Sfoglia per Autore Nardella, Caterina
Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein
2001-01-01 Pallaoro, M.; Lahm, A.; Biasiol, G.; Brunetti, M.; Nardella, C.; Orsatti, L.; Bonelli, F.; Orru, S.; Narjes, F.; Steinkuhler, C.
Radiolabeled heparan sulfate immobilized on microplate as substrate for the detection of heparanase activity
2004-01-01 Nardella, C.; Steinkuhler, C.
Mechanism of Activation of Human Heparanase Investigated by Protein Engineering
2004-01-01 Nardella, C.; Lahm, A.; Pallaoro, M.; Brunetti, M.; Vannini, A.; Steinkuhler, C.
Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer
2008-01-01 Carracedo, A.; Ma, L.; Teruya-Feldstein, J.; Rojo, F.; Salmena, L.; Alimonti, A.; Egia, A.; Sasaki, A. T.; Thomas, G.; Kozma, S. C.; Papa, A.; Nardella, C.; Cantley, L. C.; Baselga, J.; Pandolfi, P. P.
Aberrant Rheb-mediated mTORC1 activation and Pten haploinsufficiency are cooperative oncogenic events
2008-01-01 Nardella, C.; Chen, Z.; Salmena, L.; Carracedo, A.; Alimonti, A.; Egia, A.; Carver, B.; Gerald, W.; Cordon-Cardo, C.; Pandolfi, P. P.
Differential requirement of mTOR in postmitotic tissues and tumorigenesis
2009-01-01 Nardella, C.; Carracedo, A.; Alimonti, A.; Hobbs, R. M.; Clohessy, J. G.; Chen, Zheng; Egia, A.; Fornari, A.; Fiorentino, M.; Loda, M.; Kozma, S. C.; Thomas, G.; Cordon-Cardo, C.; Pandolfi, P. P.
ETS rearrangements and prostate cancer initiation
2009-01-01 Carver, B. S.; Tran, J.; Chen, Z.; Carracedo-Perez, A.; Alimonti, A.; Nardella, C.; Gopalan, A.; Scardino, P. T.; Cordon-Cardo, C.; Gerald, W.; Pandolfi, P. P.
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate
2009-01-01 Carver, B. S.; Tran, J.; Gopalan, A.; Chen, Z.; Shaikh, S.; Carracedo, A.; Alimonti, A.; Nardella, C.; Varmeh, S.; Scardino, P. T.; Cordon-Cardo, C.; Gerald, W.; Pandolfi, P. P.
Skp2 targeting suppresses tumorigenesis by Arf-p53-independent cellular senescence
2010-01-01 Lin, H. -K.; Chen, Z.; Wang, G.; Nardella, C.; Lee, S. -W.; Chan, C. -H.; Yang, W. -L.; Wang, J.; Egia, A.; Nakayama, K. I.; Cordon-Cardo, C.; Teruya-Feldstein, J.; Pandolfi, P. P.
A novel type of cellular senescence that can be enhanced in mouse models and human tumor xenografts to suppress prostate tumorigenesis
2010-01-01 Alimonti, A.; Nardella, C.; Chen, Z.; Clohessy, J. G.; Carracedo, A.; Trotman, L. C.; Cheng, K.; Varmeh, S.; Kozma, S. C.; Thomas, G.; Rosivatz, E.; Woscholski, R.; Cognetti, F.; Scher, H. I.; Pandolfi, P. P.
Faithfull modeling of PTEN loss driven diseases in the mouse
2010-01-01 Nardella, Caterina; Carracedo, Arkaitz; Salmena, Leonardo; Pandolfi, Pier Paolo
Subtle variations in Pten dose determine cancer susceptibility
2010-01-01 Alimonti, A.; Carracedo, A.; Clohessy, J. G.; Trotman, L. C.; Nardella, C.; Egia, A.; Salmena, L.; Sampieri, K.; Haveman, W. J.; Brogi, E.; Richardson, A. L.; Zhang, J.; Pandolfi, P. P.
Differential expression of S6K2 dictates tissue-specific requirement for S6K1 in mediating aberrant mTORC1 signaling and tumorigenesis
2011-01-01 Nardella, Caterina; Lunardi, Andrea; Fedele, Giuseppe; Clohessy, John G.; Alimonti, Andrea; Kozma, Sara C.; Thomas, George; Loda, Massimo; Pandolfi, Pier Paolo
The APL paradigm and the "co-clinical trial" project
2011-01-01 Nardella, Caterina; Lunardi, Andrea; Patnaik, Akash; Cantley, Lewis C.; Pandolfi, Pier Paolo
Pro-senescence therapy for cancer treatment
2011-01-01 Nardella, C.; Clohessy, J. G.; Alimonti, A.; Pandolfi, P. P.
Translation-dependent mechanisms lead to PML upregulation and mediate oncogenic K-RAS-induced cellular senescence
2012-01-01 Scaglioni, P. P.; Rabellino, A.; Yung, T. M.; Bernardi, R.; Choi, S.; Konstantinidou, G.; Nardella, C.; Cheng, K.; Pandolfi, P. P.
Combining a PI3K inhibitor with a PARP inhibitor provides an effective therapy for BRCA1-related breast cancer
2012-01-01 Juvekar, A.; Burga, L. N.; Hu, H.; Lunsford, E. P.; Ibrahim, Y. H.; Balmana, J.; Rajendran, A.; Papa, A.; Spencer, K.; Lyssiotis, C. A.; Nardella, C.; Pandolfi, P. P.; Baselga, J.; Scully, R.; Asara, J. M.; Cantley, L. C.; Wulf, G. M.
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
2013-01-01 Lunardi, Andrea; Ala, Ugo; Epping, Mirjam T.; Salmena, Leonardo; Clohessy, John G.; Webster, Kaitlyn A.; Wang, Guocan; Mazzucchelli, Roberta; Bianconi, Maristella; Stack, Edward C.; Lis, Rosina; Patnaik, Akash; Cantley, Lewis C.; Bubley, Glenn; Cordon Cardo, Carlos; Gerald, William L.; Montironi, Rodolfo; Signoretti, Sabina; Loda, Massimo; Nardella, Caterina; Pandolfi, Pier Paolo
Zbtb7a suppresses prostate cancer through repression of a Sox9-dependent pathway for cellular senescence bypass and tumor invasion
2013-01-01 Wang, Guocan; Lunardi, Andrea; Zhang, Jiangwen; Chen, Zhenbang; Ala, Ugo; Webster, Kaitlyn A.; Tay, Yvonne; Gonzalez Billalabeitia, Enrique; Egia, Ainara; Shaffer, David R.; Carver, Brett; Liu, Xue Song; Taulli, Riccardo; Kuo, Winston Patrick; Nardella, Caterina; Signoretti, Sabina; Cordon Cardo, Carlos; Gerald, William L.; Pandolfi, Pier Paolo
MUC1 is a potential target for the treatment of acute myeloid leukemia stem cells
2013-01-01 Stroopinsky, D.; Rosenblatt, J.; Ito, K.; Mills, H.; Yin, L.; Rajabi, H.; Vasir, B.; Kufe, T.; Luptakova, K.; Arnason, J.; Nardella, Caterina; Levine, J. D.; Joyce, R. M.; Galinsky, I.; Reiter, Y.; Stone, R. M.; Pandolfi, P. P.; Kufe, D.; Avigan, D.
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