Umbach, Alessandro
Umbach, Alessandro
CIBIO (29/10/12-)
An optimized SpCas9 high-fidelity variant for direct protein delivery
2023-01-01 Pedrazzoli, Eleonora; Bianchi, Andrea; Umbach, Alessandro; Amistadi, Simone; Brusson, Mégane; Frati, Giacomo; Ciciani, Matteo; Badowska, Kalina Aleksandra; Arosio, Daniele; Miccio, Annarita; Cereseto, Anna; Casini, Antonio
Choice of alternative polyadenylation sites, mediated by the rna-binding protein Elavl3, plays a role in differentiation of inhibitory neuronal progenitors
2019-01-01 Grassi, E.; Santoro, R.; Umbach, Alessandro; Grosso, A.; Oliviero, S.; Neri, F.; Conti, L.; Ala, U.; Provero, P.; Dicunto, F.; Merlo, Giorgio Roberto
CRISPR-Cas strategies for the correction of Cornelia de Lange Syndrome and Cystic Fibrosis mutations
2023-01-23 Umbach, Alessandro
Functional rescue of F508del-CFTR through revertant mutations introduced by CRISPR base editing
2025-01-01 Carrozzo, Irene; Maule, Giulia; Gentile, Carmelo; Umbach, Alessandro; Ciciani, Matteo; Guidone, Daniela; De Santis, Martina; Petris, Gianluca; Vicente Galietta, Luis Juan; Arosio, Daniele; Cereseto, Anna
Generation of corrected hiPSC clones from a Cornelia de Lange Syndrome (CdLS) patient through CRISPR-Cas-based technology
2022-01-01 Umbach, Alessandro; Maule, Giulia; Kheir, Eyemen; Cutarelli, Alessandro; Foglia, Marika; Guarrera, Luca; Fava, Luca; Conti, Luciano; Garattini, Enrico; Terao, Mineko; Cereseto, Anna
The NIPBL-gene mutation of a Cornelia de Lange Syndrome patient causes deficits in the hepatocyte differentiation of induced Pluripotent Stem Cells via altered chromatin-accessibility
2024-01-01 Foglia, Marika; Guarrera, Luca; Kurosaki, Mami; Cassanmagnago, Giada Andrea; Bolis, Marco; Miduri, Matteo; Cereseto, Anna; Umbach, Alessandro; Craparotta, Ilaria; Fratelli, Maddalena; Vallerga, Arianna; Paroni, Gabriela; Zanetti, Adriana; Cavallaro, Andrea Vincenzo; Russo, Luca; Garattini, Enrico; Terao, Mineko