Objectives: To compare respiratory system compliance (Crs) calculation during controlled mechanical ventilation (MV) and, subsequently, during assisted MV. Design: This is a single-center, retrospective, observational study. Setting: This study was conducted on patients admitted to Neuro-ICU of Niguarda Hospital (tertiary referral hospital). Patients: We analyzed every patient greater than or equal to 18 years old having a Crs measurement in controlled and in assisted MV within 60 minutes. Plateau pressure (Pplat) was considered reliable if it was deemed visually stable for at least 2 seconds. Interventions: Inspiratory pause was incorporated to detect Pplat in controlled and assisted MV. Calculation of Crs and driving pressure were achieved. Measurements and main results: A total of 101 patients were studied. An acceptable agreement was found (Bland-Altman plot bias -3.9, level of agreement upper 21.6, lower -29.6). Crs in assisted MV was 64.1 (52.6-79.3) and in controlled MV it was 61.2 (50-71.2) mL/cm H2o (p = 0.006). No statistical difference was found in Crs (assisted vs controlled MV) when peak pressure was lower than Pplat nor when peak pressure was higher than Pplat. Conclusions: A Pplat visually stable for at least 2 seconds leads to reliable Crs calculation during assisted MV.

Reliability of Respiratory System Compliance Calculation During Assisted Mechanical Ventilation: A Retrospective Study / Bastia, Luca; Amendolagine, Liliana; Pozzi, Federico; Carenini, Stefano; Cipolla, Cristiana; Curto, Francesco; Bellani, Giacomo; Fumagalli, Roberto; Chieregato, Arturo. - In: CRITICAL CARE MEDICINE. - ISSN 0090-3493. - 51:10(2023), pp. E201-E205. [10.1097/CCM.0000000000005964]

Reliability of Respiratory System Compliance Calculation During Assisted Mechanical Ventilation: A Retrospective Study

Bellani, Giacomo;
2023-01-01

Abstract

Objectives: To compare respiratory system compliance (Crs) calculation during controlled mechanical ventilation (MV) and, subsequently, during assisted MV. Design: This is a single-center, retrospective, observational study. Setting: This study was conducted on patients admitted to Neuro-ICU of Niguarda Hospital (tertiary referral hospital). Patients: We analyzed every patient greater than or equal to 18 years old having a Crs measurement in controlled and in assisted MV within 60 minutes. Plateau pressure (Pplat) was considered reliable if it was deemed visually stable for at least 2 seconds. Interventions: Inspiratory pause was incorporated to detect Pplat in controlled and assisted MV. Calculation of Crs and driving pressure were achieved. Measurements and main results: A total of 101 patients were studied. An acceptable agreement was found (Bland-Altman plot bias -3.9, level of agreement upper 21.6, lower -29.6). Crs in assisted MV was 64.1 (52.6-79.3) and in controlled MV it was 61.2 (50-71.2) mL/cm H2o (p = 0.006). No statistical difference was found in Crs (assisted vs controlled MV) when peak pressure was lower than Pplat nor when peak pressure was higher than Pplat. Conclusions: A Pplat visually stable for at least 2 seconds leads to reliable Crs calculation during assisted MV.
2023
10
Bastia, Luca; Amendolagine, Liliana; Pozzi, Federico; Carenini, Stefano; Cipolla, Cristiana; Curto, Francesco; Bellani, Giacomo; Fumagalli, Roberto; C...espandi
Reliability of Respiratory System Compliance Calculation During Assisted Mechanical Ventilation: A Retrospective Study / Bastia, Luca; Amendolagine, Liliana; Pozzi, Federico; Carenini, Stefano; Cipolla, Cristiana; Curto, Francesco; Bellani, Giacomo; Fumagalli, Roberto; Chieregato, Arturo. - In: CRITICAL CARE MEDICINE. - ISSN 0090-3493. - 51:10(2023), pp. E201-E205. [10.1097/CCM.0000000000005964]
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