A four-nucleon calculation of the total He-4 photodisintegration cross section is performed. The full final-state interaction is taken into account for the first time. This is achieved via the method of the Lorentz integral transform. Semirealistic NN interactions are employed. Different from the known partial two-body He-4(gamma, n)He-3 and He-4(gamma, p)H-3 cross sections our total cross section exhibits a pronounced giant resonance. Thus, in contrast to older (gamma, np) data, we predict quite a strong contribution of the (gamma, np) channel at the giant resonance peak energy.
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