The catalytic properties of chitosan aerogel for the direct asymmetric aldol reaction in water assisted by various surfac- tants and acid co-catalysts have been evaluated by em- ploying a range of donor and acceptor systems. A beneficial effect on both the yields and enantioselectivities was observed, and the combination of surfactants and acid co-catalysts has proven particularly useful in the case of heterocyclic ketone donors.
Chitosan Aerogel Beads as a Heterogeneous Organocatalyst for the Asymmetric Aldol Reaction in the Presence of Water: an Assessment of the Effect of Additives / Gioia, Claudio; Ricci, ALFREDO MARCO; Bernardi, Luca; K., Bourahla; N., Tanchoux; M., Robitzer; F., Quignard. - In: EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. - ISSN 1434-193X. - STAMPA. - 2013:(2013), pp. 588-594. [10.1002/ejoc.201201187]
Chitosan Aerogel Beads as a Heterogeneous Organocatalyst for the Asymmetric Aldol Reaction in the Presence of Water: an Assessment of the Effect of Additives
GIOIA, CLAUDIO;
2013-01-01
Abstract
The catalytic properties of chitosan aerogel for the direct asymmetric aldol reaction in water assisted by various surfac- tants and acid co-catalysts have been evaluated by em- ploying a range of donor and acceptor systems. A beneficial effect on both the yields and enantioselectivities was observed, and the combination of surfactants and acid co-catalysts has proven particularly useful in the case of heterocyclic ketone donors.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione
