Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occur
Motor cortex changes in spinal cord injury: a TMS study / E., Saturno; C., Bonato; Miniussi, Carlo; V., Di Lazzaro; L., Callea. - In: NEUROLOGICAL RESEARCH. - ISSN 0161-6412. - 2008:10(2008), pp. 1084-1085. [10.1179/174313208X332968]
Motor cortex changes in spinal cord injury: a TMS study
Miniussi, Carlo;
2008-01-01
Abstract
Using paired pulse transcranial magnetic stimulation (TMS) paradigms, we studied cortical excitability in a patient with spinal cord lesion. During posterior tibial nerve stimulation, the contextual flexion of hand fingers contralateral to the stimulated lower limb had suggested a change in motor cortex excitability. Results showed a decrease in the activity of motor cortex inhibitory circuits. This could suggest that in spinal cord injury, just as in stroke and peripheral deafferentation, a disinhibition of latent synapses within the motor cortex and the rewriting of a new motor map can occurFile | Dimensione | Formato | |
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