Reali, Federico
Reali, Federico
Ingegneria e scienza dell'Informaz (29/10/12-)
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis
2024-01-01 Reali, Federico; Fochesato, Anna; Kaddi, Chanchala; Visintainer, Roberto; Watson, Shayne; Levi, Micha; Dartois, Véronique; Azer, Karim; Marchetti, Luca
A Novel Insulin/Glucose Model after a Mixed-Meal Test in Patients with Type 1 Diabetes on Insulin Pump Therapy
2016-01-01 Marchetti, Luca; Reali, Federico; Dauriz, Marco; Brangani, Corinna; Boselli, Linda; Ceradini, Giulia; Bonora, Enzo; Bonadonna, Riccardo C; Priami, Corrado
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat
2020-01-01 Abrams, Ruth; Kaddi, Chanchala D.; Tao, Mengdi; Leiser, Randolph J.; Simoni, Giulia; Reali, Federico; Tolsma, John; Jasper, Paul; Rijn, Zachary; Li, Jing; Niesner, Bradley; Barrett, Jeffrey S.; Marchetti, Luca; Peterschmitt, M. Judith; Azer, Karim; Neves‐zaph, Susana
A retrospective analysis of the COVID-19 pandemic evolution in Italy
2021-01-01 Fochesato, Anna; Simoni, Giulia; Reali, Federico; Giordano, Giulia; Domenici, Enrico; Marchetti, Luca
A robust computational pipeline for model-based and data-driven phenotype clustering
2020-01-01 Simoni, Giulia; Kaddi, Chanchala; Tao, Mengdi; Reali, Federico; Tomasoni, Danilo; Priami, Corrado; Azer, Karim; Neves-Zaph, Susana; Marchetti, Luca
Digital Twins and Virtual Populations: Applications in Quantitative Systems Pharmacology
2023-01-01 Reali, Federico; Paris, Alessio; Giampiccolo, Stefano; Righetti, Elena; Marchetti, Luca
Dynamical models for diabetes: insights into insulin resistance and type 1 diabetes
2017-01-01 Reali, Federico
Incorporating extrinsic noise into the stochastic simulation of biochemical reactions: A comparison of approaches
2018-01-01 Vo Hong, Thanh; Marchetti, Luca; Reali, Federico; Priami, Corrado
Integrated quantitative systems pharmacology (QSP) model of lysosomal diseases provides an innovative computational platform to support research and therapeutic development for the sphingolipidoses
2018-01-01 Kaddi, Chanchala; Reali, Federico; Marchetti, Luca; Niesner, Bradley; Parolo, Silvia; Simoni, Giulia; Zaph, Susana; Tao, Mengdi; Abrams, Ruth; van Rijn, Zachary; Leonard, John; Judith Peterschmitt, M.; Puga, Ana Cristina; Mange, Kevin; Barrett, Jeffrey S.; Priami, Corrado; Schuchman, Edward H.; Azer, Karim
Mechanistic interplay between ceramide and insulin resistance
2017-01-01 Reali, F.; Morine, M. J.; Kahramanogullari, O.; Raichur, S.; Schneider, H. C.; Crowther, D.; Priami, C.
Mechanistic models of alpha-synuclein homeostasis for Parkinson's disease: A blueprint for therapeutic intervention
2022-01-01 Righetti, Elena; Antonello, Alice; Marchetti, Luca; Domenici, Enrico; Reali, Federico
Optimization Algorithms for Computational Systems Biology
2017-01-01 Reali, Federico; Priami, Corrado; Marchetti, Luca
QSPcc reduces bottlenecks in computational model simulations
2021-01-01 Tomasoni, D.; Paris, A.; Giampiccolo, S.; Reali, F.; Simoni, G.; Marchetti, L.; Kaddi, C.; Neves-Zaph, S.; Priami, C.; Azer, K.; Lombardo, R.
Stochastic simulation algorithms for computational systems biology: Exact, approximate, and hybrid methods
2019-01-01 Simoni, G.; Reali, F.; Priami, C.; Marchetti, L.
Use of quantitative systems pharmacology pipelines to bridge in vitro and in vivo results in drug discovery
2023-01-01 Reali, Federico; Csikász-Nagy, Attila; Selvaggio, Gianluca