Nowadays, whenever is possible and as an alternative to open spine surgery, minimally invasive procedures are preferred to treat spinal cord injuries (SCI), with percutaneous injections or small incisions, that are faster, less traumatic, and require less recovery time. Injectable repair systems are based on materials that can be injected in the lesion site, can eventually be loaded with drugs or even cells, and act as scaffolds for the lesion repair. The review analyzes papers written from 2010 onward on injectable materials/systems used/proposed for the regenerative and combinatorial therapies of SCI and discusses the in vivo models that have been used to validate them.

Injectable scaffold-systems for the regeneration of spinal cord: Advances of the past decade / Santi, S.; Corridori, I.; Pugno, N. M.; Motta, A.; Migliaresi, C.. - In: ACS BIOMATERIALS SCIENCE & ENGINEERING. - ISSN 2373-9878. - ELETTRONICO. - 7 (2021):3(2021), pp. 983-999. [10.1021/acsbiomaterials.0c01779]

Injectable scaffold-systems for the regeneration of spinal cord: Advances of the past decade

Santi S.;Corridori I.;Pugno N. M.;Motta A.;Migliaresi C.
2021

Abstract

Nowadays, whenever is possible and as an alternative to open spine surgery, minimally invasive procedures are preferred to treat spinal cord injuries (SCI), with percutaneous injections or small incisions, that are faster, less traumatic, and require less recovery time. Injectable repair systems are based on materials that can be injected in the lesion site, can eventually be loaded with drugs or even cells, and act as scaffolds for the lesion repair. The review analyzes papers written from 2010 onward on injectable materials/systems used/proposed for the regenerative and combinatorial therapies of SCI and discusses the in vivo models that have been used to validate them.
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Santi, S.; Corridori, I.; Pugno, N. M.; Motta, A.; Migliaresi, C.
Injectable scaffold-systems for the regeneration of spinal cord: Advances of the past decade / Santi, S.; Corridori, I.; Pugno, N. M.; Motta, A.; Migliaresi, C.. - In: ACS BIOMATERIALS SCIENCE & ENGINEERING. - ISSN 2373-9878. - ELETTRONICO. - 7 (2021):3(2021), pp. 983-999. [10.1021/acsbiomaterials.0c01779]
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11572/295079
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