A woman hemophilia carrier with life-threatening esophageal varices and a severe hemophiliac male: A comparison of two different case reports and a brief description of literature

Introduction: Women hemophilia carriers (WHCs) are usually considered at low bleeding risk, but now this perception changed. WHCs previous treated with plasma-derived could have contracted post-transfusion HCV infection. Esophageal varices are one a lifethreatening complication of end-stage liver disease, HCV-related. Methods: A comparison between a case of a WHC with lifethreatening esophageal varices needing emergency treatment with that of a severe male. Results: No differences in terms of symptoms, treatment, and longterm prophylaxis between hemophilia patient and WHC were found. Conclusion: In WHCs, a management like that performed in hemophiliac males is necessary to reduce bleeding risk, and a prophylaxis should be early started.