The application of T2*-weighted gradient and spin-echo (GRASE) imaging was investigated as a method for blood oxygenation level-dependent (BOLD)- based functional magnetic resonance imaging (fMRI). The displaced-echo method was implemented to produce single-shot T2*-weighted GRASE images. This technique removes the requirement that the Carr-Purcell Meiboom-Gill (CPMG) condition be fulfilled. T2*-weighted GRASE images that are free from interference artifacts can thus be obtained, hence allowing the possibility of using single-shot GRASE for BOLD-based functional imaging. The method was demonstrated at 3 T and gave robust and reproducible activation-induced signal changes.
Functional MRI of the human brain with grase-based bold contrast
Jovicich, Jorge;
1999-01-01
Abstract
The application of T2*-weighted gradient and spin-echo (GRASE) imaging was investigated as a method for blood oxygenation level-dependent (BOLD)- based functional magnetic resonance imaging (fMRI). The displaced-echo method was implemented to produce single-shot T2*-weighted GRASE images. This technique removes the requirement that the Carr-Purcell Meiboom-Gill (CPMG) condition be fulfilled. T2*-weighted GRASE images that are free from interference artifacts can thus be obtained, hence allowing the possibility of using single-shot GRASE for BOLD-based functional imaging. The method was demonstrated at 3 T and gave robust and reproducible activation-induced signal changes.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione
