CINECA IRIS Institutional Research Information System
IRIS è l'Anagrafe della ricerca dell'Università degli Studi di Trento, e ha lo scopo di raccogliere, documentare, conservare e diffondere, anche ad accesso aperto, la produzione scientifica degli autori afferenti all'Università degli Studi di Trento.
EnglishNSC systems present unique opportunities that are starting to be successfully explored for genetic and chemical screening. These systems provide the possibility of identifying and optimizing molecules/drugs that could lead to the tighter control in self-renewal and lineage specification of NSCs as well as their functional maturation. This could be crucial in moving forward NSC-based therapies. It is expected that recent advances in the method of producing NSCs from patient-specific human induced pluripotent stem (iPS) cells and in the technologies to grow them in vitro, while preserving their full developmental potential, will allow a full exploitation of NSCs both in drug discovery programs and in predictive toxicology studies.
| Titolo: | Neural stem cells as tools for drug discovery: novel platforms and approaches. | |
| Autori: | T., Gorba; Conti, Luciano | |
| Autori Unitn: | ||
| Titolo del periodico: | EXPERT OPINION ON DRUG DISCOVERY | |
| Anno di pubblicazione: | 2013 | |
| Numero e parte del fascicolo: | 9 | |
| Codice identificativo Scopus: | 2-s2.0-84883044632 | |
| Codice identificativo Pubmed: | 23725548 | |
| Codice identificativo WOS: | WOS:000323502200004 | |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1517/17460441.2013.805199 | |
| Handle: | http://hdl.handle.net/11572/99119 | |
| Appare nelle tipologie: | 03.1 Articolo su rivista (Journal article) |
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