Lolli, Graziano
Lolli, Graziano
CIBIO (29/10/12-)
A novel class of selective CK2 inhibitors targeting its open hinge conformation
2020-01-01 Dalle Vedove, A.; Zonta, F.; Zanforlin, E.; Demitri, N.; Ribaudo, G.; Cazzanelli, G.; Ongaro, A.; Sarno, S.; Zagotto, G.; Battistutta, R.; Ruzzene, M.; Lolli, G.
Active Form of the Protein Kinase CK2 alpha(2)beta(2) holoenzyme Is a Strong Complex with Symmetric Architecture
2014-01-01 Lolli, Graziano; Ranchio, Alessandro; Battistutta, Roberto
An inhibitor's-eye view of the ATP-binding site of CDKs in different regulatory states
2014-01-01 A., Echalier; A. J., Hole; Lolli, Graziano; J. A., Endicott; M. E., Noble
Auto-inhibitory assembly of protein kinase CK2 revealed by X-ray crystallography.
2012-01-01 Lolli, Graziano; Pinna, Lorenzo; Battistutta, Roberto
Binding to DNA of the RNA-polymerase II C-Terminal Domain allows discrimination between Cdk7 ad Cdk9 phosphorylation
2009-01-01 Lolli, Graziano
Biochemical and cellular mechanism of protein kinase CK2 inhibition by deceptive curcumin
2020-01-01 Cozza, G.; Zonta, F.; Dalle Vedove, A.; Venerando, A.; Dall'Acqua, S.; Battistutta, R.; Ruzzene, M.; Lolli, G.
CAK—Cyclin-Dependent Activating Kinase: A Key Kinase in Cell Cycle Control and a Target for Drugs?
2005-01-01 Lolli, Graziano; Louise N., Johnson
Cell-permeable dual inhibitors of protein kinases CK2 and PIM-1: Structural features and pharmacological potential
2014-01-01 Cozza, Giorgio; Girardi, Cristina; Ranchio, Alessandro; Lolli, Graziano; Sarno, Stefania; Orzeszko, Andrzej; Kazimierczuk, Zygmunt; Battistutta, Roberto; Ruzzene, Maria; Pinna, Lorenzo A.
Characterization of the oligomeric states of the CK2 α2β2 holoenzyme in solution
2017-01-01 Lolli, Graziano; Naressi, Denise; Sarno, Stefania; Battistutta, Roberto
Derivatives of 3-Amino-2-methylpyridine as BAZ2B Bromodomain Ligands: In Silico Discovery and in Crystallo Validation
2016-01-01 Marchand, Jean Rémy; Lolli, Graziano; Caflisch, Amedeo
Different orientations of low-molecular-weight fragments in the binding pocket of a BRD4 bromodomain
2013-01-01 Lolli, Graziano; Battistutta, Roberto
Discovery of BAZ2A bromodomain ligands
2017-01-01 Spiliotopoulos, Dimitrios; Wamhoff, Eike-christian; Lolli, Graziano; Rademacher, Christoph; Caflisch, Amedeo
Discovery of Inhibitors of Four Bromodomains by Fragment-Anchored Ligand Docking
2017-01-01 Marchand, Jean-Rémy; Dalle Vedove, Andrea; Lolli, Graziano; Caflisch, Amedeo
Flavopiridol binding to P-TEFb (CDK9/cyclin T1)
2008-01-01 Johnson, Louise N.; Baumli, Sonja; Lolli, Graziano; Lowe, Ed
GroEL from the psychrophilic bacterium Pseudoalteromonas haloplanktis TAC 125: molecular characterization and gene cloning
2003-01-01 Alessandra, Tosco; Leila, Birolo; Stefania, Madonna; Lolli, Graziano; Giovanni, Sannia; Gennaro, Marino
High-Throughput Fragment Docking into the BAZ2B Bromodomain: Efficient in Silico Screening for X-Ray Crystallography
2016-01-01 Lolli, Graziano; Caflisch, Amedeo
Identification of a BAZ2A Bromodomain Hit Compound by Fragment Joining
2021-01-01 Dalle Vedove, Andrea; Cazzanelli, Giulia; Corsi, Jessica; Sedykh, Maria; D’Agostino, Vito Giuseppe; Caflisch, Amedeo; Lolli, Graziano
Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing
2022-01-01 Dalle Vedove, Andrea; Cazzanelli, Giulia; Batiste, Laurent; Marchand, Jean-Rémy; Spiliotopoulos, Dimitrios; Corsi, Jessica; D'Agostino, Vito Giuseppe; Caflisch, Amedeo; Lolli, Graziano
Identification of compounds inhibiting prion replication and toxicity by removing PrPC from the cell surface
2020-01-01 Biggi, S.; Pancher, M.; Stincardini, C.; Luotti, S.; Massignan, T.; Dalle Vedove, A.; Astolfi, A.; Gatto, P.; Lolli, G.; Barreca, M. L.; Bonetto, V.; Adami, V.; Biasini, E.
Inhibition of Protein Kinase CK2 by Flavonoids and Tyrphostins. A Structural Insight
2012-01-01 Lolli, Graziano; Cozza, Giorgio; Mazzorana, Marco; Tibaldi, Elena; Cesaro, Luca; Donella, Arianna; Meggio, Flavio; Venerando, Andrea; Franchin, Cinzia; Sarno, Stefania; Battistutta, Roberto; Pinna, Lorenzo