The inhibition by anthocyanins of the free radical-mediated peroxidation of linoleic acid in a SDS micelle system was studied at pH 7.4 and at 378C, by oxygraphic and ESR tecniques. The number of peroxyl radicals trapped by anthocyanins and the efficiency of these molecules in the trapping reaction, which are two fundamental aspects of the antioxidant action, were measured and discussed in the light of the molecular structure. In particular the contribution of the substituents to the efficiency is ZOH . ZOCH3 . ZH. By ESR we found that the free radicals of anthocyanins are generated in the inhibition of the peroxidation of linoleic acid. The life time of these radical intermediates, the concentration of which ranges from 7 to 59 nM under our experimental conditions, is strictly correlated with the anthocyanin efficiency and with the heat of formation of the radical, as calculated by a semiempirical molecular orbital approach.

Peroxyl radical trapping activity of anthocyanins and generation of free radical intermediates / M., Rossetto; P., Vanzani; M., Lunelli; Scarpa, Marina; Mattivi, Fulvio; A., Rigo. - In: FREE RADICAL RESEARCH. - ISSN 1071-5762. - STAMPA. - Vol. 41:no. 7(2007), pp. 854-859. [10.1080/10715760701261533]

Peroxyl radical trapping activity of anthocyanins and generation of free radical intermediates

Scarpa, Marina;Mattivi, Fulvio;
2007-01-01

Abstract

The inhibition by anthocyanins of the free radical-mediated peroxidation of linoleic acid in a SDS micelle system was studied at pH 7.4 and at 378C, by oxygraphic and ESR tecniques. The number of peroxyl radicals trapped by anthocyanins and the efficiency of these molecules in the trapping reaction, which are two fundamental aspects of the antioxidant action, were measured and discussed in the light of the molecular structure. In particular the contribution of the substituents to the efficiency is ZOH . ZOCH3 . ZH. By ESR we found that the free radicals of anthocyanins are generated in the inhibition of the peroxidation of linoleic acid. The life time of these radical intermediates, the concentration of which ranges from 7 to 59 nM under our experimental conditions, is strictly correlated with the anthocyanin efficiency and with the heat of formation of the radical, as calculated by a semiempirical molecular orbital approach.
2007
no. 7
M., Rossetto; P., Vanzani; M., Lunelli; Scarpa, Marina; Mattivi, Fulvio; A., Rigo
Peroxyl radical trapping activity of anthocyanins and generation of free radical intermediates / M., Rossetto; P., Vanzani; M., Lunelli; Scarpa, Marina; Mattivi, Fulvio; A., Rigo. - In: FREE RADICAL RESEARCH. - ISSN 1071-5762. - STAMPA. - Vol. 41:no. 7(2007), pp. 854-859. [10.1080/10715760701261533]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11572/70394
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