Zucal, Chiara
Zucal, Chiara
CIBIO (29/10/12-)
APO866 Increases Antitumor Activity of Cyclosporin-A by Inducing Mitochondrial and Endoplasmic Reticulum Stress in Leukemia Cells
2015-01-01 Cagnetta, Antonia; Caffa, Irene; Acharya, Chirag; Soncini, Debora; Acharya, Prakrati; Adamia, Sophia; Pierri, Ivana; Bergamaschi, Micaela; Garuti, Anna; Fraternali, Giulio; Mastracci, Luca; Provenzani, Alessandro; Zucal, Chiara; Damonte, Gianluca; Salis, Annalisa; Montecucco, Fabrizio; Patrone, Franco; Ballestrero, Alberto; Bruzzone, Santina; Gobbi, Marco; Nencioni, Alessio; Cea, Michele
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA
2018-01-01 Thongon, Natthakan; Zucal, Chiara; D'Agostino, Vito Giuseppe; Tebaldi, Toma; Ravera, Silvia; Zamporlini, Federica; Piacente, Francesco; Moschoi, Ruxanda; Raffaelli, Nadia; Quattrone, Alessandro; Nencioni, Alessio; Peyron, Jean-Francois; Provenzani, Alessandro
Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function
2015-01-01 D'Agostino, Vito Giuseppe; Lal, Preet; Mantelli, Barbara; Tiedje, Christopher; Zucal, Chiara; Thongon, Natthakan; Gaestel, Matthias; Latorre, Elisa; Marinelli, Luciana; Seneci, Pierfausto; Amadio, Marialaura; Provenzani, Alessandro
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition
2015-01-01 Zucal, Chiara; D'Agostino, Vito Giuseppe; Casini, Antonio; Mantelli, Barbara; Thongon, Natthakan; Soncini, Debora; Caffa, Irene; Cea, Michele; Ballestrero, Alberto; Quattrone, Alessandro; Indraccolo, Stefano; Nencioni, Alessio; Provenzani, Alessandro
Exploration of ligand binding modes towards the identification of compounds targeting HuR: a combined STD-NMR and Molecular Modelling approach
2018-01-01 Vasile, Francesca; Della Volpe, Serena; Ambrosio, Francesca Alessandra; Costa, Giosuè; Unver, M. Yagiz; Zucal, Chiara; Rossi, Daniela; Martino, Emanuela; Provenzani, Alessandro; Hirsch, Anna K. H.; Alcaro, Stefano; Potenza, Donatella; Collina, Simona
Fasting-mimicking diet and hormone therapy induce breast cancer regression
2020-01-01 Caffa, I.; Spagnolo, V.; Vernieri, C.; Valdemarin, F.; Becherini, P.; Wei, M.; Brandhorst, S.; Zucal, C.; Driehuis, E.; Ferrando, L.; Piacente, F.; Tagliafico, A.; Cilli, M.; Mastracci, L.; Vellone, V. G.; Piazza, S.; Cremonini, A. L.; Gradaschi, R.; Mantero, C.; Passalacqua, M.; Ballestrero, A.; Zoppoli, G.; Cea, M.; Arrighi, A.; Odetti, P.; Monacelli, F.; Salvadori, G.; Cortellino, S.; Clevers, H.; De Braud, F.; Sukkar, S. G.; Provenzani, A.; Longo, V. D.; Nencioni, A.
Forty keratin-associated beta-proteins (beta-keratins) form the hard layers of scales, claws, and adhesive pads in the green anole lizard, Anolis carolinensis.
2010-01-01 L., Dalla Valle; A., Nardi; G., Bonazza; Zucal, Chiara; D., Emera; L., Alibardi
Identification and Characterization of an RRM-Containing, RNA Binding Protein in Acinetobacter baumannii
2022-01-01 Ciani, Caterina; Pérez-Ràfols, Anna; Bonomo, Isabelle; Micaelli, Mariachiara; Esposito, Alfonso; Zucal, Chiara; Belli, Romina; D'Agostino, Vito Giuseppe; Bianconi, Irene; Calderone, Vito; Cerofolini, Linda; Massidda, Orietta; Whalen, Michael Bernard; Fragai, Marco; Provenzani, Alessandro
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors
2018-01-01 Manzoni, Leonardo; Zucal, Chiara; Maio, Danilo Di; D'Agostino, Vito G; Thongon, Natthakan; Bonomo, Isabelle; Lal, Preet; Miceli, Marco; Baj, Vanessa; Brambilla, Marta; Cerofolini, Linda; Elezgarai, Saioa; Biasini, Emiliano; Luchinat, Claudio; Novellino, Ettore; Fragai, Marco; Marinelli, Luciana; Provenzani, Alessandro; Seneci, Pierfausto
Metodo per l'isolamento di vescicole extracellulari da materiale biologico (METHOD FOR ISOLATING EXTRACELLULAR VESICLES FROM BIOLOGICAL MATERIAL)
2017-01-01 D'Agostino, Vito Giuseppe; Provenzani, Alessandro; Quattrone, Alessandro; Notarangelo, Michela; Zucal, Chiara; Pesce, Isabella; Modelska, Angelika
Molecular Effects of the Nampt Inhibitor FK866 on Leukemia Cells
2016-01-01 Zucal, Chiara
NEW AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY
2016-01-01 Provenzani, Alessandro; D'Agostino, Vito Giuseppe; Thongon, Natthakan; Zucal, Chiara; Lal, Preet; Adami, Valentina; Seneci, Pierfausto; Manzoni, Leonardo; Marinelli, Luciana; Novellino, Ettore; Fragai, Marco; Luchinat, Claudio; Cerofolini, Linda; Fuccio, Carmelo
Novel Compounds Targeting the RNA-Binding Protein HuR. Structure-Based Design, Synthesis, and Interaction Studies
2019-01-01 Della Volpe, Serena; Nasti, Rita; Queirolo, Michele; Unver, M. Yagiz; Jumde, Varsha K.; Dömling, Alexander; Vasile, Francesca; Potenza, Donatella; Ambrosio, Francesca Alessandra; Costa, Giosué; Alcaro, Stefano; Zucal, Chiara; Provenzani, Alessandro; Di Giacomo, Marcello; Rossi, Daniela; Hirsch, Anna K. H.; Collina, Simona
Regulation of HuR structure and function by dihydrotanshinone-I
2017-01-01 Lal, Preet; Cerofolini, Linda; D'Agostino, Vito Giuseppe; Zucal, Chiara; Fuccio, Carmelo; Bonomo, Isabelle; Dassi, Erik; Giuntini, Stefano; Di maio, Danilo; Vishwakarma, Vikalp; Preet, Ranjan; Williams, Sha Neisha; Fairlamb, Max S.; Munk, Rachel; Lehrmann, Elin; Abdelmohsen, Kotb; Elezgarai, Saioa R.; Luchinat, Claudio; Novellino, Ettore; Quattrone, Alessandro; Biasini, Emiliano; Manzoni, Leonardo; Gorospe, Myriam; Dixon, Dan A.; Seneci, Pierfausto; Marinelli, Luciana; Fragai, Marco; Provenzani, Alessandro
Role of ox-PAPCs in the differentiation of mesenchymal stem cells (MSCs) and Runx2 and PPARγ2 expression in MSCs-like of osteoporotic patients.
2011-01-01 Valenti, M. T.; U., Garbin; A., Pasini; Zanatta, Marco; C., Stranieri; S., Manfro; Zucal, Chiara; L., Dalle Carbonare
Runx-2 gene expression is associated with age-related changes of bone mineral density in the healthy young-adult population.
2012-01-01 Zanatta, Marco; Valenti, M. T.; L., Donatelli; Zucal, Chiara; L., Dalle Carbonare
Screening Approaches for Targeting Ribonucleoprotein Complexes: A New Dimension for Drug Discovery
2019-01-01 D’Agostino, Vito Giuseppe; Sighel, Denise; Zucal, Chiara; Bonomo, Isabelle; Micaelli, Mariachiara; Lolli, Graziano; Provenzani, Alessandro; Quattrone, Alessandro; Adami, Valentina
Targeting the multifaceted HuR protein, benefits and caveats
2015-01-01 Zucal, Chiara; D'Agostino, Vito Giuseppe; Loffredo, Rosa; Mantelli, Barbara; Thongon, Natthakan; Lal, Preet; Latorre, Elisa; Provenzani, Alessandro
The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level
2016-01-01 Thongon, Natthakan; Castiglioni, Ilaria; Zucal, Chiara; Latorre, Elisa; D'Agostino, Vito Giuseppe; Bauer, Inga; Pancher, Michael; Ballestrero, Alberto; Feldmann, Georg; Nencioni, Alessio; Provenzani, Alessandro
The knockdown of maternal glucocorticoid receptor mRNA alters embryo development in zebrafish.
2011-01-01 Pikulkaew, S; Benato, F; Celeghin, A; Zucal, Chiara; Skobo, T; Colombo, L; Dalla Valle, L.