Although the introduction of bortezomib as a therapeutic strategy has improved the overall survival of multiple myeloma (MM) patients, 15-20% of high-risk patients do not respond to bortezomib over time or become resistant to treatment. Therefore, the development of new therapeutic strategies, such as combination therapies, is urgently needed.

Bortezomib Treatment Modulates Autophagy in Multiple Myeloma / Di Lernia, Giuseppe; Leone, Patrizia; Solimando, Antonio Giovanni; Buonavoglia, Alessio; Saltarella, Ilaria; Ria, Roberto; Ditonno, Paolo; Silvestris, Nicola; Crudele, Lucilla; Vacca, Angelo; Racanelli, Vito. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 9:2(2020), pp. 55201-55214. [10.3390/jcm9020552]

Bortezomib Treatment Modulates Autophagy in Multiple Myeloma

Racanelli, Vito
2020-01-01

Abstract

Although the introduction of bortezomib as a therapeutic strategy has improved the overall survival of multiple myeloma (MM) patients, 15-20% of high-risk patients do not respond to bortezomib over time or become resistant to treatment. Therefore, the development of new therapeutic strategies, such as combination therapies, is urgently needed.
2020
2
Di Lernia, Giuseppe; Leone, Patrizia; Solimando, Antonio Giovanni; Buonavoglia, Alessio; Saltarella, Ilaria; Ria, Roberto; Ditonno, Paolo; Silvestris,...espandi
Bortezomib Treatment Modulates Autophagy in Multiple Myeloma / Di Lernia, Giuseppe; Leone, Patrizia; Solimando, Antonio Giovanni; Buonavoglia, Alessio; Saltarella, Ilaria; Ria, Roberto; Ditonno, Paolo; Silvestris, Nicola; Crudele, Lucilla; Vacca, Angelo; Racanelli, Vito. - In: JOURNAL OF CLINICAL MEDICINE. - ISSN 2077-0383. - 9:2(2020), pp. 55201-55214. [10.3390/jcm9020552]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/386870
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