Marchetti, Luca
Marchetti, Luca
CIBIO (29/10/12-)
A closed-loop multi-level model of glucose homeostasis
2018-01-01 Uluseker, Cansu; Simoni, Giulia; Marchetti, Luca; Dauriz, Marco; Matone, Alice; Priami, Corrado
A comparison of deterministic and stochastic approaches for sensitivity analysis in computational systems biology
2020-01-01 Simoni, G.; Vo, H. T.; Priami, C.; Marchetti, L.
A hybrid stochastic model of folate-mediated one-carbon metabolism: Effect of the common C677T MTHFR variant on de novo thymidylate biosynthesis
2017-01-01 Misselbeck, Karla; Marchetti, Luca; Field, Martha S; Scotti, Marco; Priami, Corrado; Stover, Patrick J.
A Methodology Based on MP Theory for Gene Expression Analysis
2012-01-01 Marchetti, Luca; Manca, Vincenzo
A minimal PBPK model to accelerate preclinical development of drugs against tuberculosis
2024-01-01 Reali, Federico; Fochesato, Anna; Kaddi, Chanchala; Visintainer, Roberto; Watson, Shayne; Levi, Micha; Dartois, Véronique; Azer, Karim; Marchetti, Luca
A model-based framework to identify optimal administration protocols for immunotherapies in castration-resistance prostate cancer
2022-01-01 Coletti, R.; Pugliese, A.; Lunardi, A.; Caffo, O.; Marchetti, L.
A Novel Hybrid Logic-ODE Modeling Approach to Overcome Knowledge Gaps
2021-01-01 Selvaggio, G.; Cristellon, S.; Marchetti, L.
A Novel Insulin/Glucose Model after a Mixed-Meal Test in Patients with Type 1 Diabetes on Insulin Pump Therapy
2016-01-01 Marchetti, Luca; Reali, Federico; Dauriz, Marco; Brangani, Corinna; Boselli, Linda; Ceradini, Giulia; Bonora, Enzo; Bonadonna, Riccardo C; Priami, Corrado
A novel logical model of COVID-19 intracellular infection to support therapies development
2022-01-01 Piretto, E.; Selvaggio, G.; Bragantini, D.; Domenici, E.; Marchetti, L.
A parsimonious model of a mixed-meal test in patients with type 1 diabetes in insulin pump therapy
2015-01-01 Brangani, Corinna; Dauriz, Marco; Boselli, Maria Linda; Reali, Federico; Marchetti, Luca; Ceradini, Giulia; Rubbo, Ilaria; Trombetta, Maddalena; Priami, Corrado; Bonadonna, Riccardo C.
A pediatric quantitative systems pharmacology model of neurofilament trafficking in spinal muscular atrophy treated with the antisense oligonucleotide nusinersen
2023-01-01 Paris, A.; Bora, P.; Parolo, S.; Maccannell, D.; Monine, M.; van der Munnik, N.; Tong, X.; Eraly, S.; Berger, Z.; Graham, D.; Ferguson, T.; Domenici, E.; Nestorov, I.; Marchetti, L.
A QSP model of prostate cancer immunotherapy to identify effective combination therapies
2020-01-01 Coletti, Roberta; Leonardelli, Lorena; Parolo, Silvia; Marchetti, Luca
A quantitative systems pharmacology approach to support mRNA vaccine development and optimization
2021-01-01 Selvaggio, G.; Leonardelli, L.; Lofano, G.; Fresnay, S.; Parolo, S.; Medini, D.; Siena, E.; Marchetti, L.
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat
2020-01-01 Abrams, Ruth; Kaddi, Chanchala D.; Tao, Mengdi; Leiser, Randolph J.; Simoni, Giulia; Reali, Federico; Tolsma, John; Jasper, Paul; Rijn, Zachary; Li, Jing; Niesner, Bradley; Barrett, Jeffrey S.; Marchetti, Luca; Peterschmitt, M. Judith; Azer, Karim; Neves‐zaph, Susana
A retrospective analysis of the COVID-19 pandemic evolution in Italy
2021-01-01 Fochesato, Anna; Simoni, Giulia; Reali, Federico; Giordano, Giulia; Domenici, Enrico; Marchetti, Luca
A robust computational pipeline for model-based and data-driven phenotype clustering
2020-01-01 Simoni, Giulia; Kaddi, Chanchala; Tao, Mengdi; Reali, Federico; Tomasoni, Danilo; Priami, Corrado; Azer, Karim; Neves-Zaph, Susana; Marchetti, Luca
An age-dependent mathematical model of neurofilament trafficking in healthy conditions
2022-01-01 Paris, A.; Bora, P.; Parolo, S.; Monine, M.; Tong, X.; Eraly, S.; Masson, E.; Ferguson, T.; Mccampbell, A.; Graham, D.; Domenici, E.; Nestorov, I.; Marchetti, L.
An algebraic formulation of inverse problems in MP dynamics
2013-01-01 Manca, Vincenzo; Marchetti, Luca
APPLICATION OF THE MP THEORY TO SYSTEMS BIOLOGY
2012-01-01 Manca, V.; Marchetti, L.
Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy
2018-01-01 Parolo, Silvia; Marchetti, Luca; Lauria, Mario; Misselbeck, Karla Margret Eva; Scott-Boyer, Marie-Pier; Caberlotto, Laura; Priami, Corrado