Maule, Giulia
Maule, Giulia
CIBIO (29/10/12-)
A highly specific SpCas9 variant is identified by in vivo screening in yeast
2018-01-01 Casini, Antonio; Olivieri, Michele; Petris, Gianluca; Montagna, Claudia; Reginato, Giordano; Maule, Giulia; Lorenzin, Francesca; Prandi, Davide; Romanel, Alessandro; Demichelis, Francesca; Inga, Alberto; Cereseto, Anna
Allele specific repair of splicing mutations in cystic fibrosis through AsCas12a genome editing
2019-01-01 Maule, G.; Casini, A.; Montagna, C.; Ramalho, A. S.; De Boeck, K.; Debyser, Z.; Carlon, M. S.; Petris, G.; Cereseto, A.
Base-editing-mediated dissection of a γ-globin cis-regulatory element for the therapeutic reactivation of fetal hemoglobin expression
2022-01-01 Antoniou, P.; Hardouin, G.; Martinucci, P.; Frati, G.; Felix, T.; Chalumeau, A.; Fontana, L.; Martin, J.; Masson, C.; Brusson, M.; Maule, G.; Rosello, M.; Giovannangeli, C.; Abramowski, V.; de Villartay, J. -P.; Concordet, J. -P.; Del Bene, F.; El Nemer, W.; Amendola, M.; Cavazzana, M.; Cereseto, A.; Romano, O.; Miccio, A.
CoCas9 is a compact nuclease from the human microbiome for efficient and precise genome editing
2024-01-01 Pedrazzoli, E.; Demozzi, M.; Visentin, E.; Ciciani, M.; Bonuzzi, I.; Pezze, L.; Lucchetta, L.; Maule, G.; Amistadi, S.; Esposito, F.; Lupo, M.; Miccio, A.; Auricchio, A.; Casini, A.; Segata, N.; Cereseto, A.
Combination of lentiviral and genome editing technologies for the treatment of sickle cell disease
2022-01-01 Ramadier, S.; Chalumeau, A.; Felix, T.; Othman, N.; Aknoun, S.; Casini, A.; Maule, G.; Masson, C.; De Cian, A.; Frati, G.; Brusson, M.; Concordet, J. -P.; Cavazzana, M.; Cereseto, A.; El Nemer, W.; Amendola, M.; Wattellier, B.; Meneghini, V.; Miccio, A.
Correction of β-thalassemia by CRISPR/Cas9 editing of the α-globin locus in human hematopoietic stem cells
2021-01-01 Pavani, Giulia; Laurent, Marine; Amor, Fatima; Cantelli, Erika; Chalumeau, Anne; Maule, Giulia; Tachtsis, Alexandra; Concordet, Jean-Paul; Cereseto, Anna; Mavilio, Fulvio; Ferrari, Giuliana; Amendola, Mario
Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing
2025-01-01 Carrozzo, Irene; Maule, Giulia; Gentile, Carmelo; Umbach, Alessandro; Ciciani, Matteo; Guidone, Daniela; De Santis, Martina; Petris, Gianluca; Vicente Galietta, Luis Juan; Arosio, Daniele; Cereseto, Anna
Functional restoration of a CFTR splicing mutation through RNA delivery of CRISPR adenine base editor
2023-01-01 Amistadi, S.; Maule, G.; Ciciani, M.; Ensinck, M. M.; De Keersmaecker, L.; Ramalho, A. S.; Guidone, D.; Buccirossi, M.; Galietta, L. J. V.; Carlon, M. S.; Cereseto, A.
Gene therapy for cystic fibrosis: Progress and challenges of genome editing
2020-01-01 Maule, G.; Arosio, D.; Cereseto, A.
Generation of corrected hiPSC clones from a Cornelia de Lange Syndrome (CdLS) patient through CRISPR-Cas-based technology
2022-01-01 Umbach, Alessandro; Maule, Giulia; Kheir, Eyemen; Cutarelli, Alessandro; Foglia, Marika; Guarrera, Luca; Fava, Luca; Conti, Luciano; Garattini, Enrico; Terao, Mineko; Cereseto, Anna
Harnessing CRISPR technology for the treatment of cystic fibrosis
2020-07-06 Maule, Giulia
Prime editing functionally corrects cystic fibrosis-causing CFTR mutations in human organoids and airway epithelial cells
2024-01-01 Bulcaen, M.; Kortleven, P.; Liu, R. B.; Maule, G.; Dreano, E.; Kelly, M.; Ensinck, M. M.; Thierie, S.; Smits, M.; Ciciani, M.; Hatton, A.; Chevalier, B.; Ramalho, A. S.; Casadevall i Solvas, X.; Debyser, Z.; Vermeulen, F.; Gijsbers, R.; Sermet-Gaudelus, I.; Cereseto, A.; Carlon, M. S.
VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9
2018-01-01 Montagna, C.; Petris, G.; Casini, A.; Maule, G.; Franceschini, G. M.; Zanella, I.; Conti, L.; Arnoldi, F.; Burrone, O. R.; Zentilin, L.; Zacchigna, S.; Giacca, M.; Cereseto, A.