08 Tesi di dottorato (Doctoral Thesis)

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08.1 Tesi di dottorato (Doctoral Thesis) 2933

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EnogisAI: An Artificial Intelligence Framework for Predictive Agronomics

Ensuring the quality and health standards necessary to feed the growing population is a critical challenge. Smart farming technologies combined with artificial intelligence (AI) represent an opportunity to improve crop quality and yield while efficiently and sustainably using the available planetary resources. This thesis describes EnogisAI: a comprehensive framework for developing and adopting agronomic AI solutions in the field. EnogisAI encompasses all the critical aspects of an AI solutio...

Modulation of BAZ2 Proteins as a Potential Therapeutic Strategy in Cancer and Neurological Disorders

The complex landscape behind protein homeostasis involves a highly sophisticated system devoted to maintaining cellular balance and preventing dysfunction. In this context, the cellular machinery acts as a quality control mechanism, rapidly identifying and eliminating proteins that could impair normal cell functioning. Currently, such a mechanism is strategically employed by researchers to promote the degradation of proteins of interest (POI), acting as relevant players in pathological condit...

The structural organization of higher-order networks: Measures, algorithms and software for hypergraphs

Traditional network models have revealed important properties of real-world systems, including small-world and clustering organization. Yet, they often face limitations in capturing the full complexity of real-world systems. Over the years, researchers have devoted a lot of attention to expanding the set of frameworks available to model complex systems, incrementally encoding more features about the interactions, such as direction, time and multiplexity. Mounting empirical evidence, from meta...

Advancements in Mass Spectrometry - Based Techniques for the Traceability and Safety of Cereal Products

Consumer preference in recent years has made a big shift towards organic products, while studies have shown that consumers are willing to pay premium prices for foods with traceability certification labels. Strict rules are set by European and international regulatory bodies for the labelling of such products. Nevertheless, new cases of food fraud continue to arise, constituting a threat for the economy and potentially for human health. The development of analytical techniques for the charact...

Rapid Startup of Aerobic Granular Sludge Using Cationic Polymer For Industrial Wastewater Treatment

The conventional activated sludge (CAS) process is used worldwide for municipal and industrial wastewater treatment. This technology has been used for over 100 years, providing sanitation and minimizing environmental damage. However, the approach is no longer deemed sustainable due to its extensive land footprint, recirculation flows, and complex process designs that demand multiple units for the removal of carbon, nitrogen, and phosphorus from wastewater. The CAS process currently faces a cr...

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