This study aimed at developing a formulation to link the microscopic structure and macroscopic mechanics of a fbrous electrospun scafold flled with a hydrogel for use as an epicardial patch for local support of the infarcted heart. This study demonstrates the feasibility of homogenization techniques to represent complex multiscale structural features in a simplifed but meaningful and efective manner.
Micromechanical Homogenization of a Hydrogel-Filled Electrospun Scaffold for Tissue-Engineered Epicardial Patching of the infarcted Heart: A Feasibility Study / Sack, Kevin L.; Mandel, Nicolas; Pugno, Nicola M.; Bezuidenhout, Deon; Limbert, Georges; Moscato, Francesco; Davies, Neil H.; Franz, Thomas; Abdalrahman, Tamer. - In: MECCANICA. - ISSN 0025-6455. - 58:8(2023), pp. 1641-1655. [10.1007/s11012-023-01681-2]
Micromechanical Homogenization of a Hydrogel-Filled Electrospun Scaffold for Tissue-Engineered Epicardial Patching of the infarcted Heart: A Feasibility Study
Pugno, Nicola M.;
2023-01-01
Abstract
This study aimed at developing a formulation to link the microscopic structure and macroscopic mechanics of a fbrous electrospun scafold flled with a hydrogel for use as an epicardial patch for local support of the infarcted heart. This study demonstrates the feasibility of homogenization techniques to represent complex multiscale structural features in a simplifed but meaningful and efective manner.| File | Dimensione | Formato | |
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