Tripathy, Debasmita
Tripathy, Debasmita
Designing Dual Transglutaminase 2/Histone Deacetylase Inhibitors Effective at Halting Neuronal Death
2018-01-01 Basso, Manuela; Chen, Huan Huan; Tripathy, Debasmita; Conte, Mariarosaria; Apperley, Kim Y. P.; De Simone, Angela; Keillor, Jeffrey W.; Ratan, Rajiv; Nebbioso, Angela; Sarno, Federica; Altucci, Lucia; Milelli, Andrea
Huntingtin-mediated axonal transport requires arginine methylation by PRMT6
2021-01-01 Migazzi, A.; Scaramuzzino, C.; Anderson, E. N.; Tripathy, D.; Hernandez, I. H.; Grant, R. A.; Roccuzzo, M.; Tosatto, L.; Virlogeux, A.; Zuccato, C.; Caricasole, A.; Ratovitski, T.; Ross, C. A.; Pandey, U. B.; Lucas, J. J.; Saudou, F.; Pennuto, M.; Basso, M.
Increased transcription of transglutaminase 1 mediates neuronal death in in vitro models of neuronal stress and Aβ1–42-mediated toxicity
2020-01-01 Tripathy, D.; Migazzi, A.; Costa, F.; Roncador, A.; Gatto, P.; Fusco, F.; Boeri, L.; Albani, D.; Juarez-Hernandez, J. L.; Musio, C.; Colombo, L.; Salmona, M.; Wilhelmus, M. M. M.; Drukarch, B.; Pennuto, M.; Basso, M.
LSD1/PRMT6-targeting gene therapy to attenuate androgen receptor toxic gain-of-function ameliorates spinobulbar muscular atrophy phenotypes in flies and mice
2023-01-01 Prakasam, Ramachandran; Bonadiman, Angela; Andreotti, Roberta; Zuccaro, Emanuela; Dalfovo, Davide; Marchioretti, Caterina; Tripathy, Debasmita; Petris, Gianluca; Anderson, Eric N.; Migazzi, Alice; Tosatto, Laura; Cereseto, Anna; Battaglioli, Elena; Sorarù, Gianni; Lim, Wooi Fang; Rinaldi, Carlo; Sambataro, Fabio; Pourshafie, Naemeh; Grunseich, Christopher; Romanel, Alessandro; Pandey, Udai Bhan; Contestabile, Andrea; Ronzitti, Giuseppe; Basso, Manuela; Pennuto, Maria
Mutations in TGM6 induce the unfolded protein response in SCA35
2017-01-01 Tripathy, Debasmita; Vignoli, Beatrice; Ramesh, Nandini; Polanco, Maria Jose; Coutelier, Marie; Stephen, Christopher D.; Canossa, Marco; Monin, Marie lorraine; Aeschlimann, Pascale; Turberville, Shannon; Aeschlimann, Daniel; Schmahmann, Jeremy D.; Hadjivassiliou, Marios; Durr, Alexandra; Pandey, Udai B.; Pennuto, Maria; Basso, Manuela
Spinocerebellar ataxia 38: structure-function analysis shows ELOVL5 G230V is proteotoxic, conformationally altered and a mutational hotspot
2023-01-01 Ferrero, Enza; Di Gregorio, Eleonora; Ferrero, Marta; Ortolan, Erika; Moon, Young-Ah; Di Campli, Antonella; Pavinato, Lisa; Mancini, Cecilia; Tripathy, Debasmita; Manes, Marta; Hoxha, Eriola; Costanzi, Chiara; Pozzi, Elisa; Rossi Sebastiano, Matteo; Mitro, Nico; Tempia, Filippo; Caruso, Donatella; Borroni, Barbara; Basso, Manuela; Sallese, Michele; Brusco, Alfredo