Memory relies on the firing of simultaneously activated neurons (engram), whose synapses are strengthened by long-term potentiation mechanisms. Optogenetic tools and a fluorescence probe to map synaptic engrams, were combined with a digital light processor device (DLP), to create in-vitro engrams and study populations of potentiated spines.
A Platform for Single Cell Optogenetics to Study Synaptic Engrams in Vitro / Zaccaria, Clara; Malkoç, Asiye; Vignoli, Beatrice; Canossa, Marco; Pavesi, Lorenzo. - (2023). (Intervento presentato al convegno Bio-Optics: Design and Application 2023 tenutosi a Vancouver, British Columbia, Canada nel 24th-27th April 2023) [10.1364/boda.2023.dtu2a.5].
A Platform for Single Cell Optogenetics to Study Synaptic Engrams in Vitro
Zaccaria, Clara;Malkoç, Asiye;Vignoli, Beatrice;Canossa, Marco;Pavesi, Lorenzo
2023-01-01
Abstract
Memory relies on the firing of simultaneously activated neurons (engram), whose synapses are strengthened by long-term potentiation mechanisms. Optogenetic tools and a fluorescence probe to map synaptic engrams, were combined with a digital light processor device (DLP), to create in-vitro engrams and study populations of potentiated spines.| File | Dimensione | Formato | |
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