Silks, in particular silkworm silks, have been studied for decades as possible candidate materials for biomedical applications. Recently, great attentions have been paid to spider silks, mainly due to their unique and remarkable mechanical properties. Both materials express singular interactions with cells through specific biorecognition moieties on the core proteins making up the two silks. In this work, the silk from a Colombia spider, Linothele megatheloides (LM), which produces a single type of silk in a relatively large amount, was studied in comparison with silk from Bombyx mori silkworm, before and after degumming, with the evaluation of their chemical, mechanical and biological properties. Unexpected biological features in cell culture tests were found for the LM silk already at very early stage, so suggesting further investigation to explore its use for tailored biomedical applications.

Spider (Linothele megatheloides) and silkworm (Bombyx mori) silks: Comparative physical and biological evaluation / Yang, Yuejiao; Greco, Gabriele; Maniglio, Devid; Mazzolai, Barbara; Migliaresi, Claudio; Pugno, Nicola; Motta, Antonella. - In: MATERIALS SCIENCE AND ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS. - ISSN 0928-4931. - 2019:(2020), p. 110197. [10.1016/j.msec.2019.110197]

Spider (Linothele megatheloides) and silkworm (Bombyx mori) silks: Comparative physical and biological evaluation

Yang, Yuejiao;Greco, Gabriele;Maniglio, Devid;Migliaresi, Claudio;Pugno, Nicola;Motta, Antonella
2020-01-01

Abstract

Silks, in particular silkworm silks, have been studied for decades as possible candidate materials for biomedical applications. Recently, great attentions have been paid to spider silks, mainly due to their unique and remarkable mechanical properties. Both materials express singular interactions with cells through specific biorecognition moieties on the core proteins making up the two silks. In this work, the silk from a Colombia spider, Linothele megatheloides (LM), which produces a single type of silk in a relatively large amount, was studied in comparison with silk from Bombyx mori silkworm, before and after degumming, with the evaluation of their chemical, mechanical and biological properties. Unexpected biological features in cell culture tests were found for the LM silk already at very early stage, so suggesting further investigation to explore its use for tailored biomedical applications.
2020
Yang, Yuejiao; Greco, Gabriele; Maniglio, Devid; Mazzolai, Barbara; Migliaresi, Claudio; Pugno, Nicola; Motta, Antonella
Spider (Linothele megatheloides) and silkworm (Bombyx mori) silks: Comparative physical and biological evaluation / Yang, Yuejiao; Greco, Gabriele; Maniglio, Devid; Mazzolai, Barbara; Migliaresi, Claudio; Pugno, Nicola; Motta, Antonella. - In: MATERIALS SCIENCE AND ENGINEERING. C, BIOMIMETIC MATERIALS, SENSORS AND SYSTEMS. - ISSN 0928-4931. - 2019:(2020), p. 110197. [10.1016/j.msec.2019.110197]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/243688
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