The rapid digitalization of the healthcare domain in recent years highlighted the need for advanced predictive methods particularly based upon deep learning methods. Deep learning methods which are capable of dealing with time- series data have recently emerged in various fields such as natural language processing, machine translation, and the Intensive Care Unit (ICU). The recent applications of deep learning in ICU have increasingly received attention, and it has shown promising results for different clinical tasks; however, there is still a need for the benchmark models as far as a handful of public datasets are available in ICU. In this thesis, a novel benchmark model of four clinical tasks on a multi-center publicly available dataset is presented; we employed deep learning models to predict clinical studies. We believe this benchmark model can facilitate and accelerate the research in ICU by allowing other researchers to build on top of it. Moreover, we investigated the effectiveness of the proposed method to predict the risk of delirium in the varying observation and prediction windows, the variable ranking is provided to ease the implementation of a screening tool for helping caregivers at the bedside. Ultimately, an attention-based interpretable neural network is proposed to predict the outcome and rank the most influential variables in the model predictions’ outcome. Our experimental findings show the effectiveness of the proposed approaches in improving the application of deep learning models in daily ICU practice.

Machine learning applications in Intensive Care Unit / Sheikhalishahi, Seyedmostafa. - (2022 Apr 28), pp. 1-158. [10.15168/11572_339274]

Machine learning applications in Intensive Care Unit

Sheikhalishahi, Seyedmostafa
2022-04-28

Abstract

The rapid digitalization of the healthcare domain in recent years highlighted the need for advanced predictive methods particularly based upon deep learning methods. Deep learning methods which are capable of dealing with time- series data have recently emerged in various fields such as natural language processing, machine translation, and the Intensive Care Unit (ICU). The recent applications of deep learning in ICU have increasingly received attention, and it has shown promising results for different clinical tasks; however, there is still a need for the benchmark models as far as a handful of public datasets are available in ICU. In this thesis, a novel benchmark model of four clinical tasks on a multi-center publicly available dataset is presented; we employed deep learning models to predict clinical studies. We believe this benchmark model can facilitate and accelerate the research in ICU by allowing other researchers to build on top of it. Moreover, we investigated the effectiveness of the proposed method to predict the risk of delirium in the varying observation and prediction windows, the variable ranking is provided to ease the implementation of a screening tool for helping caregivers at the bedside. Ultimately, an attention-based interpretable neural network is proposed to predict the outcome and rank the most influential variables in the model predictions’ outcome. Our experimental findings show the effectiveness of the proposed approaches in improving the application of deep learning models in daily ICU practice.
XXXIII
2019-2020
Informatica e Telecomunicazioni (cess.31/12/07)
Information and Communication Technology
Osmani, Venet
no
eng
File in questo prodotto:
File Dimensione Formato  
phd_unitn_seyedmostafa_sheikhalishahi.pdf

embargo fino al 01/01/2023

Tipologia: Tesi di dottorato (Doctoral Thesis)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 8.68 MB
Formato Adobe PDF
8.68 MB Adobe PDF   Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11572/339274
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact