Potassium-enriched depolarizing arrest (DA) is still the worldwide accepted method for myocardial protection. Despite animal models have demonstrated superior protection with no-potassium polarizing arrest (PA), and clinical studies reported lower perioperative myocardial enzymatic release, intra-cellular effects of PA vs DA in human myocardial specimens are still ill-defined.
Effects of polarizing microplegia vs standard high-potassium depolarizing microplegia on intracellular metabolism, pro-survival kinases, and apoptosis in humans / Gandhi, K., Rungatscher, A., Hallström, S., Tessari, M., Linardi, D., Milani, E., Vinten Johansen, J., Dobson, G.P., Onotrati, F., Mazzucco, A., Faggian, G.. - In: EUROPEAN SURGERY. - ISSN 1682-8631. - STAMPA. - 46:1(2014), pp. s10-s10. [10.1007/s10353-013-0244-6]
Effects of polarizing microplegia vs standard high-potassium depolarizing microplegia on intracellular metabolism, pro-survival kinases, and apoptosis in humans
Rungatscher, A.;Tessari, M.;
2014-01-01
Abstract
Potassium-enriched depolarizing arrest (DA) is still the worldwide accepted method for myocardial protection. Despite animal models have demonstrated superior protection with no-potassium polarizing arrest (PA), and clinical studies reported lower perioperative myocardial enzymatic release, intra-cellular effects of PA vs DA in human myocardial specimens are still ill-defined.| File | Dimensione | Formato | |
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