Membrane systems were introduced as models of computation inspired by the structure and functioning of biological cells. Recently, membrane systems have also been shown to be suitable to model cellular processes. We introduce a new model called Membrane Systems with Peripheral and Integral Proteins. The model has compartments enclosed by membranes, floating objects, objects associated to the internal and external surfaces of the membranes and also objects integral to the membranes. The floating objects can be processed within the compartments and can interact with the objects associated to the membranes. The model can be used to represent cellular processes that involve compartments, surface and integral membrane proteins, transport and processing of chemical substances. As examples we model a circadian clock and the G-protein cycle in yeast saccharomyces cerevisiae and present a quantitative analysis using an implemented simulator. This is a preliminary version of a paper that was published in Proceedings of the International Conference on Computational Methods in Systems Biology, CMSB06, Lecture Notes in Bioinformatics, 4210:108-126, 2006. The original publication is available at www.springerlink.com

Modelling Cellular Processes using Membrane Systems with Peripheral and Integral Proteins / Cavaliere, Matteo; Sedwards, Sean. - ELETTRONICO. - (2006), pp. 1-19.

Modelling Cellular Processes using Membrane Systems with Peripheral and Integral Proteins

Sedwards, Sean
2006-01-01

Abstract

Membrane systems were introduced as models of computation inspired by the structure and functioning of biological cells. Recently, membrane systems have also been shown to be suitable to model cellular processes. We introduce a new model called Membrane Systems with Peripheral and Integral Proteins. The model has compartments enclosed by membranes, floating objects, objects associated to the internal and external surfaces of the membranes and also objects integral to the membranes. The floating objects can be processed within the compartments and can interact with the objects associated to the membranes. The model can be used to represent cellular processes that involve compartments, surface and integral membrane proteins, transport and processing of chemical substances. As examples we model a circadian clock and the G-protein cycle in yeast saccharomyces cerevisiae and present a quantitative analysis using an implemented simulator. This is a preliminary version of a paper that was published in Proceedings of the International Conference on Computational Methods in Systems Biology, CMSB06, Lecture Notes in Bioinformatics, 4210:108-126, 2006. The original publication is available at www.springerlink.com
2006
Trento
University of Trento - Centre for Computational and Systems Biology
Modelling Cellular Processes using Membrane Systems with Peripheral and Integral Proteins / Cavaliere, Matteo; Sedwards, Sean. - ELETTRONICO. - (2006), pp. 1-19.
Cavaliere, Matteo; Sedwards, Sean
File in questo prodotto:
File Dimensione Formato  
TR-07-2006.pdf

accesso aperto

Tipologia: Versione editoriale (Publisher’s layout)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 975.31 kB
Formato Adobe PDF
975.31 kB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/358709
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
  • OpenAlex ND
social impact