This paper proposes the Effective Index, a formal tool to support decision processes in drug discovery. The Effective Index is based on concurrency theory and process calculi to describe incrementally complex biological systems and on Markov process theory to handle quantitative information. A running case study concerning the pathways and the drugs related to hypertension exploits the approach.
Effective Index: A Formal Measure of Drug Effects / Dematte', Lorenzo; Prandi, Davide; Priami, Corrado; Romanel, Alessandro. - ELETTRONICO. - (2007), pp. 1-8.
Effective Index: A Formal Measure of Drug Effects
Dematte', Lorenzo;Prandi, Davide;Priami, Corrado;Romanel, Alessandro
2007-01-01
Abstract
This paper proposes the Effective Index, a formal tool to support decision processes in drug discovery. The Effective Index is based on concurrency theory and process calculi to describe incrementally complex biological systems and on Markov process theory to handle quantitative information. A running case study concerning the pathways and the drugs related to hypertension exploits the approach.File in questo prodotto:
| File | Dimensione | Formato | |
|---|---|---|---|
|
TR-05-2007.pdf
accesso aperto
Tipologia:
Versione editoriale (Publisher’s layout)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
300.05 kB
Formato
Adobe PDF
|
300.05 kB | Adobe PDF | Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione
