Introduction More than 300million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI.Methods and analysis EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI.Ethics and dissemination EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Munster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials.
EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial / Raphael, Weiss; Khaschayar, Saadat-Gilani; Laura, Kerschke; Carola, Wempe; Melanie, Meersch; Zarbock, ; Hichem Makhloufi, Alexander; Cherak, Anis; Lakhel Ghanem, Lamine; Gouaglia, Zohier; Nasrine Guadouri, Dina; Naouel Hama, Fayrouz; Kara, Mustafa; Saadi, Omayma; Sakhraoui, Rachida; Bourou, Fadila; Cherifi, Abdelhadi; Ghania Sadaoui, Rahmoune; Ouyahia, Amel; Ouahab, Ilhem; Bouaoud, Souad; Abdoun, Meriem; Tidjane, Anisse; Tabeti, Benali; Boudjenan-Serradj, Nabil; Jose Pérez Rivera, Carlos; Cabrer, Paulo; Corso, Julián; Pablo García, Juan; Idarraga, Sharon; Montoya, Christopher; Figueroa, Rafael; Aldana, Eduar; Alejandra Torrado, María; Peng, Ke; Ma, Zheng-Min; Yang, Yu-Fan; Zhu, Ya-Juan; Sklienka, Peter; Frelich, Michal; Jarkulis, Vojtech; Sevcik, Pavel; Vodicka, Vojtech; Gamal Elbahnasawy, Mohamed; Elsalhawy, Shady; Motawea, Sara; Othman, Zeinab; Sahma, Mohamed; Mahmoud Nafea, Ahmed; Ahmed, Nermin; Ali Attia, Doaa; Maher Emara, Moataz; Mamdouh Bonna, Mohamed; Ahmed Gabr, Mohamed; Ismail Tarbay, Amany; Abdelmonaem Abdehaleem, Ibrahim; Elsayed Mohamed, Esraa; Mahmoud Eldeeb, Amr; Mohamed Abbas, Ahmed; Ashraf Magdy, John; Hassan Hamed, Zyad; Mostafa Esmaeil Osman, Hany; Samy Abbas, Mostafa; Joannes-Boyau, Oliver; Barraud, Nicolas; Berthelot, Corentin; Camus, Thibault; Dahmi, Anissa; Defaye, Mylène; Derville, Sébastien; El-Boustani, Younes; Deloge, Elsa; Jacob, Hélène; Monziols, Simon; Priem, Fred; Robin, Jean-Jacques; Legros, Vincent; Floch, Therry; Muccio, Salvatore; Geneve, Claire; Lim Legouge, Marie; Tao Mauny, Stéphanie; Mfam, Willy; Pascot, Léa; Aveline, Christophe; Chartier, Mireille; Duteurtre, Benjamin; Francois Gautier, Jean; Le Cousin, Aidren; Vautier, Pierre; Nadaud, Julien; Begel, Nathalie; Chekirine, Claire-Annissa; Derlon, Vincent; Grein, Elodie; Lehair, Marie-Annick; Magazzeni, Laurent; Magazzeni, Philippe; Potter, Carsten; Roth, Catherine; Voivret, Florence; Rimmelé, Thomas; Cerro, Valérie; Suria, Stéphanie; Elmawieh, Jamil; Stoclin, Annabelle; Cirenei, Cédric; Andrieu, Gregoire; Couloumy, Sven; Falcone, Jeremy; Fajardy, Marion; Gagneuil, Arsène; Girardet, Emeline; Mazereeuw, Agnès; Ponsonnard, Sébastien; Egreteau, Pierre-Yves; Bertel, Mélanie; Bocher, Simon; Carn, Vanessa; Le Guen, Lenaïg; Le Loup, Guillaume; Lefevre, Montaine; Ichai, Carole; Diop, Amanita; Jean-Michel, Vanessa; Devlieger, Sylvie; Duthoit, Juliette; El Kadiri, Mohamed; Léger, Maxime; Cassisa, Viviane; Lasocki, Sigismond; Masson, Charline; Rineau, Emmanuel; Verrier, Pierre; Coquerel, Axel; Montravers, Philippe; Atchade, Enora; Rochon, Charles-Edouard; Delerue, Céline; Quentin, Vidal; Latry, Vanessa; Queixalos, Nina; Cottenceau, Vincent; Braun, Thierry; Bouzoubaa, Saad; Christ, Basile; Geiger, Audrey; Gomille, Joachim; Kieffer, Vianney; Mangeant, Simone; Prochilo, Christelle; Schmitt, Christian; Skwirba, Stefan; Grand, Hubert; Boury, Frédérique; Mayeur, Nicolas; Pasquie, Marie; Garçon, Pierre; Bruckert, Vincent; Arnould, Vincent; Bonciu, Mona; Chapelle, Thibault; Facchino, Luc; Fagot-Gandet, Florence; Iachim, Andrea; Mannu, Elena; Perus, Olivier; Plattier, Rémi; Rozier, Romain; Pradel, Gaël; Boudinaud, Michel; Hausermann, Marie-Hélène; Hue Nguyen, My; Ramorasata, Andersen; Barreau, Amélie; Boivin, Anne-Hélène; Ravry, Céline; Mottard, Nicolas; Beuvelot, Johanne; Prunier Bossion, Florence; Desebbe, Olivier; Zarbock, Alexander; Dörr, Christian; Caspar von Groote, Thilo; Küllmar, Mira; Massoth, Christina; Meersch, Melanie; Saadat-Gilani, Khaschayar; Weiss, Raphael; Wempe, Carola; Ziemann, Sebastian; Grüßer, Linda; Kowark, Ana; Wittig, Pia; Brandenburger, Timo; Dimski, Thomas; Döhmen, Niklas; Huthmann, Laura; Kaierle, Daniela; Pelletier, Claude; Schleß, Manon; Hohn, Andreas; Cleophas, Sebastian; Haunhorst, Stephanie; Jansen, Marina; Schmitt, Alexandra; Soisch, Julia; Sturm, Kilian; Rosenberger, Peter; Bendig, Alexander; Flohr, Lena; Häberle, Helene; Hofmann, Pascal; Kuhle, Jonathan; Michaela Leser, Nora; Pfister, Kathrin; Prohaska, Stefanie; Sennholz, Franziska; Stetz, Lena; Weber, Kathrin; Stehr, Sebastian; Klaus, Stephan; Sadlo, Marco; Boschin, Matthias; Sengelhoff, Christian; Michael Göbel, Ulrich; Gerrit Haaker, Jan; Göttker, Carina-Kristin; Gründel, Matthias; Heringlake, Matthias; Baumgärtel, Romina; Berggren, Astrid; Gülzow, Madeleine; Muras, Lennart; Paarmann, Hauke; Thal, Serge; Bentley, Alexander; El-Masri, Dschamil; Sebastiani, Anne; Arnaoutoglou, Eleni; Ntalouka, Maria; Stratigopoulou, Paula; Analytis, Anastasia; Mavrommatis, Efthymios; Tzimas, Petros; Karakosta, Agathi; Pantazi, Danai; Dimakopoulou, Antonia; Dimitropoulou, Katerina; Ioannidis, Orestis; Jalaawiy, Humam; Anwar, Aeshah; Talib Hashim, Hashim; Imad Rasheed Aldawoody, Hogir; Cortegiani, Andrea; Catalisano, Giulia; Ingoglia, Gilia; Ippolito, Mariachiara; De Rosa, Silvia; Cattin, Lucia; Bianchin, Andrea; Barone, Marisa; Paternoster, Gianluca; Lucio Cutuli, Salvatore; Russo, Andrea; Sollazzi, Liliana; Cascarano, Laura; Antonelli, Massimo; Aceto, Paola; Romanò, Bruno; Spadaro, Savino; Francesco Tripodi, Vincenzo; Rossi, Michele; Scappatura, Rosamaria; Cristina Vadalà, Maria; Fiume, Diego; Teresa Strano, Maria; Oddo, Giulia; Santorsola, Clemente; Abu Hussain, Bilal; Raed Alnaser, Adnan; Hassouneh Ghassan, Anas; Hasanein, Khaled; Theab, Mohammed; Shin, Seokyung; Jung, Seungho; Lee, Kyuho; Mee Jung, Sung; Baek, Jongyoon; K Elhadi, Muhammed; Abuzeid, Issa; Albaraesi, Mohammed; Aldressi, Sarah; Khalel, Wegdan; Abdulwahed, Eman; Abdulhamid Ashur Abujrad, Akram; Almaghrabi, Amer; Mohammed Alteleeb, Muhand; Ahmed Ali Alshareea, Entisar; Isa Biala, Marwa; Deeknah, Abdulqudus; Ali Gheddim, Dooua; Ghmagh, Reem; Salih Ali AbuIkhrays, Nawras; Sinan, Marwa; Soula, Enas; Ghayth Bahroun, Sumayyah; Derwish, Khawla; Munir Mohamed, Aya; Sayed Younes, Eman; Al Islam Benjouira, Rayet; Aliwa, Mohamed; Abdullah Altashani, Najwa; Omar Alteb, Mohammed; Msherghi, Ahmed; Alagelli, Fatima; Albarouni, Sufyan; Albishti, Ahmed; Aljamal, Sarah; Alsori, Mohamed; Ekhuja, Taha; Elzwai, Suha; Ghula, Mohammed; Mustafa, Tahani; Tuwaib, Ahmed; Zriba, Haifa; Mahmoud Agilla, Hamza; Andriamahefa Rafanomezantsoa, Toky; Marie Camilleri Podesta, Anne; Mifsud Bonnici, Denise; Pirotta, Tiziana; Adrián Gasca López, Gilberto; Mojsova Mijovska, Maja; Davitkovska, Tatjana; Gavrilovska, Aleksandra; Lukikj, Sanja; Vesova, Marija; Zafirova, Dina; Amro, Sarah; F Hajjaj, Baraa N; Alkhazendar, Muawia; Barakat, Yousuf; Abdulaziz Elejla, Sewar; Elhissi, Ahmed; Khader, Ahmed; Salem, Ali; de Freitas Regufe, Rita; Filipe de Oliveira Eloy, André; Marisa Neto Cordeiro Perdigão, Lisbete; Grigoriev, Evgeny; Ivkin, Artem; Kornelyuk, Roman; Yaroustovsky, Michael; Abramyan, Marina; Komardina, Ekaterina; Lesteva, Nataliya; Aybazova, Medina; Kumykova, Elmira; Lesina, Svetlana; Rybakov, Gennady; Shestov, Alexey; Ahmad Ahmad Barmou, Abdulnaser; Lotfi Altayeb Ahmed, Bushra; Mohammad Eliyas, Aisha; Emadeldin, Yousra; Kaserer, Alexander; Castellucci, Clara; Rössler, Julian; Akbas, Samira; Möller Petrun, Andreja; Gregorcic, Irena; Sok, Vesna; Čičak, Roman; Bárcena, Elizabeth; Guisado, Antonio; Wi, Ismail; Ripollés Melchor, Javier; Becerra-Bolaños, Ángel; Cabrera-Doreste, Sergio; Domínguez-Arbelo, Ancor; Candelaria Delgado-Alonso, María; Muiño-Palomar, Virginia; Rodríguez-Pérez, Aurelio; Mata Estévez, Javier; Begona Covas Munoz, Maria; Mulet Matas, Juan; Perez Palao, Sara; Dolores Mira Quirós, Maria; Cezara Teslev, Alisia; Garcia Alvarez, Mercedes; Argilaga, Marga; Campos, María; Bainac, Albert; Batalla, Astrid; Garcia Alvarez, Mercedes; Giné, Marta; Herránz, Gracia; Hinojal, Ignacio; Logroño Ejea, Margarita; de la Rosa Ruiz, Noelia; Gastaca Abasolo, María; Rosario Houhton Acuna, Carla; Iriarte Zaranton, Ibai; Mendigurenmurua, Ana; José Munoz Sanz, María; Olea de la Fuente, Erika; Pilar Pérez Vaquero, María; Soto Iglesias, Ana; Ugarte Mieres, Ana; Urtiaga Urrestizala, Alaitz; Ferreira, Lourdes; Lobato, Félix; Aguado Sevilla, Marta; Erazo, Andres; Miró, Pere; Sabaté, Sergi; Vernetta, Diana; Castellano Paulis, Berta; Adell Perez, Anabel; Aseguinolaza Pagola, Marta; Castellano Paulis, Berta; delVal Peciña, Elena; Garmendia Odriozola, Ainhoa; Lopetegi Aizpurua, Amaia; Pavón Piquer, Olatz; Plou Garcia, Pilar; Ortega Rezola, Paula; Osorio Lopez, Antia; de la Calle Gil, Isabel; Navarro Casado, Rosalía; Adamove, Peter; Bayona Domenge, Roser; Miguel Blasco Blasco, Francho; Alexandra Rueda Villamizar, Adriana; Antonia Perelló Llaneras, Maria; Ignacio García-Sánchez, Jose; Fernandez Téllez, Laura; García Zamorano, Sara; Gijón Herreros, Natalia; Rodriguez Esteve, Andrea; Monedero Rodríguez, Pablo; García Trigo, Isabel; Alcaraz, Agustín; Lara Jiménez, Andrea; Rubio, Iñigo; García, Nuria; Callejas, Raquel; Manuel Candela Toha, Angel; Claros, Eli; Cobeta, Pilar; Crespo, Pascual; Dorado, Trini; Elías, Elena; Felices, Javier; Gil, Diego; Gómez, María; Mané, Nuria; Martín, María; Martínez, Adolfo; Pereira, Lucía; Balvis Noemí Samaranch, Alberto; Serrano, Ana; Tiscar, Carlos; Villahoz, Judith; Galán Menéndez, Patricia; Cardona, Elena; Conesa, Anna; Estepa, Veronica; Galán, Patricia; Llinares Espí, Laura; Loaiza Aldeán, Yuri; Manrique, Susana; Morales Ariza, Víctor; Villarino Villa, Laura; Saidahmed Mohamed Amed Suliman, Elfayadh; Hamid, Hytham; Mohamed Ibrahim, Ahmed; Mohamed Saeed, Modather; Sungur Mukadder, Orhan; Altun, Demet; Canbolat, Nur; Beril Dinçer, Müşerref; Özkan Seyhan, Tulay; Aktaş Yıldırım, Serap; İyigün, Müzeyyen; Yapıcı, Davut; Özdemir, Levent; Sagun, Aslinur; Boztug, Neval; Cetintas, Yesim; Dinc, Bora; Gündüz, Emel; Ünlügenç, Hakkı; Lafli Tunay, Demet; Karakaya, Deniz; Dost, Burhan; Komurcu, Ozgur; Korkmaz Dilmen, Özlem; Fatma Akcil, Eren; Korkmaz Dilmen, Özlem; Tunali, Yusuf; Ok, Gülay; Tok Alsina, Eda; Hakli, Özge; Polat, Cengiz; Turgut, Namigar; Kızılcık, Nurcan; Köner, Özge; Şen, Öznur; Aydin, Nurdan; Basaran, Burcu; Sertac Bingul, Emre; Gürkan, Yavuz; Darcin, Kamil; Ugur, Semra; Tolga Saracoglu, Kemal; Demir, Asli; 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EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial
Weiss, Raphael; Saadat-Gilani, Khaschayar; Kerschke, Laura; Wempe, Carola; Meersch, Melanie; Zarbock; Alexander Hichem Makhloufi; Anis Cherak; Lamine Lakhel Ghanem; Zohier Gouaglia; Dina Nasrine Guadouri; Fayrouz Naouel Hama; Mustafa Kara; Omayma Saadi; Rachida Sakhraoui; Fadila Bourou; Abdelhadi Cherifi; Rahmoune Ghania Sadaoui; Amel Ouyahia; Ilhem Ouahab; Souad Bouaoud; Meriem Abdoun; Anisse Tidjane; Benali Tabeti; Nabil Boudjenan-Serradj; Carlos Jose Pérez Rivera; Paulo Cabrer; Julián Corso; Juan Pablo García; Sharon Idarraga; Christopher Montoya; Rafael Figueroa; Eduar Aldana; María Alejandra Torrado; Ke Peng; Zheng-Min Ma; Yu-Fan Yang; Ya-Juan Zhu; Peter Sklienka; Michal Frelich; Vojtech Jarkulis; Pavel Sevcik; Vojtech Vodicka; Mohamed Gamal Elbahnasawy; Shady Elsalhawy; Sara Motawea; Zeinab Othman; Mohamed Sahma; Ahmed Mahmoud Nafea; Nermin Ahmed; Doaa Ali Attia; Moataz Maher Emara; Mohamed Mamdouh Bonna; Mohamed Ahmed Gabr; Amany Ismail Tarbay; Ibrahim Abdelmonaem Abdehaleem; Esraa Elsayed Mohamed; Amr Mahmoud Eldeeb; Ahmed Mohamed Abbas; John Ashraf Magdy; Zyad Hassan Hamed; Hany Mostafa Esmaeil Osman; Mostafa Samy Abbas; Oliver Joannes-Boyau; Nicolas Barraud; Corentin Berthelot; Thibault Camus; Anissa Dahmi; Mylène Defaye; Sébastien Derville; Younes El-Boustani; Elsa Deloge; Hélène Jacob; Simon Monziols; Fred Priem; Jean-Jacques Robin; Vincent Legros; Therry Floch; Salvatore Muccio; Claire Geneve; Marie Lim Legouge; Stéphanie Tao Mauny; Willy Mfam; Léa Pascot; Christophe Aveline; Mireille Chartier; Benjamin Duteurtre; Jean Francois Gautier; Aidren Le Cousin; Pierre Vautier; Julien Nadaud; Nathalie Begel; Claire-Annissa Chekirine; Vincent Derlon; Elodie Grein; Marie-Annick Lehair; Laurent Magazzeni; Philippe Magazzeni; Carsten Potter; Catherine Roth; Florence Voivret; Thomas Rimmelé; Valérie Cerro; Stéphanie Suria; Jamil Elmawieh; Annabelle Stoclin; Cédric Cirenei; Gregoire Andrieu; Sven Couloumy; Jeremy Falcone; Marion Fajardy; Arsène Gagneuil; Emeline Girardet; Agnès Mazereeuw; Sébastien Ponsonnard; Pierre-Yves Egreteau; Mélanie Bertel; Simon Bocher; Vanessa Carn; Lenaïg Le Guen; Guillaume Le Loup; Montaine Lefevre; Carole Ichai; Amanita Diop; Vanessa Jean-Michel; Sylvie Devlieger; Juliette Duthoit; Mohamed El Kadiri; Maxime Léger; Viviane Cassisa; Sigismond Lasocki; Charline Masson; Emmanuel Rineau; Pierre Verrier; Axel Coquerel; Philippe Montravers; Enora Atchade; Charles-Edouard Rochon; Céline Delerue; Vidal Quentin; Vanessa Latry; Nina Queixalos; Vincent Cottenceau; Thierry Braun; Saad Bouzoubaa; Basile Christ; Audrey Geiger; Joachim Gomille; Vianney Kieffer; Simone Mangeant; Christelle Prochilo; Christian Schmitt; Stefan Skwirba; Hubert Grand; Frédérique Boury; Nicolas Mayeur; Marie Pasquie; Pierre Garçon; Vincent Bruckert; Vincent Arnould; Mona Bonciu; Thibault Chapelle; Luc Facchino; Florence Fagot-Gandet; Andrea Iachim; Elena Mannu; Olivier Perus; Rémi Plattier; Romain Rozier; Gaël Pradel; Michel Boudinaud; Marie-Hélène Hausermann; My Hue Nguyen; Andersen Ramorasata; Amélie Barreau; Anne-Hélène Boivin; Céline Ravry; Nicolas Mottard; Johanne Beuvelot; Florence Prunier Bossion; Olivier Desebbe; Alexander Zarbock; Christian Dörr; Thilo Caspar von Groote; Mira Küllmar; Christina Massoth; Melanie Meersch; Khaschayar Saadat-Gilani; Raphael Weiss; Carola Wempe; Sebastian Ziemann; Linda Grüßer; Ana Kowark; Pia Wittig; Timo Brandenburger; Thomas Dimski; Niklas Döhmen; Laura Huthmann; Daniela Kaierle; Claude Pelletier; Manon Schleß; Andreas Hohn; Sebastian Cleophas; Stephanie Haunhorst; Marina Jansen; Alexandra Schmitt; Julia Soisch; Kilian Sturm; Peter Rosenberger; Alexander Bendig; Lena Flohr; Helene Häberle; Pascal Hofmann; Jonathan Kuhle; Nora Michaela Leser; Kathrin Pfister; Stefanie Prohaska; Franziska Sennholz; Lena Stetz; Kathrin Weber; Sebastian Stehr; Stephan Klaus; Marco Sadlo; Matthias Boschin; Christian Sengelhoff; Ulrich Michael Göbel; Jan Gerrit Haaker; Carina-Kristin Göttker; Matthias Gründel; Matthias Heringlake; Romina Baumgärtel; Astrid Berggren; Madeleine Gülzow; Lennart Muras; Hauke Paarmann; Serge Thal; Alexander Bentley; Dschamil El-Masri; Anne Sebastiani; Eleni Arnaoutoglou; Maria Ntalouka; Paula Stratigopoulou; Anastasia Analytis; Efthymios Mavrommatis; Petros Tzimas; Agathi Karakosta; Danai Pantazi; Antonia Dimakopoulou; Katerina Dimitropoulou; Orestis Ioannidis; Humam Jalaawiy; Aeshah Anwar; Hashim Talib Hashim; Hogir Imad Rasheed Aldawoody; Andrea Cortegiani; Giulia Catalisano; Gilia Ingoglia; Mariachiara Ippolito; Silvia De Rosa ;Lucia Cattin; Andrea Bianchin; Marisa Barone; Gianluca Paternoster; Salvatore Lucio Cutuli; Andrea Russo; Liliana Sollazzi; Laura Cascarano; Massimo Antonelli; Paola Aceto; Bruno Romanò; Savino Spadaro; Vincenzo Francesco Tripodi; Michele Rossi; Rosamaria Scappatura; Maria Cristina Vadalà; Diego Fiume; Maria Teresa Strano; Giulia Oddo; Clemente Santorsola; Bilal Abu Hussain; Adnan Raed Alnaser; Anas Hassouneh Ghassan; Khaled Hasanein; Mohammed Theab; Seokyung Shin; Seungho Jung; Kyuho Lee; Sung Mee Jung; Jongyoon Baek; Muhammed K Elhadi; Issa Abuzeid; Mohammed Albaraesi; Sarah Aldressi; Wegdan Khalel; Eman Abdulwahed; Akram Abdulhamid Ashur Abujrad; Amer Almaghrabi; Muhand Mohammed Alteleeb; Entisar Ahmed Ali Alshareea; Marwa Isa Biala; Abdulqudus Deeknah; Dooua Ali Gheddim; Reem Ghmagh; Nawras Salih Ali AbuIkhrays; Marwa Sinan; Enas Soula; Sumayyah Ghayth Bahroun; Khawla Derwish; Aya Munir Mohamed; Eman Sayed Younes; Rayet Al Islam Benjouira; Mohamed Aliwa; Najwa Abdullah Altashani; Mohammed Omar Alteb; Ahmed Msherghi; Fatima Alagelli; Sufyan Albarouni; Ahmed Albishti; Sarah Aljamal; Mohamed Alsori; Taha Ekhuja; Suha Elzwai; Mohammed Ghula; Tahani Mustafa; Ahmed Tuwaib; Haifa Zriba; Hamza Mahmoud Agilla; Toky Andriamahefa Rafanomezantsoa; Anne Marie Camilleri Podesta; Denise Mifsud Bonnici; Tiziana Pirotta; Gilberto Adrián Gasca López; Maja Mojsova Mijovska; Tatjana Davitkovska; Aleksandra Gavrilovska; Sanja Lukikj; Marija Vesova; Dina Zafirova; Sarah Amro; Baraa N F Hajjaj; Muawia Alkhazendar; Yousuf Barakat; Sewar Abdulaziz Elejla; Ahmed Elhissi; Ahmed Khader; Ali Salem; Rita de Freitas Regufe; André Filipe de Oliveira Eloy; Lisbete Marisa Neto Cordeiro Perdigão; Evgeny Grigoriev; Artem Ivkin; Roman Kornelyuk; Michael Yaroustovsky; Marina Abramyan; Ekaterina Komardina; Nataliya Lesteva; Medina Aybazova; Elmira Kumykova; Svetlana Lesina; Gennady Rybakov; Alexey Shestov; Abdulnaser Ahmad Ahmad Barmou; Bushra Lotfi Altayeb Ahmed; Aisha Mohammad Eliyas; Yousra Emadeldin; Alexander Kaserer; Clara Castellucci; Julian Rössler; Samira Akbas; Andreja Möller Petrun; Irena Gregorcic; Vesna Sok; Roman Čičak; Elizabeth Bárcena; Antonio Guisado; Ismail Wi; Javier Ripollés Melchor; Ángel Becerra-Bolaños; Sergio Cabrera-Doreste; Ancor Domínguez-Arbelo; María Candelaria Delgado-Alonso; Virginia Muiño-Palomar; Aurelio Rodríguez-Pérez; Javier Mata Estévez; Maria Begona Covas Munoz; Juan Mulet Matas; Sara Perez Palao; Maria Dolores Mira Quirós; Alisia Cezara Teslev; Mercedes Garcia Alvarez; Marga Argilaga; María Campos; Albert Bainac; Astrid Batalla; Mercedes Garcia Alvarez; Marta Giné; Gracia Herránz; Ignacio Hinojal; Margarita Logroño Ejea; Noelia de la Rosa Ruiz; María Gastaca Abasolo; Carla Rosario Houhton Acuna; Ibai Iriarte Zaranton; Ana Mendigurenmurua; María José Munoz Sanz; Erika Olea de la Fuente; María Pilar Pérez Vaquero; Ana Soto Iglesias; Ana Ugarte Mieres; Alaitz Urtiaga Urrestizala; Lourdes Ferreira; Félix Lobato; Marta Aguado Sevilla; Andres Erazo; Pere Miró; Sergi Sabaté; Diana Vernetta; Berta Castellano Paulis; Anabel Adell Perez; Marta Aseguinolaza Pagola; Berta Castellano Paulis; Elena delVal Peciña; Ainhoa Garmendia Odriozola; Amaia Lopetegi Aizpurua; Olatz Pavón Piquer; Pilar Plou Garcia; Paula Ortega Rezola; Antia Osorio Lopez; Isabel de la Calle Gil; Rosalía Navarro Casado; Peter Adamove; Roser Bayona Domenge; Francho Miguel Blasco Blasco; Adriana Alexandra Rueda Villamizar; Maria Antonia Perelló Llaneras; Jose Ignacio García-Sánchez; Laura Fernandez Téllez; Sara García Zamorano; Natalia Gijón Herreros; Andrea Rodriguez Esteve; Pablo Monedero Rodríguez; Isabel García Trigo; Agustín Alcaraz; Andrea Lara Jiménez; Iñigo Rubio; Nuria García; Raquel Callejas; Angel Manuel Candela Toha; Eli Claros; Pilar Cobeta; Pascual Crespo; Trini Dorado; Elena Elías; Javier Felices; Diego Gil; María Gómez; Nuria Mané; María Martín; Adolfo Martínez; Lucía Pereira; Alberto Balvis Noemí Samaranch; Ana Serrano; Carlos Tiscar; Judith VillaHoz; Patricia Galán Menéndez; Elena Cardona; Anna Conesa; Veronica Estepa; Patricia Galán; Laura Llinares Espí; Yuri Loaiza Aldeán; Susana Manrique; Víctor Morales Ariza; Laura Villarino Villa; Elfayadh Saidahmed Mohamed Amed Suliman; Hytham Hamid; Ahmed Mohamed Ibrahim; Modather Mohamed Saeed; Orhan Sungur Mukadder; Demet Altun; Nur Canbolat; Müşerref Beril Dinçer; Tulay Özkan Seyhan; Serap Aktaş Yıldırım; Müzeyyen İyigün; Davut Yapıcı; Levent Özdemir; Aslinur Sagun; Neval Boztug; Yesim Cetintas; Bora Dinc; Emel Gündüz; Hakkı Ünlügenç; Demet Lafli Tunay; Deniz Karakaya; Burhan Dost; Ozgur Komurcu; Özlem Korkmaz Dilmen; Eren Fatma Akcil; Özlem Korkmaz Dilmen; Yusuf Tunali; Gülay Ok; Eda Tok Alsina; Özge Hakli; Cengiz Polat; Namigar Turgut; Nurcan Kızılcık; Özge Köner; Öznur Şen; Nurdan Aydin; Burcu Basaran; Emre Sertac Bingul; Yavuz Gürkan; Kamil Darcin; Semra Ugur; Kemal Tolga Saracoglu; Asli Demir; Özgök Aysegül; Eda Balci; Behic Girgin; Aygun Guler; Ümit Karadeniz; Nihal Özaslan; Yigit Özay Hülya; Namik Ozcan; Aysun Postaci; Mehmet Sahap; Nevriye Salman; Özlem Sağır; Bulent Atik; Murat Bicakcioglu; Hafize Fisun Demir; Ugün Fatih; Nazan Kocaoglu; Hüseyin Ilksen Toprak; Duygu Demiröz Aslan; Yusuf Ziya Colak; Mustafa Soner Ozcan; Mehmet Yilmaz; Umran Karaca; Sevtap Hekimoglu Sahin; Özlem Ersoy Karka; Gizem Demir Şenoğlu; Süheyla Erkoç Karadağ; Neslihan Alkis; Volkan Baytaş; Engin Erturk; Ali Akdogan; Ahmet Besir; Engin Erturk; Dilek Kutanis; Sedat Saylan; Ersagun Tugcugil; Pinar Ayvat; Berrin Günaydın; Beyza Mehri Büyükgebiz; Omer Faruk Boran; Feyza Calisir; Yavuz Orak; Bahar Kuvaki Balkan; Bahar Kuvaki Balkan; Sibel Büyükcoban; Erol Gökel; Sakize Ferim Günenc; Sule Özbilgin; Suna Göre; Selcan Akesen; Seda Cansabuncu; Natalia Momot; Anna Panchenko; Jean-Francois Pittet; Kristen Rutledge
2021-01-01
Abstract
Introduction More than 300million surgical procedures are performed each year. Acute kidney injury (AKI) is a common complication after major surgery and is associated with adverse short-term and long-term outcomes. However, there is a large variation in the incidence of reported AKI rates. The establishment of an accurate epidemiology of surgery-associated AKI is important for healthcare policy, quality initiatives, clinical trials, as well as for improving guidelines. The objective of the Epidemiology of Surgery-associated Acute Kidney Injury (EPIS-AKI) trial is to prospectively evaluate the epidemiology of AKI after major surgery using the latest Kidney Disease: Improving Global Outcomes (KDIGO) consensus definition of AKI.Methods and analysis EPIS-AKI is an international prospective, observational, multicentre cohort study including 10 000 patients undergoing major surgery who are subsequently admitted to the ICU or a similar high dependency unit. The primary endpoint is the incidence of AKI within 72 hours after surgery according to the KDIGO criteria. Secondary endpoints include use of renal replacement therapy (RRT), mortality during ICU and hospital stay, length of ICU and hospital stay and major adverse kidney events (combined endpoint consisting of persistent renal dysfunction, RRT and mortality) at day 90. Further, we will evaluate preoperative and intraoperative risk factors affecting the incidence of postoperative AKI. In an add-on analysis, we will assess urinary biomarkers for early detection of AKI.Ethics and dissemination EPIS-AKI has been approved by the leading Ethics Committee of the Medical Council North Rhine-Westphalia, of the Westphalian Wilhelms-University Munster and the corresponding Ethics Committee at each participating site. Results will be disseminated widely and published in peer-reviewed journals, presented at conferences and used to design further AKI-related trials.
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EPIdemiology of Surgery-Associated Acute Kidney Injury (EPIS-AKI): study protocol for a multicentre, observational trial / Raphael, Weiss; Khaschayar, Saadat-Gilani; Laura, Kerschke; Carola, Wempe; Melanie, Meersch; Zarbock, ; Hichem Makhloufi, Alexander; Cherak, Anis; Lakhel Ghanem, Lamine; Gouaglia, Zohier; Nasrine Guadouri, Dina; Naouel Hama, Fayrouz; Kara, Mustafa; Saadi, Omayma; Sakhraoui, Rachida; Bourou, Fadila; Cherifi, Abdelhadi; Ghania Sadaoui, Rahmoune; Ouyahia, Amel; Ouahab, Ilhem; Bouaoud, Souad; Abdoun, Meriem; Tidjane, Anisse; Tabeti, Benali; Boudjenan-Serradj, Nabil; Jose Pérez Rivera, Carlos; Cabrer, Paulo; Corso, Julián; Pablo García, Juan; Idarraga, Sharon; Montoya, Christopher; Figueroa, Rafael; Aldana, Eduar; Alejandra Torrado, María; Peng, Ke; Ma, Zheng-Min; Yang, Yu-Fan; Zhu, Ya-Juan; Sklienka, Peter; Frelich, Michal; Jarkulis, Vojtech; Sevcik, Pavel; Vodicka, Vojtech; Gamal Elbahnasawy, Mohamed; Elsalhawy, Shady; Motawea, Sara; Othman, Zeinab; Sahma, Mohamed; Mahmoud Nafea, Ahmed; Ahmed, Nermin; Ali Attia, Doaa; Maher Emara, Moataz; Mamdouh Bonna, Mohamed; Ahmed Gabr, Mohamed; Ismail Tarbay, Amany; Abdelmonaem Abdehaleem, Ibrahim; Elsayed Mohamed, Esraa; Mahmoud Eldeeb, Amr; Mohamed Abbas, Ahmed; Ashraf Magdy, John; Hassan Hamed, Zyad; Mostafa Esmaeil Osman, Hany; Samy Abbas, Mostafa; Joannes-Boyau, Oliver; Barraud, Nicolas; Berthelot, Corentin; Camus, Thibault; Dahmi, Anissa; Defaye, Mylène; Derville, Sébastien; El-Boustani, Younes; Deloge, Elsa; Jacob, Hélène; Monziols, Simon; Priem, Fred; Robin, Jean-Jacques; Legros, Vincent; Floch, Therry; Muccio, Salvatore; Geneve, Claire; Lim Legouge, Marie; Tao Mauny, Stéphanie; Mfam, Willy; Pascot, Léa; Aveline, Christophe; Chartier, Mireille; Duteurtre, Benjamin; Francois Gautier, Jean; Le Cousin, Aidren; Vautier, Pierre; Nadaud, Julien; Begel, Nathalie; Chekirine, Claire-Annissa; Derlon, Vincent; Grein, Elodie; Lehair, Marie-Annick; Magazzeni, Laurent; Magazzeni, Philippe; Potter, Carsten; Roth, Catherine; Voivret, Florence; 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Kuhle, Jonathan; Michaela Leser, Nora; Pfister, Kathrin; Prohaska, Stefanie; Sennholz, Franziska; Stetz, Lena; Weber, Kathrin; Stehr, Sebastian; Klaus, Stephan; Sadlo, Marco; Boschin, Matthias; Sengelhoff, Christian; Michael Göbel, Ulrich; Gerrit Haaker, Jan; Göttker, Carina-Kristin; Gründel, Matthias; Heringlake, Matthias; Baumgärtel, Romina; Berggren, Astrid; Gülzow, Madeleine; Muras, Lennart; Paarmann, Hauke; Thal, Serge; Bentley, Alexander; El-Masri, Dschamil; Sebastiani, Anne; Arnaoutoglou, Eleni; Ntalouka, Maria; Stratigopoulou, Paula; Analytis, Anastasia; Mavrommatis, Efthymios; Tzimas, Petros; Karakosta, Agathi; Pantazi, Danai; Dimakopoulou, Antonia; Dimitropoulou, Katerina; Ioannidis, Orestis; Jalaawiy, Humam; Anwar, Aeshah; Talib Hashim, Hashim; Imad Rasheed Aldawoody, Hogir; Cortegiani, Andrea; Catalisano, Giulia; Ingoglia, Gilia; Ippolito, Mariachiara; De Rosa, Silvia; Cattin, Lucia; Bianchin, Andrea; Barone, Marisa; Paternoster, Gianluca; Lucio Cutuli, Salvatore; Russo, Andrea; Sollazzi, Liliana; Cascarano, Laura; Antonelli, Massimo; Aceto, Paola; Romanò, Bruno; Spadaro, Savino; Francesco Tripodi, Vincenzo; Rossi, Michele; Scappatura, Rosamaria; Cristina Vadalà, Maria; Fiume, Diego; Teresa Strano, Maria; Oddo, Giulia; Santorsola, Clemente; Abu Hussain, Bilal; Raed Alnaser, Adnan; Hassouneh Ghassan, Anas; Hasanein, Khaled; Theab, Mohammed; Shin, Seokyung; Jung, Seungho; Lee, Kyuho; Mee Jung, Sung; Baek, Jongyoon; K Elhadi, Muhammed; Abuzeid, Issa; Albaraesi, Mohammed; Aldressi, Sarah; Khalel, Wegdan; Abdulwahed, Eman; Abdulhamid Ashur Abujrad, Akram; Almaghrabi, Amer; Mohammed Alteleeb, Muhand; Ahmed Ali Alshareea, Entisar; Isa Biala, Marwa; Deeknah, Abdulqudus; Ali Gheddim, Dooua; Ghmagh, Reem; Salih Ali AbuIkhrays, Nawras; Sinan, Marwa; Soula, Enas; Ghayth Bahroun, Sumayyah; Derwish, Khawla; Munir Mohamed, Aya; Sayed Younes, Eman; Al Islam Benjouira, Rayet; Aliwa, Mohamed; Abdullah Altashani, Najwa; Omar Alteb, Mohammed; Msherghi, Ahmed; Alagelli, Fatima; Albarouni, Sufyan; Albishti, Ahmed; Aljamal, Sarah; Alsori, Mohamed; Ekhuja, Taha; Elzwai, Suha; Ghula, Mohammed; Mustafa, Tahani; Tuwaib, Ahmed; Zriba, Haifa; Mahmoud Agilla, Hamza; Andriamahefa Rafanomezantsoa, Toky; Marie Camilleri Podesta, Anne; Mifsud Bonnici, Denise; Pirotta, Tiziana; Adrián Gasca López, Gilberto; Mojsova Mijovska, Maja; Davitkovska, Tatjana; Gavrilovska, Aleksandra; Lukikj, Sanja; Vesova, Marija; Zafirova, Dina; Amro, Sarah; F Hajjaj, Baraa N; Alkhazendar, Muawia; Barakat, Yousuf; Abdulaziz Elejla, Sewar; Elhissi, Ahmed; Khader, Ahmed; Salem, Ali; de Freitas Regufe, Rita; Filipe de Oliveira Eloy, André; Marisa Neto Cordeiro Perdigão, Lisbete; Grigoriev, Evgeny; Ivkin, Artem; Kornelyuk, Roman; Yaroustovsky, Michael; Abramyan, Marina; Komardina, Ekaterina; Lesteva, Nataliya; Aybazova, Medina; Kumykova, Elmira; Lesina, Svetlana; Rybakov, Gennady; Shestov, Alexey; Ahmad Ahmad Barmou, Abdulnaser; Lotfi Altayeb Ahmed, Bushra; Mohammad Eliyas, Aisha; Emadeldin, Yousra; Kaserer, Alexander; Castellucci, Clara; Rössler, Julian; Akbas, Samira; Möller Petrun, Andreja; Gregorcic, Irena; Sok, Vesna; Čičak, Roman; Bárcena, Elizabeth; Guisado, Antonio; Wi, Ismail; Ripollés Melchor, Javier; Becerra-Bolaños, Ángel; Cabrera-Doreste, Sergio; Domínguez-Arbelo, Ancor; Candelaria Delgado-Alonso, María; Muiño-Palomar, Virginia; Rodríguez-Pérez, Aurelio; Mata Estévez, Javier; Begona Covas Munoz, Maria; Mulet Matas, Juan; Perez Palao, Sara; Dolores Mira Quirós, Maria; Cezara Teslev, Alisia; Garcia Alvarez, Mercedes; Argilaga, Marga; Campos, María; Bainac, Albert; Batalla, Astrid; Garcia Alvarez, Mercedes; Giné, Marta; Herránz, Gracia; Hinojal, Ignacio; Logroño Ejea, Margarita; de la Rosa Ruiz, Noelia; Gastaca Abasolo, María; Rosario Houhton Acuna, Carla; Iriarte Zaranton, Ibai; Mendigurenmurua, Ana; José Munoz Sanz, María; Olea de la Fuente, Erika; Pilar Pérez Vaquero, María; Soto Iglesias, Ana; Ugarte Mieres, Ana; Urtiaga Urrestizala, Alaitz; Ferreira, Lourdes; Lobato, Félix; Aguado Sevilla, Marta; Erazo, Andres; Miró, Pere; Sabaté, Sergi; Vernetta, Diana; Castellano Paulis, Berta; Adell Perez, Anabel; Aseguinolaza Pagola, Marta; Castellano Paulis, Berta; delVal Peciña, Elena; Garmendia Odriozola, Ainhoa; Lopetegi Aizpurua, Amaia; Pavón Piquer, Olatz; Plou Garcia, Pilar; Ortega Rezola, Paula; Osorio Lopez, Antia; de la Calle Gil, Isabel; Navarro Casado, Rosalía; Adamove, Peter; Bayona Domenge, Roser; Miguel Blasco Blasco, Francho; Alexandra Rueda Villamizar, Adriana; Antonia Perelló Llaneras, Maria; Ignacio García-Sánchez, Jose; Fernandez Téllez, Laura; García Zamorano, Sara; Gijón Herreros, Natalia; Rodriguez Esteve, Andrea; Monedero Rodríguez, Pablo; García Trigo, Isabel; Alcaraz, Agustín; Lara Jiménez, Andrea; Rubio, Iñigo; García, Nuria; Callejas, Raquel; Manuel Candela Toha, Angel; Claros, Eli; Cobeta, Pilar; Crespo, Pascual; Dorado, Trini; Elías, Elena; Felices, Javier; Gil, Diego; Gómez, María; Mané, Nuria; Martín, María; Martínez, Adolfo; Pereira, Lucía; Balvis Noemí Samaranch, Alberto; Serrano, Ana; Tiscar, Carlos; Villahoz, Judith; Galán Menéndez, Patricia; Cardona, Elena; Conesa, Anna; Estepa, Veronica; Galán, Patricia; Llinares Espí, Laura; Loaiza Aldeán, Yuri; Manrique, Susana; Morales Ariza, Víctor; Villarino Villa, Laura; Saidahmed Mohamed Amed Suliman, Elfayadh; Hamid, Hytham; Mohamed Ibrahim, Ahmed; Mohamed Saeed, Modather; Sungur Mukadder, Orhan; Altun, Demet; Canbolat, Nur; Beril Dinçer, Müşerref; Özkan Seyhan, Tulay; Aktaş Yıldırım, Serap; İyigün, Müzeyyen; Yapıcı, Davut; Özdemir, Levent; Sagun, Aslinur; Boztug, Neval; Cetintas, Yesim; Dinc, Bora; Gündüz, Emel; Ünlügenç, Hakkı; Lafli Tunay, Demet; Karakaya, Deniz; Dost, Burhan; Komurcu, Ozgur; Korkmaz Dilmen, Özlem; Fatma Akcil, Eren; Korkmaz Dilmen, Özlem; Tunali, Yusuf; Ok, Gülay; Tok Alsina, Eda; Hakli, Özge; Polat, Cengiz; Turgut, Namigar; Kızılcık, Nurcan; Köner, Özge; Şen, Öznur; Aydin, Nurdan; Basaran, Burcu; Sertac Bingul, Emre; Gürkan, Yavuz; Darcin, Kamil; Ugur, Semra; Tolga Saracoglu, Kemal; Demir, Asli; 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[10.1136/bmjopen-2021-055705]
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Il report seguente simula gli indicatori relativi alla propria produzione scientifica in relazione alle soglie ASN 2023-2025 del proprio SC/SSD. Si ricorda che il superamento dei valori soglia (almeno 2 su 3) è requisito necessario ma non sufficiente al conseguimento dell'abilitazione. La simulazione si basa sui dati IRIS e sugli indicatori bibliometrici alla data indicata e non tiene conto di eventuali periodi di congedo obbligatorio, che in sede di domanda ASN danno diritto a incrementi percentuali dei valori. La simulazione può differire dall'esito di un’eventuale domanda ASN sia per errori di catalogazione e/o dati mancanti in IRIS, sia per la variabilità dei dati bibliometrici nel tempo. Si consideri che Anvur calcola i valori degli indicatori all'ultima data utile per la presentazione delle domande. La presente simulazione è stata realizzata sulla base delle specifiche raccolte sul tavolo ER del Focus Group IRIS coordinato dall’Università di Modena e Reggio Emilia e delle regole riportate nel DM 589/2018 e allegata Tabella A. Cineca, l’Università di Modena e Reggio Emilia e il Focus Group IRIS non si assumono alcuna responsabilità in merito all’uso che il diretto interessato o terzi faranno della simulazione. Si specifica inoltre che la simulazione contiene calcoli effettuati con dati e algoritmi di pubblico dominio e deve quindi essere considerata come un mero ausilio al calcolo svolgibile manualmente o con strumenti equivalenti.