - Cina 375
RU - Federazione Russa 302
BR - Brasile 239
FI - Finlandia 149
DE - Germania 128
SE - Svezia 127
GB - Regno Unito 119
KR - Corea 86
FR - Francia 84
LV - Lettonia 70
BD - Bangladesh 63
HK - Hong Kong 58
IN - India 52
JO - Giordania 48
CA - Canada 47
NL - Olanda 47
AR - Argentina 28
ID - Indonesia 27
TR - Turchia 24
JP - Giappone 23
PL - Polonia 23
BG - Bulgaria 21
MX - Messico 21
IQ - Iraq 16
ES - Italia 15
UA - Ucraina 13
ZA - Sudafrica 12
PH - Filippine 11
CO - Colombia 10
AZ - Azerbaigian 9
LT - Lituania 9
MA - Marocco 9
SA - Arabia Saudita 9
EC - Ecuador 8
PY - Paraguay 8
VE - Venezuela 8
AT - Austria 7
PK - Pakistan 7
BE - Belgio 6
CZ - Repubblica Ceca 6
PE - Perù 6
UZ - Uzbekistan 6
IE - Irlanda 5
AE - Emirati Arabi Uniti 4
BY - Bielorussia 4
EG - Egitto 4
ET - Etiopia 4
EU - Europa 4
AU - Australia 3
CH - Svizzera 3
CL - Cile 3
GR - Grecia 3
HN - Honduras 3
HR - Croazia 3
KE - Kenya 3
SV - El Salvador 3
TH - Thailandia 3
A2 - ???statistics.table.value.countryCode.A2??? 2
BO - Bolivia 2
CR - Costa Rica 2
DK - Danimarca 2
DO - Repubblica Dominicana 2
DZ - Algeria 2
GT - Guatemala 2
LB - Libano 2
LU - Lussemburgo 2
MY - Malesia 2
NP - Nepal 2
OM - Oman 2
PT - Portogallo 2
RO - Romania 2
TN - Tunisia 2
UY - Uruguay 2
AL - Albania 1
AM - Armenia 1
BA - Bosnia-Erzegovina 1
BB - Barbados 1
CI - Costa d'Avorio 1
CY - Cipro 1
DM - Dominica 1
EE - Estonia 1
GA - Gabon 1
GD - Grenada 1
HU - Ungheria 1
IL - Israele 1
JM - Giamaica 1
KG - Kirghizistan 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
NG - Nigeria 1
PA - Panama 1
PR - Porto Rico 1
PS - Palestinian Territory 1
QA - Qatar 1
TT - Trinidad e Tobago 1
TW - Taiwan 1
Totale 9.911
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Città #
Ashburn 625
Singapore 594
Fairfield 562
Chandler 501
San Jose 350
Woodbridge 239
Seattle 232
San Mateo 222
Houston 214
Cambridge 188
Ann Arbor 178
Wilmington 177
Santa Clara 165
Moscow 152
Dallas 145
Columbus 124
Princeton 113
Ho Chi Minh City 112
Hanoi 107
Los Angeles 100
Beijing 90
Helsinki 89
The Dalles 87
New York 83
Seoul 81
Riga 70
Jacksonville 69
Council Bluffs 66
Trento 62
Lauterbourg 58
Munich 51
Hong Kong 49
Orem 45
San Diego 40
Dearborn 34
Buffalo 33
Boardman 29
Da Nang 28
St Louis 27
São Paulo 27
Chicago 26
Como 26
London 26
North Bergen 24
San Paolo di Civitate 22
Sofia 20
Denver 19
Fremont 19
Haiphong 19
Hefei 19
Warsaw 19
Toronto 18
Jakarta 16
Milan 16
Rome 16
Tokyo 16
Montreal 15
Dong Ket 14
Izmir 13
Perugia 13
Salt Lake City 13
Turku 13
Bologna 12
Brooklyn 12
Chennai 12
Norwalk 12
Cavalese 11
Elk Grove Village 11
Falkenstein 11
Frankfurt am Main 11
Stockholm 11
Amsterdam 10
Atlanta 10
Lappeenranta 10
Ninh Bình 10
Shanghai 10
Tolentino 10
Biên Hòa 9
Hillsboro 9
Mexico City 9
Nanjing 9
Poplar 9
Washington 9
Baku 8
Can Tho 8
Des Moines 8
Hải Dương 8
Naples 8
Nuremberg 8
Rio de Janeiro 8
San Francisco 8
Bassano del Grappa 7
Bến Tre 7
Curitiba 7
Guangzhou 7
Johannesburg 7
Kensington 7
Amman 6
Baghdad 6
Boston 6
Totale 6.961
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Nome #
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 303
Regulation of HuR structure and function by dihydrotanshinone-I 258
Pharmacological inactivation of the prion protein by targeting a folding intermediate 249
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 247
Full atomistic model of prion structure and conversion 242
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 221
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 213
Acute Neurotoxicity Models of Prion Disease 204
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo 196
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo 190
Understanding prion structure and conversion 187
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells 181
All-Atom Simulation of HET-s Prion Replication 180
Mutant prion protein expression is associated with an alteration of the rab GDP dissociation inhibitor α (GDI)/rab11 pathway 177
Pharmacological Agents Targeting the Cellular Prion Protein 171
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis 171
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide 170
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 170
Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: A novel pharmacological strategy against brain injury 165
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention 165
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity 165
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein 161
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 160
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity 154
Ok google, how could i design therapeutics against prion diseases? 154
Common therapeutic strategies for prion and Alzheimer's diseases 151
Prion protein ligands as therapeutic agents for neurodegenerative disorders 149
The cellular prion protein beyond prion diseases 147
The N-terminal, polybasic region of PrP C dictates the efficiency of prion propagation by binding to PrP Sc 143
Enantiomers of the prion protein degrader SM875: Production and configurational assignment, in silico analysis and in vitro evaluation 142
Modeling PrPSc Generation Through Deformed Templating 141
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention 141
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity 140
Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases 139
A designer chaperone against prion diseases 139
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia 136
The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers 134
The N-terminal, polybasic region is critical for prion protein neuroprotective activity 134
Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities 132
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains 131
Non-infectious aggregates of the prion protein react with several PrP Sc-directed antibodies 127
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse 126
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells 125
Generation, optimization and characterization of novel anti-prion compounds 120
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases 120
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 117
Role of lipid rafts and GM1 in the segregation and processing of prion protein 114
Proteasome inhibition and aggregation in Parkinson's disease: A comparative study in untransfected and transfected cells 113
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein 111
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation 109
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan 103
Immunopurification of pathological prion protein aggregates 101
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice 98
A Method for Identifying Intermediates 98
Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity 98
Functional, pathogenic, and pharmacological roles of protein folding intermediates 96
Gene expression profiling in trigeminal ganglia from Cntnap2-/- and Shank3b-/- mouse models of autism spectrum disorder 95
Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans 93
Prion protein promotes copper toxicity in Wilson disease 91
Targeting the cellular prion protein to treat neurodegeneration 89
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies 87
null 86
Redox regulation of cyclophilin A by glutathionylation 86
Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion 84
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint 81
Small moleules inducing the degradation of the cellular prion protein 77
Ion channels induced by the prion protein: Mediators of neurotoxicity 73
Mapping cryptic phosphorylation sites in the human proteome 66
Small molecules inducing the degradation of the cellular prion protein 64
Infectious and pathogenic forms of PrP 63
null 62
Therapeutic Trajectories in Human Prion Diseases 61
The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens 55
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of sars-cov-2 infectivity 50
Beneficial effects of synthetic torpor in a fast-progressing mouse model of amyotrophic lateral sclerosis 34
Prion protein at the crossroads of physiology and disease 9
Totale 10.135
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Categoria #
all - tutte 43.655
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 1.352
selected - selezionate 0
volume - volumi 1.437
Totale 46.444
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022852 52 217 7 33 8 21 35 190 35 63 99 92
2022/2023990 102 129 6 138 108 150 7 69 163 21 49 48
2023/2024417 20 52 23 20 36 86 48 37 4 14 12 65
2024/20251.707 11 15 130 280 121 169 38 80 233 340 145 145
2025/20263.879 269 118 377 606 415 305 715 111 337 299 196 131
2026/202794 94 0 0 0 0 0 0 0 0 0 0 0
Totale 10.135