IRIS
Biasini, Emiliano
 Distribuzione geografica
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Continente #
NA - Nord America 4.779
AS - Asia 1.507
EU - Europa 1.274
SA - Sud America 253
AF - Africa 20
Continente sconosciuto - Info sul continente non disponibili 6
OC - Oceania 2
Totale 7.841
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Nazione #
US - Stati Uniti d'America 4.733
SG - Singapore 870
CN - Cina 343
IT - Italia 335
RU - Federazione Russa 301
BR - Brasile 204
FI - Finlandia 134
DE - Germania 114
VN - Vietnam 103
SE - Svezia 101
GB - Regno Unito 99
LV - Lettonia 70
JO - Giordania 44
NL - Olanda 36
CA - Canada 27
ID - Indonesia 25
AR - Argentina 23
BG - Bulgaria 20
TR - Turchia 20
IN - India 17
HK - Hong Kong 15
JP - Giappone 14
MX - Messico 14
BD - Bangladesh 11
UA - Ucraina 10
ZA - Sudafrica 9
IQ - Iraq 8
ES - Italia 7
PL - Polonia 7
PY - Paraguay 7
AT - Austria 6
KR - Corea 6
LT - Lituania 6
VE - Venezuela 6
AZ - Azerbaigian 5
EC - Ecuador 5
FR - Francia 5
AE - Emirati Arabi Uniti 4
CO - Colombia 4
EU - Europa 4
IE - Irlanda 4
MA - Marocco 4
UZ - Uzbekistan 4
BE - Belgio 3
BY - Bielorussia 3
CZ - Repubblica Ceca 3
GR - Grecia 3
PH - Filippine 3
PK - Pakistan 3
SA - Arabia Saudita 3
A2 - ???statistics.table.value.countryCode.A2??? 2
AU - Australia 2
BO - Bolivia 2
DO - Repubblica Dominicana 2
KE - Kenya 2
LB - Libano 2
LU - Lussemburgo 2
MY - Malesia 2
AL - Albania 1
CI - Costa d'Avorio 1
CL - Cile 1
DK - Danimarca 1
EE - Estonia 1
EG - Egitto 1
GA - Gabon 1
GD - Grenada 1
GT - Guatemala 1
HU - Ungheria 1
IL - Israele 1
LA - Repubblica Popolare Democratica del Laos 1
LC - Santa Lucia 1
NG - Nigeria 1
NP - Nepal 1
QA - Qatar 1
RO - Romania 1
TH - Thailandia 1
TN - Tunisia 1
UY - Uruguay 1
Totale 7.841
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Città #
Fairfield 562
Ashburn 539
Singapore 509
Chandler 501
Woodbridge 238
Seattle 232
San Mateo 222
Houston 210
Cambridge 188
Ann Arbor 178
Wilmington 177
Santa Clara 153
Moscow 152
Dallas 138
Columbus 123
Princeton 113
Beijing 87
Helsinki 77
Riga 70
Jacksonville 69
The Dalles 66
Los Angeles 65
New York 55
Trento 54
Munich 51
San Diego 38
Dearborn 34
Buffalo 32
Como 26
North Bergen 24
Chicago 23
Boardman 22
London 22
San Paolo di Civitate 22
Fremont 19
Hefei 19
Ho Chi Minh City 19
Sofia 19
São Paulo 17
Jakarta 16
Council Bluffs 15
Hong Kong 15
Dong Ket 14
Hanoi 14
Rome 14
Cavalese 13
Denver 13
Izmir 13
Orem 13
Perugia 13
Salt Lake City 13
Turku 13
Bologna 12
Norwalk 12
Toronto 12
Falkenstein 11
Tolentino 10
Elk Grove Village 9
Nanjing 9
Stockholm 9
Tokyo 9
Washington 9
Brooklyn 8
Nuremberg 8
Shanghai 8
Bassano del Grappa 7
Curitiba 7
Des Moines 7
Guangzhou 7
Lappeenranta 7
Mexico City 7
Milan 7
Montreal 7
Poplar 7
Rio de Janeiro 7
San Francisco 7
Amsterdam 6
Ninh Bình 6
Vienna 6
Augusta 5
Baku 5
Boston 5
Chennai 5
Costa Mesa 5
Juneau 5
Naples 5
Redondo Beach 5
Warsaw 5
Altamura 4
Ankara 4
Atlanta 4
Biên Hòa 4
Bonndorf 4
Bremen 4
Campinas 4
Dublin 4
Guarulhos 4
Ha Long 4
Jinan 4
Johannesburg 4
Totale 5.658
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Nome #
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors 258
Regulation of HuR structure and function by dihydrotanshinone-I 218
An antipsychotic drug exerts anti-prion effects by altering the localization of the cellular prion protein 210
Full atomistic model of prion structure and conversion 200
Pharmacological inactivation of the prion protein by targeting a folding intermediate 196
A cationic tetrapyrrole inhibits toxic activities of the cellular prion protein 180
A Small-Molecule Inhibitor of Prion Replication and Mutant Prion Protein Toxicity 173
An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo 168
Activation of zebrafish Src family kinases by the prion protein is an amyloid-β-sensitive signal that prevents the endocytosis and degradation of E-cadherin/β-catenin complexes in vivo 163
Understanding prion structure and conversion 155
The prion protein family member Shadoo induces spontaneous ionic currents in cultured cells 154
Acute Neurotoxicity Models of Prion Disease 152
All-Atom Simulation of HET-s Prion Replication 146
Exploring the role of MKK7 in excitotoxicity and cerebral ischemia: A novel pharmacological strategy against brain injury 145
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface 143
Mutant prion protein expression is associated with an alteration of the rab GDP dissociation inhibitor α (GDI)/rab11 pathway 137
A Drug-Based Cellular Assay (DBCA) for studying cytotoxic and cytoprotective activities of the prion protein: A practical guide 137
A novel, drug-based, cellular assay for the activity of neurotoxic mutants of the prion protein 136
Characterization of Physical, Mechanical, and Biological Properties of SilkBridge Nerve Conduit after Enzymatic Hydrolysis 135
Pharmacological Agents Targeting the Cellular Prion Protein 133
Ok google, how could i design therapeutics against prion diseases? 132
Common therapeutic strategies for prion and Alzheimer's diseases 131
Decoding the function of the N-terminal tail of the cellular prion protein to inspire novel therapeutic avenues for neurodegenerative diseases 130
An N-terminal polybasic domain and cell surface localization are required for mutant prion protein toxicity 129
Analysis of the cerebellar proteome in a transgenic mouse model of inherited prion disease reveals preclinical alteration of calcineurin activity 128
A mutant prion protein sensitizes neurons to glutamate-induced excitotoxicity 126
The N-terminal, polybasic region of PrP C dictates the efficiency of prion propagation by binding to PrP Sc 123
Enantiomers of the prion protein degrader SM875: Production and configurational assignment, in silico analysis and in vitro evaluation 120
The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers 120
The cellular prion protein beyond prion diseases 119
The hydrophobic core region governs mutant prion protein aggregation and intracellular retention 118
Modeling PrPSc Generation Through Deformed Templating 118
Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities 115
The toxicity of a mutant prion protein is cell-autonomous, and can be suppressed by wild-type prion protein on adjacent cells 111
The N-terminal, polybasic region is critical for prion protein neuroprotective activity 110
Astrocytic microdomains from mouse cortex gain molecular control over long-term information storage and memory retention 109
A designer chaperone against prion diseases 108
Defective cyclophilin A induces TDP-43 proteinopathy: implications for amyotrophic lateral sclerosis and frontotemporal dementia 107
Synthetic amyloid-β oligomers impair long-term memory independently of cellular prion protein 102
Prion protein ligands as therapeutic agents for neurodegenerative disorders 102
Proteasome inhibition and aggregation in Parkinson's disease: A comparative study in untransfected and transfected cells 99
Epitope scanning indicates structural differences in brain-derived monomeric and aggregated mutant prion proteins related to genetic prion diseases 98
The Compelling Demand for an Effective PrPC-Directed Therapy against Prion Diseases 98
Generation, optimization and characterization of novel anti-prion compounds 96
Mutant PrP is delayed in its exit from the endoplasmic reticulum, but neither wild-type nor mutant PrP undergoes retrotranslocation prior to proteasomal degradation 95
Immunopurification of pathological prion protein aggregates 92
Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency 89
Non-infectious aggregates of the prion protein react with several PrP Sc-directed antibodies 89
GFP-tagged mutant prion protein forms intra-axonal aggregates in transgenic mice 88
Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans 88
null 86
Pliability in the m6A-Binding Region Extends Druggability of YTH Domains 82
Targeting the cellular prion protein to treat neurodegeneration 78
A Method for Identifying Intermediates 78
Multiple biochemical similarities between infectious and non-infectious aggregates of a prion protein carrying an octapeptide insertion 77
Proteomic analysis of spinal cord of presymptomatic amyotrophic lateral sclerosis G93A SOD1 mouse 77
Identification of the zebrafish homologues of IMPG2, a retinal proteoglycan 74
Role of lipid rafts and GM1 in the segregation and processing of prion protein 74
Doxycycline Inhibition of a Pseudotyped Virus Transduction Does Not Translate to Inhibition of SARS-CoV-2 Infectivity 69
Ion channels induced by the prion protein: Mediators of neurotoxicity 66
Redox regulation of cyclophilin A by glutathionylation 66
Functional, pathogenic, and pharmacological roles of protein folding intermediates 64
null 62
Gene expression profiling in trigeminal ganglia from Cntnap2-/- and Shank3b-/- mouse models of autism spectrum disorder 61
Ligands binding to the prion protein induce its proteolytic release with therapeutic potential in neurodegenerative proteinopathies 61
Infectious and pathogenic forms of PrP 49
Small molecules inducing the degradation of the cellular prion protein 46
Prion protein promotes copper toxicity in Wilson disease 44
A quinolin-8-ol sub-millimolar inhibitor of UGGT, the ER glycoprotein folding quality control checkpoint 40
Small moleules inducing the degradation of the cellular prion protein 37
Doxycycline inhibition of a pseudotyped virus transduction does not translate to inhibition of sars-cov-2 infectivity 31
The evolution of eukaryotic linear motifs governing the function of androgen receptor from fish to Homo sapiens 27
All-Atom Simulation of the HET-s Prion Replication 21
Mapping cryptic phosphorylation sites in the human proteome 21
Ligands binding to the cellular prion protein induce its protective proteolytic release with therapeutic potential in neurodegenerative proteinopathies 14
Beneficial effects of synthetic torpor in a fast-progressing mouse model of amyotrophic lateral sclerosis 14
Therapeutic Trajectories in Human Prion Diseases 11
Prion protein at the crossroads of physiology and disease 9
Totale 8.068
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Categoria #
all - tutte 37.882
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 1.049
selected - selezionate 0
volume - volumi 1.198
Totale 40.129
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/2021548 0 0 0 0 0 108 51 83 50 112 98 46
2021/2022852 52 217 7 33 8 21 35 190 35 63 99 92
2022/2023990 102 129 6 138 108 150 7 69 163 21 49 48
2023/2024417 20 52 23 20 36 86 48 37 4 14 12 65
2024/20251.707 11 15 130 280 121 169 38 80 233 340 145 145
2025/20261.906 269 118 379 629 423 88 0 0 0 0 0 0
Totale 8.068