Background Psychosis rates are higher among some migrant groups. We hypothesized that psychosis in migrants is associated with cumulative social disadvantage during different phases of migration. Methods We used data from the EUropean Network of National Schizophrenia Networks studying Gene-Environment Interactions (EU-GEI) case-control study. We defined a set of three indicators of social disadvantage for each phase: Pre-migration, migration and post-migration. We examined whether social disadvantage in the pre- A nd post-migration phases, migration adversities, and mismatch between achievements and expectations differed between first-generation migrants with first-episode psychosis and healthy first-generation migrants, and tested whether this accounted for differences in odds of psychosis in multivariable logistic regression models. Results In total, 249 cases and 219 controls were assessed. Pre-migration (OR 1.61, 95% CI 1.06-2.44, p = 0.027) and post-migration social disadvantages...
Migration history and risk of psychosis: results from the multinational EU-GEI study / Tarricone, Ilaria; D'Andrea, Giuseppe; Jongsma, Hannah E; Tosato, Sarah; Gayer-Anderson, Charlotte; Stilo, Simona A; Suprani, Federico; Iyegbe, Conrad; Van Der Ven, Els; Quattrone, Diego; Di Forti, Marta; Velthorst, Eva; Rossi Menezes, Paulo; Arango, Celso; Parellada, Mara; Lasalvia, Antonio; La Cascia, Caterina; Ferraro, Laura; Bobes, Julio; Bernardo, Miguel; Sanjuán, Iulio; Santos, Jose Luis; Arrojo, Manuel; Del-Ben, Cristina Marta; Tripoli, Giada; Llorca, Pierre-Michel; De Haan, Lieuwe; Selten, Jean-Paul; Tortelli, Andrea; Szöke, Andrei; Muratori, Roberto; Rutten, Bart P; Van Os, Jim; Jones, Peter B; Kirkbride, James B; Berardi, Domenico; Murray, Robin M; Morgan, Craig. - In: PSYCHOLOGICAL MEDICINE. - ISSN 0033-2917. - STAMPA. - 52:14(2022), pp. 2972-2984. [10.1017/S003329172000495X]
Migration history and risk of psychosis: results from the multinational EU-GEI study
Lasalvia, Antonio;
2022-01-01
Abstract
Background Psychosis rates are higher among some migrant groups. We hypothesized that psychosis in migrants is associated with cumulative social disadvantage during different phases of migration. Methods We used data from the EUropean Network of National Schizophrenia Networks studying Gene-Environment Interactions (EU-GEI) case-control study. We defined a set of three indicators of social disadvantage for each phase: Pre-migration, migration and post-migration. We examined whether social disadvantage in the pre- A nd post-migration phases, migration adversities, and mismatch between achievements and expectations differed between first-generation migrants with first-episode psychosis and healthy first-generation migrants, and tested whether this accounted for differences in odds of psychosis in multivariable logistic regression models. Results In total, 249 cases and 219 controls were assessed. Pre-migration (OR 1.61, 95% CI 1.06-2.44, p = 0.027) and post-migration social disadvantages...| File | Dimensione | Formato | |
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