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EnglishPhotodamage, induced by femtosecond laser radiation, was studied in thick samples of human skin tissue (healthy skin and neoplastic lesions). Photobleaching, photoionization, and thermomechanical damage effects were characterized comparatively. The laser power dependence of the damage rates allowed to connect macroscopic effects to underlying molecular processes. Optical effects were correlated to histopathological changes. Tissue alterations were found only from thermomechanical cavitation and limited to superficial layers of the epidermis. From the depth-dependencies of all damage thresholds a depth-dependent power-compensation scheme was defined allowing for damage-free deep tissue optical biopsy.
Photodamage in deep tissue two-photon optical biopsy of human skin / Dalbosco, Luca; Zanini, Giulia; D'Amato, Elvira; Tessarolo, Francesco; S., Boi; P., Bauer; Haase, Albrecht; Antolini, Renzo. - In: JOURNAL OF BIOPHOTONICS. - ISSN 1864-063X. - ELETTRONICO. - 2015,8:10(2014), pp. 816-825.
| Titolo: | Photodamage in deep tissue two-photon optical biopsy of human skin |
| Autori: | Dalbosco, Luca; Zanini, Giulia; D'Amato, Elvira; Tessarolo, Francesco; S., Boi; P., Bauer; Haase, Albrecht; Antolini, Renzo |
| Autori Unitn: | |
| Titolo del periodico: | JOURNAL OF BIOPHOTONICS |
| Anno di pubblicazione: | 2014 |
| Numero e parte del fascicolo: | 10 |
| Codice identificativo Scopus: | 2-s2.0-84944551589 |
| Codice identificativo Pubmed: | 25524048 |
| Codice identificativo ISI: | WOS:000363480400005 |
| Digital Object Identifier (DOI): | http://dx.doi.org/10.1002/jbio.201400083 |
| Handle: | http://hdl.handle.net/11572/100285 |
| Citazione: | Photodamage in deep tissue two-photon optical biopsy of human skin / Dalbosco, Luca; Zanini, Giulia; D'Amato, Elvira; Tessarolo, Francesco; S., Boi; P., Bauer; Haase, Albrecht; Antolini, Renzo. - In: JOURNAL OF BIOPHOTONICS. - ISSN 1864-063X. - ELETTRONICO. - 2015,8:10(2014), pp. 816-825. |
| Appare nelle tipologie: | 03.1 Articolo su rivista (Journal article) |
File in questo prodotto:
| File | Descrizione | Tipologia | Licenza | |
|---|---|---|---|---|
| DalboscoJBP2014preprint.pdf | Pre-print non referato (Non-refereed preprint) |  | Open Access Visualizza/Apri |
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