In this prospective study, we analyzed 30 male infants with increased neonatal 17-hydroxyprogesterone (17OH-P) (patients) and for comparison 52 age-matched healthy babies (control subjects) with the aim of investigating the hypothalamic-pituitary-testis axis in the first 6 months of life. Although T, FSH, and LH levels were not significantly different in patients and control subjects, inhibin B was higher in patients than in control subjects. Therefore we suggest a clinical follow-up of these babies during childhood and puberty to verify the evolution of their condition. Copyright © 2010 American Society for Reproductive Medicine, Published by Elsevier Inc.
Possible andrologic markers in elevated neonatal 17-hydroxyprogesterone / Cavarzere, P., Vincenzi, M., Gaudino, R., Franceschi, R., Perlini, S., Camilot, M., Teofoli, F., Antoniazzi, F., Tat, L.. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - 94:6(2010), pp. 2350-2352. [10.1016/j.fertnstert.2010.04.040]
Possible andrologic markers in elevated neonatal 17-hydroxyprogesterone
Franceschi R.;
2010-01-01
Abstract
In this prospective study, we analyzed 30 male infants with increased neonatal 17-hydroxyprogesterone (17OH-P) (patients) and for comparison 52 age-matched healthy babies (control subjects) with the aim of investigating the hypothalamic-pituitary-testis axis in the first 6 months of life. Although T, FSH, and LH levels were not significantly different in patients and control subjects, inhibin B was higher in patients than in control subjects. Therefore we suggest a clinical follow-up of these babies during childhood and puberty to verify the evolution of their condition. Copyright © 2010 American Society for Reproductive Medicine, Published by Elsevier Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione
