Cortical Astrocyte Progenitors and Astrocytes from Human Pluripotent Stem Cells

Astrocytes coordinate several homeostatic processes of the central nervous system and play essential roles for normal brain development and response to disease conditions. Protocols for the conversion of human induced pluripotent stem cells (hiPSCs) into mature astrocytes have opened to the generation of in vitro systems to explore astrocytes’ functions in living human cell contexts and patient-specific settings. In this study, we present an optimized monolayer procedure to commit hiPSC-deriv...

Reinforcement Learning-Based Connectivity Restoration in an Ocean Network of Fishing Vessels

An Offshore Communication Network (OCN) is a network of fishing vessels at sea aimed at providing wireless Internet access over the ocean. The connectivity of fishing vessels is essential to disseminate messages, monitor emergency management, and provide information services. The impact of extreme weather conditions on wireless signals, the inability to deploy additional infrastructure, the movements induced by sea waves, the expanded mobility freedom at sea, and the non-uniform density of ...

Fragmenta [Libri IV-VII]

Solar Models in Light of New High Metallicity Measurements from Solar Wind Data

We study the impact of new metallicity measurements, from solar wind data, on the solar model. The "solar modeling problem" refers to the persisting discrepancy between helioseismological observations and predictions of solar models computed implementing state-of-the-art photospheric abundances. We critically reassess the problem, in particular considering the new set of abundances of von Steiger & Zurbuchen, determined through the in situ collection of solar wind samples from polar coron...