The increasing popularity of “Mirto” liqueur, produced from Myrtus communis berries, has led to the planting of domesticated cultivars, expanding myrtle berry production. To promote the use of cultivated berries, the content in the nutraceutical compounds ellagitannins has been investigated both in spontaneous and cultivated fruits. Oenothein B and eugeniflorin D2, characterized by 1H and 13C NMR, were isolated and quantified using ultrahigh-performance liquid chromatography−diode array detector−tandem mass spectrometry (UPLC−DAD−MS/MS). The antifungal and anti-inflammatory activities of oenothein B were assayed in vitro. Large amounts of oenothein B and eugeniflorin D2 were detected in seeds (12 ± 2.4 and 5.8 ± 1.2 mg/g). The oenothein B concentration in liqueurs was 194 ± 22 mg/L. This macrocyclic ellagitannin dimer showed anti-Candida (minimal inhibitory concentration <8−64 μg/mL) and anti-inflammatory properties. Cultivated myrtle berries are a source of nutraceutical compounds. The high concentration of oenothein B in liqueur suggests a possible contribution to the organoleptic and biological properties of the beverage.

Myrtle Seeds (Myrtus communis L.) as a Rich Source of the Bioactive Ellagitannins Oenothein B and Eugeniflorin D2 / Franco, Andrea M.; Tocci, Noemi; Guella, Graziano; Dell’Agli, Mario; Sangiovanni, Enrico; Perenzoni, Daniele; Vrhovsek, Urska; Mattivi, Fulvio; Manca, Gavina. - In: ACS OMEGA. - ISSN 2470-1343. - ELETTRONICO. - 4 (2019):(2019), pp. 15966-15974. [10.1021/acsomega.9b02010]

Myrtle Seeds (Myrtus communis L.) as a Rich Source of the Bioactive Ellagitannins Oenothein B and Eugeniflorin D2

Guella, Graziano;Vrhovsek, Urska;Mattivi, Fulvio;
2019-01-01

Abstract

The increasing popularity of “Mirto” liqueur, produced from Myrtus communis berries, has led to the planting of domesticated cultivars, expanding myrtle berry production. To promote the use of cultivated berries, the content in the nutraceutical compounds ellagitannins has been investigated both in spontaneous and cultivated fruits. Oenothein B and eugeniflorin D2, characterized by 1H and 13C NMR, were isolated and quantified using ultrahigh-performance liquid chromatography−diode array detector−tandem mass spectrometry (UPLC−DAD−MS/MS). The antifungal and anti-inflammatory activities of oenothein B were assayed in vitro. Large amounts of oenothein B and eugeniflorin D2 were detected in seeds (12 ± 2.4 and 5.8 ± 1.2 mg/g). The oenothein B concentration in liqueurs was 194 ± 22 mg/L. This macrocyclic ellagitannin dimer showed anti-Candida (minimal inhibitory concentration <8−64 μg/mL) and anti-inflammatory properties. Cultivated myrtle berries are a source of nutraceutical compounds. The high concentration of oenothein B in liqueur suggests a possible contribution to the organoleptic and biological properties of the beverage.
2019
Franco, Andrea M.; Tocci, Noemi; Guella, Graziano; Dell’Agli, Mario; Sangiovanni, Enrico; Perenzoni, Daniele; Vrhovsek, Urska; Mattivi, Fulvio; Manca, Gavina
Myrtle Seeds (Myrtus communis L.) as a Rich Source of the Bioactive Ellagitannins Oenothein B and Eugeniflorin D2 / Franco, Andrea M.; Tocci, Noemi; Guella, Graziano; Dell’Agli, Mario; Sangiovanni, Enrico; Perenzoni, Daniele; Vrhovsek, Urska; Mattivi, Fulvio; Manca, Gavina. - In: ACS OMEGA. - ISSN 2470-1343. - ELETTRONICO. - 4 (2019):(2019), pp. 15966-15974. [10.1021/acsomega.9b02010]
File in questo prodotto:
File Dimensione Formato  
Franco_et_al_ACS_Omega_2019.pdf

accesso aperto

Descrizione: articolo principale
Tipologia: Versione editoriale (Publisher’s layout)
Licenza: Creative commons
Dimensione 2.59 MB
Formato Adobe PDF
2.59 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/242374
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 16
  • ???jsp.display-item.citation.isi??? 16
social impact