Fully explicit stabilized multirate (mRKC) methods are well-suited for the numerical solution of large multiscale systems of stiff ordinary differential equations thanks to their improved stability properties. To demonstrate their efficiency for the numerical solution of stiff, multiscale, nonlinear parabolic PDE’s, we apply mRKC methods to the monodomain equation from cardiac electrophysiology. In doing so, we propose an improved version, specifically tailored to the monodomain model, which leads to the explicit exponential multirate stabilized (emRKC) method. Several numerical experiments are conducted to evaluate the efficiency of both mRKC and emRKC, while taking into account different finite element meshes (structured and unstructured) and realistic ionic models. The new emRKC method typically outperforms a standard implicit-explicit baseline method for cardiac electrophysiology. Code profiling and strong scalability results further demonstrate that emRKC is faster and inherently parallel without sacrificing accuracy.

Explicit stabilized multirate methods for the monodomain model in cardiac electrophysiology / Rosilho de Souza, Giacomo; Grote, Marcus J.; Pezzuto, Simone; Krause, Rolf. - In: ESAIM. MATHEMATICAL MODELLING AND NUMERICAL ANALYSIS. - ISSN 2822-7840. - 58:6(2024), pp. 2225-2254. [10.1051/m2an/2024030]

Explicit stabilized multirate methods for the monodomain model in cardiac electrophysiology

Simone Pezzuto;
2024-01-01

Abstract

Fully explicit stabilized multirate (mRKC) methods are well-suited for the numerical solution of large multiscale systems of stiff ordinary differential equations thanks to their improved stability properties. To demonstrate their efficiency for the numerical solution of stiff, multiscale, nonlinear parabolic PDE’s, we apply mRKC methods to the monodomain equation from cardiac electrophysiology. In doing so, we propose an improved version, specifically tailored to the monodomain model, which leads to the explicit exponential multirate stabilized (emRKC) method. Several numerical experiments are conducted to evaluate the efficiency of both mRKC and emRKC, while taking into account different finite element meshes (structured and unstructured) and realistic ionic models. The new emRKC method typically outperforms a standard implicit-explicit baseline method for cardiac electrophysiology. Code profiling and strong scalability results further demonstrate that emRKC is faster and inherently parallel without sacrificing accuracy.
2024
6
Rosilho de Souza, Giacomo; Grote, Marcus J.; Pezzuto, Simone; Krause, Rolf
Explicit stabilized multirate methods for the monodomain model in cardiac electrophysiology / Rosilho de Souza, Giacomo; Grote, Marcus J.; Pezzuto, Simone; Krause, Rolf. - In: ESAIM. MATHEMATICAL MODELLING AND NUMERICAL ANALYSIS. - ISSN 2822-7840. - 58:6(2024), pp. 2225-2254. [10.1051/m2an/2024030]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/442124
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