Although the exact pathophysiology of MS has not been identified, mitochondrial stress can be one of the culprits in MS development. Herein, we have applied microarray analysis, single-cell sequencing analysis, and ex vivo study to elucidate the role of mitochondrial stress in PBMCs of MS patients.

The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters / Derakhshani, Afshin; Safarpour, Hossein; Abdoli Shadbad, Mahdi; Hemmat, Nima; Leone, Patrizia; Asadzadeh, Zahra; Pashazadeh, Mehrdad; Baradaran, Behzad; Racanelli, Vito. - In: FRONTIERS IN IMMUNOLOGY. - ISSN 1664-3224. - 12:(2021), pp. 70917301-70917313. [10.3389/fimmu.2021.709173]

The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters

Racanelli, Vito
2021-01-01

Abstract

Although the exact pathophysiology of MS has not been identified, mitochondrial stress can be one of the culprits in MS development. Herein, we have applied microarray analysis, single-cell sequencing analysis, and ex vivo study to elucidate the role of mitochondrial stress in PBMCs of MS patients.
2021
Derakhshani, Afshin; Safarpour, Hossein; Abdoli Shadbad, Mahdi; Hemmat, Nima; Leone, Patrizia; Asadzadeh, Zahra; Pashazadeh, Mehrdad; Baradaran, Behzad; Racanelli, Vito
The Role of Hemoglobin Subunit Delta in the Immunopathy of Multiple Sclerosis: Mitochondria Matters / Derakhshani, Afshin; Safarpour, Hossein; Abdoli Shadbad, Mahdi; Hemmat, Nima; Leone, Patrizia; Asadzadeh, Zahra; Pashazadeh, Mehrdad; Baradaran, Behzad; Racanelli, Vito. - In: FRONTIERS IN IMMUNOLOGY. - ISSN 1664-3224. - 12:(2021), pp. 70917301-70917313. [10.3389/fimmu.2021.709173]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/386872
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