Thongon, Natthakan
Thongon, Natthakan
Autophagy Stimulus Promotes Early HuR Protein Activation and p62/SQSTM1 Protein Synthesis in ARPE-19 Cells by Triggering Erk1/2, p38MAPK, and JNK Kinase Pathways
2018-01-01 Marchesi, Nicoletta; Thongon, Natthakan; Pascale, Alessia; Provenzani, Alessandro; Koskela, Ali; Korhonen, Eveliina; Smedowski, Adrian; Govoni, Stefano; Kauppinen, Anu; Kaarniranta, Kai; Amadio, Marialaura
Cancer cell metabolic plasticity allows resistance to NAMPT inhibition but invariably induces dependence on LDHA
2018-01-01 Thongon, Natthakan; Zucal, Chiara; D'Agostino, Vito Giuseppe; Tebaldi, Toma; Ravera, Silvia; Zamporlini, Federica; Piacente, Francesco; Moschoi, Ruxanda; Raffaelli, Nadia; Quattrone, Alessandro; Nencioni, Alessio; Peyron, Jean-Francois; Provenzani, Alessandro
Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function
2015-01-01 D'Agostino, Vito Giuseppe; Lal, Preet; Mantelli, Barbara; Tiedje, Christopher; Zucal, Chiara; Thongon, Natthakan; Gaestel, Matthias; Latorre, Elisa; Marinelli, Luciana; Seneci, Pierfausto; Amadio, Marialaura; Provenzani, Alessandro
EIF2A-dependent translational arrest protects leukemia cells from the energetic stress induced by NAMPT inhibition
2015-01-01 Zucal, Chiara; D'Agostino, Vito Giuseppe; Casini, Antonio; Mantelli, Barbara; Thongon, Natthakan; Soncini, Debora; Caffa, Irene; Cea, Michele; Ballestrero, Alberto; Quattrone, Alessandro; Indraccolo, Stefano; Nencioni, Alessio; Provenzani, Alessandro
Interfering with HuR-RNA Interaction: Design, Synthesis and Biological Characterization of Tanshinone Mimics as Novel, Effective HuR Inhibitors
2018-01-01 Manzoni, Leonardo; Zucal, Chiara; Maio, Danilo Di; D'Agostino, Vito G; Thongon, Natthakan; Bonomo, Isabelle; Lal, Preet; Miceli, Marco; Baj, Vanessa; Brambilla, Marta; Cerofolini, Linda; Elezgarai, Saioa; Biasini, Emiliano; Luchinat, Claudio; Novellino, Ettore; Fragai, Marco; Marinelli, Luciana; Provenzani, Alessandro; Seneci, Pierfausto
Mitochondrial rewiring drives metabolic adaptation to NAD(H) shortage in triple negative breast cancer cells
2023-01-01 Carreira, Agata; Ravera, Silvia; Zucal, Chiara; Thongon, Natthakan; Caffa, Irene; Astigiano, Cecilia; Bertola, Nadia; Buongiorno, Arianna; Roccuzzo, Michela; Bisio, Alessandra; Pardini, Barbara; Nencioni, Alessio; Bruzzone, Santina; Provenzani, Alessandro
Molecular Mechanisms and Insights into the Nampt Inhibitor (FK866) Resistance in Cancers
2017-01-01 Thongon, Natthakan
NEW AZA-TANSHINONE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR USE IN THERAPY
2016-01-01 Provenzani, Alessandro; D'Agostino, Vito Giuseppe; Thongon, Natthakan; Zucal, Chiara; Lal, Preet; Adami, Valentina; Seneci, Pierfausto; Manzoni, Leonardo; Marinelli, Luciana; Novellino, Ettore; Fragai, Marco; Luchinat, Claudio; Cerofolini, Linda; Fuccio, Carmelo
Targeting the multifaceted HuR protein, benefits and caveats
2015-01-01 Zucal, Chiara; D'Agostino, Vito Giuseppe; Loffredo, Rosa; Mantelli, Barbara; Thongon, Natthakan; Lal, Preet; Latorre, Elisa; Provenzani, Alessandro
The GSK3β inhibitor BIS I reverts YAP-dependent EMT signature in PDAC cell lines by decreasing SMADs expression level
2016-01-01 Thongon, Natthakan; Castiglioni, Ilaria; Zucal, Chiara; Latorre, Elisa; D'Agostino, Vito Giuseppe; Bauer, Inga; Pancher, Michael; Ballestrero, Alberto; Feldmann, Georg; Nencioni, Alessio; Provenzani, Alessandro