Sfoglia per Autore
A comparison of deterministic and stochastic approaches for sensitivity analysis in computational systems biology
2020-01-01 Simoni, G.; Vo, H. T.; Priami, C.; Marchetti, L.
A Quantitative Systems Pharmacology Model of Gaucher Disease Type 1 Provides Mechanistic Insight Into the Response to Substrate Reduction Therapy With Eliglustat
2020-01-01 Abrams, Ruth; Kaddi, Chanchala D.; Tao, Mengdi; Leiser, Randolph J.; Simoni, Giulia; Reali, Federico; Tolsma, John; Jasper, Paul; Rijn, Zachary; Li, Jing; Niesner, Bradley; Barrett, Jeffrey S.; Marchetti, Luca; Peterschmitt, M. Judith; Azer, Karim; Neves‐zaph, Susana
A robust computational pipeline for model-based and data-driven phenotype clustering
2020-01-01 Simoni, Giulia; Kaddi, Chanchala; Tao, Mengdi; Reali, Federico; Tomasoni, Danilo; Priami, Corrado; Azer, Karim; Neves-Zaph, Susana; Marchetti, Luca
Gene expression signature of antidepressant treatment response/non-response in Flinders Sensitive Line rats subjected to maternal separation
2020-01-01 Marchetti, Luca; Lauria, M.; Caberlotto, L.; Musazzi, L.; Popoli, M.; Mathe, A. A.; Domenici, E.; Carboni, L.
A QSP model of prostate cancer immunotherapy to identify effective combination therapies
2020-01-01 Coletti, Roberta; Leonardelli, Lorena; Parolo, Silvia; Marchetti, Luca
A retrospective analysis of the COVID-19 pandemic evolution in Italy
2021-01-01 Fochesato, Anna; Simoni, Giulia; Reali, Federico; Giordano, Giulia; Domenici, Enrico; Marchetti, Luca
Modeling the effect of immunotherapies on human castration-resistant prostate cancer
2021-01-01 Coletti, Roberta; Pugliese, Andrea; Marchetti, Luca
MOUSSE: Multi-omics using subject-specific signatures
2021-01-01 Fiorentino, G.; Visintainer, R.; Domenici, E.; Lauria, M.; Marchetti, L.
A Novel Hybrid Logic-ODE Modeling Approach to Overcome Knowledge Gaps
2021-01-01 Selvaggio, G.; Cristellon, S.; Marchetti, L.
Literature Mining and Mechanistic Graphical Modelling to Improve mRNA Vaccine Platforms
2021-01-01 Leonardelli, L.; Lofano, G.; Selvaggio, G.; Parolo, S.; Giampiccolo, S.; Tomasoni, D.; Domenici, E.; Priami, C.; Song, H.; Medini, D.; Marchetti, L.; Siena, E.
A quantitative systems pharmacology approach to support mRNA vaccine development and optimization
2021-01-01 Selvaggio, G.; Leonardelli, L.; Lofano, G.; Fresnay, S.; Parolo, S.; Medini, D.; Siena, E.; Marchetti, L.
History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications
2021-01-01 Azer, K.; Kaddi, C. D.; Barrett, J. S.; Bai, J. P. F.; Mcquade, S. T.; Merrill, N. J.; Piccoli, B.; Neves-Zaph, S.; Marchetti, L.; Lombardo, R.; Parolo, S.; Immanuel, S. R. C.; Baliga, N. S.
QSPcc reduces bottlenecks in computational model simulations
2021-01-01 Tomasoni, D.; Paris, A.; Giampiccolo, S.; Reali, F.; Simoni, G.; Marchetti, L.; Kaddi, C.; Neves-Zaph, S.; Priami, C.; Azer, K.; Lombardo, R.
Computational Analysis of Cytokine Release Following Bispecific T-Cell Engager Therapy: Applications of a Logic-Based Model
2022-01-01 Selvaggio, G.; Parolo, S.; Bora, P.; Leonardelli, L.; Harrold, J.; Mehta, K.; Rock, D. A.; Marchetti, L.
An age-dependent mathematical model of neurofilament trafficking in healthy conditions
2022-01-01 Paris, A.; Bora, P.; Parolo, S.; Monine, M.; Tong, X.; Eraly, S.; Masson, E.; Ferguson, T.; Mccampbell, A.; Graham, D.; Domenici, E.; Nestorov, I.; Marchetti, L.
A novel logical model of COVID-19 intracellular infection to support therapies development
2022-01-01 Piretto, E.; Selvaggio, G.; Bragantini, D.; Domenici, E.; Marchetti, L.
Mechanistic models of alpha-synuclein homeostasis for Parkinson's disease: A blueprint for therapeutic intervention
2022-01-01 Righetti, Elena; Antonello, Alice; Marchetti, Luca; Domenici, Enrico; Reali, Federico
A model-based framework to identify optimal administration protocols for immunotherapies in castration-resistance prostate cancer
2022-01-01 Coletti, R.; Pugliese, A.; Lunardi, A.; Caffo, O.; Marchetti, L.
Digital Twins and Virtual Populations: Applications in Quantitative Systems Pharmacology
2023-01-01 Reali, Federico; Paris, Alessio; Giampiccolo, Stefano; Righetti, Elena; Marchetti, Luca
A pediatric quantitative systems pharmacology model of neurofilament trafficking in spinal muscular atrophy treated with the antisense oligonucleotide nusinersen
2023-01-01 Paris, A.; Bora, P.; Parolo, S.; Maccannell, D.; Monine, M.; van der Munnik, N.; Tong, X.; Eraly, S.; Berger, Z.; Graham, D.; Ferguson, T.; Domenici, E.; Nestorov, I.; Marchetti, L.
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