Sighel, Denise
Sighel, Denise
CIBIO (29/10/12-)
Design and synthesis of reversine-like molecules as Aurora B kinase inhibitors
2015-01-01 Sighel, Denise; Bosco, Bartolomeo; Defant, Andrea; Casarosa, Simona; Mancini, Ines
EGCG Disrupts the LIN28B/Let-7 Interaction and Reduces Neuroblastoma Aggressiveness
2024-01-01 Cocchi, Simona; Greco, Valentina; Sidarovich, Viktoryia; Vigna, Jacopo; Broso, Francesca; Corallo, Diana; Zasso, Jacopo; Re, Angela; Rosatti, Emanuele Filiberto; Longhi, Sara; Defant, Andrea; Ladu, Federico; Sanna, Vanna; Adami, Valentina; D'Agostino, Vito; Sturlese, Mattia; Sechi, Mario; Aveic, Sanja; Mancini, Ines; Sighel, Denise; Quattrone, Alessandro
Expanding the Chemical Space of Arsenicin A-C Related Polyarsenicals and Evaluation of Some Analogs as Inhibitors of Glioblastoma Stem Cell Growth
2023-01-01 Vigna, Jacopo; Sighel, Denise; Rosatti, Emanuele Filiberto; Defant, Andrea; Pancher, Michael; Sidarovich, Viktoryia; Quattrone, Alessandro; Mancini, Ines
Hybrid Molecules Containing Naphthoquinone and Quinolinedione Scaffolds as Antineoplastic Agents
2022-01-01 Mancini, Ines; Vigna, Jacopo; Sighel, Denise; Defant, Andrea
Inhibition of mitochondrial translation as a novel strategy to eradicate glioblastoma stem cells
2018-01-01 Sighel, Denise
Inhibition of mitochondrial translation suppresses glioblastoma stem cell growth
2021-01-01 Sighel, D.; Notarangelo, M.; Aibara, S.; Re, A.; Ricci, G.; Guida, M.; Soldano, A.; Adami, V.; Ambrosini, C.; Broso, F.; Rosatti, E. F.; Longhi, S.; Buccarelli, M.; D'Alessandris, Q. G.; Giannetti, S.; Pacioni, S.; Ricci-Vitiani, L.; Rorbach, J.; Pallini, R.; Roulland, S.; Amunts, A.; Mancini, I.; Modelska, A.; Quattrone, A.
Microwave-assisted synthesis of new imide-and formamide-derivatives of 2(3H)-benzoxazolinones and 2(3H)-benzothiazolinones
2017-01-01 Seddiki, Khemissi; Yahia, Wassila; Liacha, Messaoud; Defant, Andrea; Sighel, Denise; Mancini, Ines
Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery
2019-01-01 D’Agostino, Vito Giuseppe; Sighel, Denise; Zucal, Chiara; Bonomo, Isabelle; Micaelli, Mariachiara; Lolli, Graziano; Provenzani, Alessandro; Quattrone, Alessandro; Adami, Valentina
Small-Molecule Ebselen Binds to YTHDF Proteins Interfering with the Recognition of N 6-Methyladenosine-Modified RNAs
2022-01-01 Micaelli, Mariachiara; Dalle Vedove, Andrea; Cerofolini, Linda; Vigna, Jacopo; Sighel, Denise; Zaccara, Sara; Bonomo, Isabelle; Poulentzas, Georgios; Rosatti, Emanuele Filiberto; Cazzanelli, Giulia; Alunno, Laura; Belli, Romina; Peroni, Daniele; Dassi, Erik; Murakami, Shino; Jaffrey, Samie R; Fragai, Marco; Mancini, Ines; Lolli, Graziano; Quattrone, Alessandro; Provenzani, Alessandro
Streptogramin A derivatives as mitochondrial translation inhibitors to suppress glioblastoma stem cell growth
2023-01-01 Sighel, Denise; Battistini, Giulia; Rosatti, Emanuele Filiberto; Vigna, Jacopo; Pavan, Matteo; Belli, Romina; Peroni, Daniele; Alessandrini, Federica; Longhi, Sara; Pancher, Michael; Rorbach, Joanna; Moro, Stefano; Quattrone, Alessandro; Mancini, Ines
Synthesis of 2,6-diamino-substituted purine derivatives and evaluation of cell cycle arrest in breast and colorectal cancer cells
2018-01-01 Bosco, Bartolomeo; Defant, Andrea; Messina, Andrea; Incitti, Tania; Sighel, Denise; Bozza, Angela; Ciribilli, Yari; Inga, Alberto; Casarosa, Simona; Mancini, Ines