P-waves are vastly used to assess the outcome of catheter ablation (CA) of atrial fibrillation (AF). It remains unknown, however, if coronary sinus (CS), the key reference structure in CA procedures, follows similar patterns. This study's objective is to detect any correlations between the behavior of P-waves and CS local activation waves (LAWs) with regard to CA procedure. Duration, amplitude, area and slope rate were studied in P-waves and LAWs of five-minute recordings from 29 patients undergoing paroxysmal AF CA. Normalization (N) due to heart rate (HR) fluctuations was performed. Pearson's correlation (PC) between CA-induced variations (Delta) of P-waves and LAWs was calculated. Linear correlations between each P-wave/LAW were studied with PC and linear regression with 10-fold cross-validation. Cross-quadratic sample entropy (CQSE) assessed nonlinear correlations. PC(Delta: rho < 52.27%,p=0.015, P-wave/LAW· rho < 40.37%, p=0.001) and linear regression analysis (R{2}- adj < 16.02%, p=0.015) showed low/mediocre linear correlations. CQSE ( 0.8 - 1.3) also suggested weak nonlinear relationships. P-waves and LAWs are poorly correlated and do not describe to the same degree the substrate modification after CA. It is possible that P-waves reflect the cumulative CA-induced modifications of various atrial sites, with CS being one of them but not the dominant.

Linear and Nonlinear Correlations between Surface and Invasive Atrial Activation Features in Catheter Ablation of Paroxysmal Atrial Fibrillation / Vraka, A.; Bertomeu-Gonzalez, V.; Hornero, F.; Ravelli, F.; Alcaraz, R.; Rieta, J. J.. - In: COMPUTING IN CARDIOLOGY. - ISSN 2325-8861. - 2021:(2021), pp. 1-4. (Intervento presentato al convegno 2021 Computing in Cardiology, CinC 2021 tenutosi a Brno, Czech Republic nel 13-15 September, 2021) [10.23919/CinC53138.2021.9662868].

Linear and Nonlinear Correlations between Surface and Invasive Atrial Activation Features in Catheter Ablation of Paroxysmal Atrial Fibrillation

Ravelli, F.;
2021-01-01

Abstract

P-waves are vastly used to assess the outcome of catheter ablation (CA) of atrial fibrillation (AF). It remains unknown, however, if coronary sinus (CS), the key reference structure in CA procedures, follows similar patterns. This study's objective is to detect any correlations between the behavior of P-waves and CS local activation waves (LAWs) with regard to CA procedure. Duration, amplitude, area and slope rate were studied in P-waves and LAWs of five-minute recordings from 29 patients undergoing paroxysmal AF CA. Normalization (N) due to heart rate (HR) fluctuations was performed. Pearson's correlation (PC) between CA-induced variations (Delta) of P-waves and LAWs was calculated. Linear correlations between each P-wave/LAW were studied with PC and linear regression with 10-fold cross-validation. Cross-quadratic sample entropy (CQSE) assessed nonlinear correlations. PC(Delta: rho < 52.27%,p=0.015, P-wave/LAW· rho < 40.37%, p=0.001) and linear regression analysis (R{2}- adj < 16.02%, p=0.015) showed low/mediocre linear correlations. CQSE ( 0.8 - 1.3) also suggested weak nonlinear relationships. P-waves and LAWs are poorly correlated and do not describe to the same degree the substrate modification after CA. It is possible that P-waves reflect the cumulative CA-induced modifications of various atrial sites, with CS being one of them but not the dominant.
2021
2021 Computing in Cardiology (CinC)
Piscataway, NJ USA
IEEE Computer Society
978-1-6654-7916-5
Vraka, A.; Bertomeu-Gonzalez, V.; Hornero, F.; Ravelli, F.; Alcaraz, R.; Rieta, J. J.
Linear and Nonlinear Correlations between Surface and Invasive Atrial Activation Features in Catheter Ablation of Paroxysmal Atrial Fibrillation / Vraka, A.; Bertomeu-Gonzalez, V.; Hornero, F.; Ravelli, F.; Alcaraz, R.; Rieta, J. J.. - In: COMPUTING IN CARDIOLOGY. - ISSN 2325-8861. - 2021:(2021), pp. 1-4. (Intervento presentato al convegno 2021 Computing in Cardiology, CinC 2021 tenutosi a Brno, Czech Republic nel 13-15 September, 2021) [10.23919/CinC53138.2021.9662868].
File in questo prodotto:
File Dimensione Formato  
Linear_and_Nonlinear_Correlations_Vraka et al CinC 2021.pdf

Solo gestori archivio

Tipologia: Versione editoriale (Publisher’s layout)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 662.08 kB
Formato Adobe PDF
662.08 kB Adobe PDF   Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/344642
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact