Signalling through the JAK-STAT pathway in the developing brain.

The JAK-STAT (Janus kinase-signal transducer and activator of transcription) signalling pathway that is stimulated by cytokines has been much investigated in haematopoietic cells, but recent data indicate that this pathway is also present and active during neuronal and glial differentiation. Furthermore, it is now clear that growth factors other than the classical cytokines can act through this pathway and that physiological inhibitors of this signalling cascade exist. Thus, the JAKs, the STATs and their specific inhibitors could be molecules with important roles in the CNS.



Titolo: Signalling through the JAK-STAT pathway in the developing brain.
Autori: Cattaneo, E; Conti, Luciano; De Fraja, C.
Autori Unitn: 
Conti, Luciano
mostra contributor esterni 
Titolo del periodico: TRENDS IN NEUROSCIENCES
Anno di pubblicazione: 1999
Numero e parte del fascicolo: 8
Codice identificativo Scopus: 2-s2.0-0033179137
Codice identificativo Pubmed: 10407422
Codice identificativo ISI: WOS:000081712800012
Digital Object Identifier (DOI): http://dx.doi.org/10.1016/S0166-2236(98)01378-2
Handle: http://hdl.handle.net/11572/99157
Appare nelle tipologie:03.1 Articolo su rivista (Journal article)

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